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Protein

Serine carboxypeptidase 1

Gene

CBP1

Organism
Oryza sativa subsp. japonica (Rice)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at transcript leveli

Functioni

Catalytic activityi

Release of a C-terminal amino acid with broad specificity.PROSITE-ProRule annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei194 – 1941By similarity
Active sitei434 – 4341By similarity
Active sitei487 – 4871By similarity

GO - Molecular functioni

Complete GO annotation...

Keywords - Molecular functioni

Carboxypeptidase, Hydrolase, Protease

Protein family/group databases

ESTHERiorysa-cbp1. Carboxypeptidase_S10.

Names & Taxonomyi

Protein namesi
Recommended name:
Serine carboxypeptidase 1 (EC:3.4.16.5)
Alternative name(s):
Carboxypeptidase C
Serine carboxypeptidase I
Cleaved into the following 2 chains:
Alternative name(s):
Serine carboxypeptidase I chain A
Alternative name(s):
Serine carboxypeptidase I chain B
Gene namesi
Name:CBP1
Ordered Locus Names:Os12g0257000, LOC_Os12g15470
OrganismiOryza sativa subsp. japonica (Rice)
Taxonomic identifieri39947 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaLiliopsidaPoalesPoaceaeBOP cladeOryzoideaeOryzeaeOryzinaeOryza
ProteomesiUP000000763 Componenti: Chromosome 12

Organism-specific databases

GrameneiP37890.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Signal peptidei1 – 2525Sequence AnalysisAdd
BLAST
Propeptidei26 – 3611Sequence AnalysisPRO_0000004304Add
BLAST
Chaini37 – 510474Serine carboxypeptidase 1PRO_0000004305Add
BLAST
Chaini37 – 302266Serine carboxypeptidase 1 chain ABy similarityPRO_0000274566Add
BLAST
Propeptidei303 – 36260Linker peptideBy similarityPRO_0000274567Add
BLAST
Chaini363 – 510148Serine carboxypeptidase 1 chain BBy similarityPRO_0000274568Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Disulfide bondi98 ↔ 399Interchain (between A and B chains)By similarity
Glycosylationi154 – 1541N-linked (GlcNAc...)Sequence Analysis
Disulfide bondi262 ↔ 274By similarity
Glycosylationi268 – 2681N-linked (GlcNAc...)Sequence Analysis
Disulfide bondi297 ↔ 366Interchain (between A and B chains)By similarity
Glycosylationi418 – 4181N-linked (GlcNAc...)Sequence Analysis

Keywords - PTMi

Disulfide bond, Glycoprotein, Zymogen

Proteomic databases

PaxDbiP37890.
PRIDEiP37890.

Expressioni

Gene expression databases

ExpressionAtlasiP37890. baseline and differential.

Interactioni

Protein-protein interaction databases

STRINGi39947.LOC_Os12g15470.1.

Structurei

3D structure databases

ProteinModelPortaliP37890.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Motif

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Motifi508 – 5103Microbody targeting signalSequence Analysis

Sequence similaritiesi

Belongs to the peptidase S10 family.Curated

Keywords - Domaini

Signal

Phylogenomic databases

eggNOGiCOG2939.
InParanoidiP37890.
KOiK16296.

Family and domain databases

Gene3Di3.40.50.1820. 2 hits.
InterProiIPR029058. AB_hydrolase.
IPR001563. Peptidase_S10.
IPR018202. Peptidase_S10_AS.
[Graphical view]
PANTHERiPTHR11802. PTHR11802. 1 hit.
PfamiPF00450. Peptidase_S10. 1 hit.
[Graphical view]
PRINTSiPR00724. CRBOXYPTASEC.
SUPFAMiSSF53474. SSF53474. 2 hits.
PROSITEiPS00560. CARBOXYPEPT_SER_HIS. 1 hit.
PS00131. CARBOXYPEPT_SER_SER. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

