Reviewed, UniProtKB/Swiss-Prot P37841 (UCRI_SOLTU)

Names and origin

Protein names

Recommended name:
    Cytochrome b-c1 complex subunit Rieske, mitochondrial
    EC=1.10.2.2
Alternative name(s):
    Ubiquinol-cytochrome c reductase iron-sulfur subunit
    Rieske iron-sulfur protein
      Short name=RISP
    Complex III subunit 5

Gene names

Name:

FES1

Organism

Solanum tuberosum (Potato)

Taxonomic identifier

4113 [NCBI]

Taxonomic lineage

Eukaryota › Viridiplantae › Streptophyta › Embryophyta › Tracheophyta › Spermatophyta › Magnoliophyta › eudicotyledons › core eudicotyledons › asterids › lamiids › Solanales › Solanaceae › Solanoideae › Solaneae › Solanum

Protein attributes

Sequence length	265 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is further processed into a mature form.
Protein existence	Evidence at protein level.

General annotation (Comments)

Function	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis.
Catalytic activity	QH(2) + 2 ferricytochrome c = Q + 2 ferrocytochrome c + 2 H(+).
Cofactor	Binds 1 2Fe-2S cluster per subunit By similarity.
Subunit structure	The bc1 complex contains 10 subunits; 3 respiratory subunits, 2 core proteins and 5 low-molecular weight proteins.
Subcellular location	Mitochondrion inner membrane.
Miscellaneous	The Rieske protein is a high potential 2Fe-2S protein.
Sequence similarities	Contains 1 Rieske domain.

Ontologies

Keywords
Biological process	Electron transport Respiratory chain Transport
Cellular component	Membrane Mitochondrion Mitochondrion inner membrane
Domain	Transit peptide Transmembrane
Ligand	2Fe-2S Iron Iron-sulfur Metal-binding
Molecular function	Oxidoreductase
Technical term	Direct protein sequencing
Gene Ontology (GO)
Biological process	electron transport chain Inferred from electronic annotation. Source: UniProtKB-KW transport Inferred from electronic annotation. Source: UniProtKB-KW
Cellular component	integral to membrane Inferred from electronic annotation. Source: UniProtKB-KW mitochondrial respiratory chain Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	2 iron, 2 sulfur cluster binding Inferred from electronic annotation. Source: InterPro electron carrier activity Inferred from electronic annotation. Source: InterPro iron ion binding Inferred from electronic annotation. Source: UniProtKB-KW ubiquinol-cytochrome-c reductase activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Transit peptide	1 – 53	53	Mitochondrion
	Chain	54 – 265	212	Cytochrome b-c1 complex subunit Rieske, mitochondrial		PRO_0000030675
Regions
	Domain	175 – 263	89	Rieske
Sites
	Metal binding	208	1	Iron-sulfur (2Fe-2S) By similarity
	Metal binding	210	1	Iron-sulfur (2Fe-2S); via pros nitrogen By similarity
	Metal binding	227	1	Iron-sulfur (2Fe-2S) By similarity
	Metal binding	230	1	Iron-sulfur (2Fe-2S); via pros nitrogen By similarity
Amino acid modifications
	Disulfide bond	213 ↔ 229		By similarity

Sequences

	Sequence		Length	Mass (Da)
	P37841-1 [UniParc]. Last modified October 1, 1994. Version 1. Checksum: 78C8C0AC6F09D932	FASTA	265	28,841
	10 20 30 40 50 60 MLRVAGRRLS SSAARSSSTF FTRSSFTVTD DSSPARSPSP SLTSSFLDQI RGFSSNSVSP 70 80 90 100 110 120 AHQLGLVSDL PATVAAIKNP SSKIVYDDSN HERYPPGDPS KRAFAYFVLT GGRFVYASSV 130 140 150 160 170 180 RLLILKFVLS MSASKDVLAL ASLEVDLSSI EPGSTVTVKW RGKPVFIRRR TDDDIKLANS 190 200 210 220 230 240 VDLGTLRDPQ QDAERVKNPE WLVVVGVCTH LGCIPLPNAG DFGGWFCPCH GSHYDISGRI 250 260 RKGPAPYNLE VPTYSFLEEN KLLIG

References

[1]

"Molecular features, processing and import of the Rieske iron-sulfur protein from potato mitochondria." Emmermann M., Clericus M., Braun H.P., Mozo T., Heins L., Kruft V., Schmitz U.K. Plant Mol. Biol. 25:271-281(1994) [PubMed: 8018875] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [MRNA], PARTIAL PROTEIN SEQUENCE. Strain: cv. Desiree. Tissue: Leaf.

Cross-references

Sequence databases
EMBLGenBankDDBJ	X79332 mRNA. Translation: CAA55894.1.
PIR	S46534.
3D structure databases
HSSP	HSSP built from PDB template 1RIE based on UniProtKB P13272.
ModBase	Search...
Family and domain databases
InterPro	IPR014349. Rieske. IPR005805. Rieske_C. IPR006317. Rieske_proteo. IPR005806. Rieske_reg. IPR004192. UCR_TM_region. [Graphical view]
Gene3D	G3DSA:2.102.10.10. Rieske_reg. 1 hit.
PANTHER	PTHR10134. Rieske. 1 hit.
Pfam	PF00355. Rieske. 1 hit. PF02921. UCR_TM. 1 hit. [Graphical view]
PRINTS	PR00162. RIESKE.
TIGRFAMs	TIGR01416. Rieske_proteo. 1 hit.
PROSITE	PS51296. RIESKE. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

UCRI_SOLTU

Accession

Primary (citable) accession number: P37841

Entry history

Integrated into UniProtKB/Swiss-Prot:	October 1, 1994
Last sequence update:	October 1, 1994
Last modified:	November 25, 2008
This is version 58 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

PPAP (Plant Proteome Annotation Project)