P37822 (AROG_SOLTU) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Phospho-2-dehydro-3-deoxyheptonate aldolase 2, chloroplastic
EC=2.5.1.54

Alternative name(s):
3-deoxy-D-arabino-heptulosonate 7-phosphate synthase 2
DAHP synthase 2
Phospho-2-keto-3-deoxyheptonate aldolase 2

Gene names

Name:	SHKB
Synonyms:	ARO2

Organism

Solanum tuberosum (Potato)

Taxonomic identifier

4113 [NCBI]

Taxonomic lineage

Eukaryota › Viridiplantae › Streptophyta › Embryophyta › Tracheophyta › Spermatophyta › Magnoliophyta › eudicotyledons › core eudicotyledons › asterids › lamiids › Solanales › Solanaceae › Solanoideae › Solaneae › Solanum

Protein attributes

Sequence length	511 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is further processed into a mature form.
Protein existence	Evidence at transcript level

General annotation (Comments)

Catalytic activity	Phosphoenolpyruvate + D-erythrose 4-phosphate + H2O = 3-deoxy-D-arabino-hept-2-ulosonate 7-phosphate + phosphate.
Pathway	Metabolic intermediate biosynthesis; chorismate biosynthesis; chorismate from D-erythrose 4-phosphate and phosphoenolpyruvate: step 1/7.
Subcellular location	Plastid › chloroplast.
Tissue specificity	Leaves, stems, tuber and roots.
Induction	By glyphosate, wounding and fungal elicitor.
Sequence similarities	Belongs to the class-II DAHP synthase family.

Ontologies

Keywords
Biological process	Amino-acid biosynthesis Aromatic amino acid biosynthesis
Cellular component	Chloroplast Plastid
Domain	Transit peptide
Molecular function	Transferase
Gene Ontology (GO)
Biological process	aromatic amino acid family biosynthetic process Inferred from electronic annotation. Source: UniProtKB-KW
Cellular component	chloroplast Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	3-deoxy-7-phosphoheptulonate synthase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Transit peptide	1 – ?		Chloroplast
	Chain	? – 511		Phospho-2-dehydro-3-deoxyheptonate aldolase 2, chloroplastic		PRO_0000002303

Sequences

	Sequence		Length	Mass (Da)
	P37822 [UniParc]. Last modified October 1, 1994. Version 1. Checksum: 71FED97113BD26B6	FASTA	511	56,924
	10 20 30 40 50 60 MALSNTLSLS SSKSLVQSHL LHNPLPQPRF SLFPTTQHGR RHPISAVHAA EPSKTAVKQG 70 80 90 100 110 120 KWSLDSWKTK KALQLPEYPD EKELESVLKT LEMNPPLVFA GEARSLEEKL GEAALGKAFL 130 140 150 160 170 180 LQGGDCAESF KEFNANNIRD TFRILLQMSV VLMFGGQVPV IKVGRMAGQF AKPRSDPLEE 190 200 210 220 230 240 INGVKLPSYK GDNINGDTFD EKSRIPDPHR LIRAYMQSAA TLNLLRAFAT GGYAAMQRVT 250 260 270 280 290 300 EWNLDFVENC EQGDRYQELA HRVDEALGFM AAAGLTVDHP IMSTTDFWTS HECLLLPYEQ 310 320 330 340 350 360 ALTREDSTSG LFYDCSAHMV WVGERTRQLD GAHVEFLRGV ANPLGIKVSQ KMDPNELIKL 370 380 390 400 410 420 IDILNPANKP GRITVIVRMG AENMRVKLSH LVRAVRGAGQ IVTWVCDPMH GNTIKAPCGL 430 440 450 460 470 480 KTRAFDSILA EVRAFFDVHE QEGSHPGGIH LEMTGQNVTE CIGGSRTVTY DDLGSRYHTH 490 500 510 CDPRLNASQS LELSFIVAER LRRRRMSTQR L

References

[1]	"Cloning and sequencing of a second cDNA encoding 3-deoxy-d-arabino-heptulosonate 7-phosphate synthase from Solanum tuberosum L." Zhao J., Herrmann K.M. Plant Physiol. 100:1075-1076(1992) [PubMed: 16653023] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [MRNA]. Strain: cv. Superior. Tissue: Tuber.

Cross-references

Sequence databases
EMBL GenBank DDBJ	M95201 mRNA. Translation: AAA33840.1.
3D structure databases
ProteinModelPortal	P37822.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Family and domain databases
InterPro	IPR002480. DAHP_synth_2. [Graphical view]
PANTHER	PTHR21337. DAHP_synth_2. 1 hit.
Pfam	PF01474. DAHP_synth_2. 1 hit. [Graphical view]
TIGRFAMs	TIGR01358. DAHP_synth_II. 1 hit.
ProtoNet	Search...

Entry information

Entry name

AROG_SOLTU

Accession

Primary (citable) accession number: P37822

Entry history

Integrated into UniProtKB/Swiss-Prot:	October 1, 1994
Last sequence update:	October 1, 1994
Last modified:	September 21, 2011
This is version 66 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Plant Protein Annotation Program