P37890-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MARRGRRSLA SPAVAIALFV FLAYGGGGGG GGVCEAAPAS AVVKSVPGFD
60 70 80 90 100
GALPSKHYAG YVTVEEQHGR NLFYYLVESE RDPAKDPLVL WLNGGPGCSS
110 120 130 140 150
FDGFVYEHGP FNFESGGSAK SLPKLHLNPY SWSKVSSVIY LDSPAGVGLS
160 170 180 190 200
YSKNTSDYNT GDLKTAADSH TFLLKWFQLY PEFLSNPFYI AGESYAGVYV
210 220 230 240 250
PTLSHEVVKG LHDGVKPTIN FKGYMVGNGV CDTVFDGNAL VPFAHGMALI
260 270 280 290 300
SDDIYQEAQT ACHGNYWNTT TDKCENALYK VDTSINDLNI YDILEPCYHS
310 320 330 340 350
KTIKKVTPAN TKLPKSFQHL GTTTKPLAVR TRMHGRAWPL RAPVRAGRVP
360 370 380 390 400
SWQEFARGSR PSGVPCMSDE VATAWLNNDD VRAAIHAQPV SSIGSWLICT
410 420 430 440 450
NVLDFIHDAG SMISYHKNLT GQGYRAFIYS GDHDMCVPYT GTEAWTRSLG
460 470 480 490 500
YGVIDSWRPW HLNGQVSGYT QGYEHGLTFA TIKGAGHTVP EYKPQESLAF
510
YSRWLAGSKL
Length:510
Mass (Da):55,710
Last modified:October 1, 1994 - v1
Checksum:i28896247FA1371CF
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Sequence conflicti253 – 2531D → G in AK064874 (PubMed:12869764).Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
D17586 Genomic DNA. Translation: BAA04510.1.
DP000011 Genomic DNA. Translation: ABA96977.2.
AP008218 Genomic DNA. Translation: BAF29529.1.
AK064874 mRNA. No translation available.
PIRiS43516.
RefSeqiNP_001066510.1. NM_001073042.1.
UniGeneiOs.3451.

Genome annotation databases

EnsemblPlantsiOS12T0257000-01; OS12T0257000-01; OS12G0257000.
GeneIDi4351908.
KEGGiosa:4351908.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
D17586 Genomic DNA. Translation: BAA04510.1.
DP000011 Genomic DNA. Translation: ABA96977.2.
AP008218 Genomic DNA. Translation: BAF29529.1.
AK064874 mRNA. No translation available.
PIRiS43516.
RefSeqiNP_001066510.1. NM_001073042.1.
UniGeneiOs.3451.

3D structure databases

ProteinModelPortaliP37890.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi39947.LOC_Os12g15470.1.

Protein family/group databases

ESTHERiorysa-cbp1. Carboxypeptidase_S10.

Proteomic databases

PaxDbiP37890.
PRIDEiP37890.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblPlantsiOS12T0257000-01; OS12T0257000-01; OS12G0257000.
GeneIDi4351908.
KEGGiosa:4351908.

Organism-specific databases

GrameneiP37890.

Phylogenomic databases

eggNOGiCOG2939.
InParanoidiP37890.
KOiK16296.

Gene expression databases

ExpressionAtlasiP37890. baseline and differential.

Family and domain databases

Gene3Di3.40.50.1820. 2 hits.
InterProiIPR029058. AB_hydrolase.
IPR001563. Peptidase_S10.
IPR018202. Peptidase_S10_AS.
[Graphical view]
PANTHERiPTHR11802. PTHR11802. 1 hit.
PfamiPF00450. Peptidase_S10. 1 hit.
[Graphical view]
PRINTSiPR00724. CRBOXYPTASEC.
SUPFAMiSSF53474. SSF53474. 2 hits.
PROSITEiPS00560. CARBOXYPEPT_SER_HIS. 1 hit.
PS00131. CARBOXYPEPT_SER_SER. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. "Cloning and sequencing of the gene for type I carboxypeptidase in rice."
    Washio K., Ishikawa K.
    Biochim. Biophys. Acta 1199:311-314(1994) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
    Strain: cv. Yukihikari.
  2. "The sequence of rice chromosomes 11 and 12, rich in disease resistance genes and recent gene duplications."
    The rice chromosomes 11 and 12 sequencing consortia
    BMC Biol. 3:20-20(2005) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: cv. Nipponbare.
  3. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: cv. Nipponbare.
  4. "The rice annotation project database (RAP-DB): 2008 update."
    The rice annotation project (RAP)
    Nucleic Acids Res. 36:D1028-D1033(2008) [PubMed] [Europe PMC] [Abstract]
    Cited for: GENOME REANNOTATION.
    Strain: cv. Nipponbare.
  5. "Collection, mapping, and annotation of over 28,000 cDNA clones from japonica rice."
    The rice full-length cDNA consortium
    Science 301:376-379(2003) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Strain: cv. Nipponbare.

Entry informationi

Entry nameiCBP1_ORYSJ
AccessioniPrimary (citable) accession number: P37890
Secondary accession number(s): Q2QUQ3
Entry historyi
Integrated into UniProtKB/Swiss-Prot: October 1, 1994
Last sequence update: October 1, 1994
Last modified: June 24, 2015
This is version 103 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Peptidase families
    Classification of peptidase families and list of entries
  2. Oryza sativa (rice)
    Index of Oryza sativa entries and their corresponding gene designations
  3. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.