Reviewed, UniProtKB/Swiss-Prot P37820 (MPG1_SULAC)

Names and origin

Protein names

Recommended name:
    Putative mannose-1-phosphate guanyltransferase
    EC=2.7.7.13
Alternative name(s):
    ATP-mannose-1-phosphate guanylyltransferase
    GDP-mannose pyrophosphorylase
    NDP-hexose pyrophosphorylase

Gene names

Name:	mpg1
Ordered Locus Names:	Saci_0196

Organism

Sulfolobus acidocaldarius [Complete proteome] [HAMAP]

Taxonomic identifier

2285 [NCBI]

Taxonomic lineage

Archaea › Crenarchaeota › Thermoprotei › Sulfolobales › Sulfolobaceae › Sulfolobus

Protein attributes

Sequence length	359 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Catalytic activity	GTP + alpha-D-mannose 1-phosphate = diphosphate + GDP-mannose.
Sequence similarities	Belongs to the transferase hexapeptide repeat family.

Ontologies

Keywords
Ligand	GTP-binding Nucleotide-binding
Molecular function	Nucleotidyltransferase Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	biosynthetic process Inferred from electronic annotation. Source: InterPro
Molecular function	GTP binding Inferred from electronic annotation. Source: UniProtKB-KW mannose-1-phosphate guanylyltransferase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 359	359	Putative mannose-1-phosphate guanyltransferase		PRO_0000068742
Experimental info
	Sequence conflict	140	1	Missing Ref.2

Sequences

	Sequence		Length	Mass (Da)
	P37820-1 [UniParc]. Last modified August 30, 2005. Version 2. Checksum: E61047D1787C1F23	FASTA	359	39,721
	10 20 30 40 50 60 MVSAIVLAGG YATRLRPLSL TKPKALLPVL GKPLMDYTLY SLASSDVDTI YLSLRVMADK 70 80 90 100 110 120 VLDHVKQLNL QKNIVSVIEE SRLGDAGPLK FINSKYNLSD DVIVVYGDIY AEIDFNKLLE 130 140 150 160 170 180 YHQSKGCNAT LTATQVEDPS RYGVLITDGH RLIQIIEKPK TPLSNLVNAG IYVFKKELLN 190 200 210 220 230 240 KIDGLSISRD FLPKLLVSDT CVSVYPYKGL WMDIGVPRDY MRINLELLTL KYPKGFISQS 250 260 270 280 290 300 AKVSEKAELF PPFYIGDNTT VGEGSSIRNS IIGVNNRIGN GSCVEESILM NDVMLGDFSL 310 320 330 340 350 IKESVIGDEV SLGKWNRVDG AIIGDGVLIH DQVFINRDTI ILPDKEVAES VYDKGKIIL

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"The genome of Sulfolobus acidocaldarius, a model organism of the Crenarchaeota." Chen L., Bruegger K., Skovgaard M., Redder P., She Q., Torarinsson E., Greve B., Awayez M., Zibat A., Klenk H.-P., Garrett R.A. J. Bacteriol. 187:4992-4999(2005) [PubMed: 15995215] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 33909 / DSM 639 / IFO 15157 / JCM 8929 / NCIB 11770.
[2]	"Nucleotide sequence, transcription and phylogeny of the gene encoding the superoxide dismutase of Sulfolobus acidocaldarius." Klenk H.-P., Schleper C., Schwass V., Brudler R. Biochim. Biophys. Acta 1174:95-98(1993) [PubMed: 8334170] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 1-142.

Cross-references

Sequence databases
EMBLGenBankDDBJ	CP000077 Genomic DNA. Translation: AAY79615.1. X63386 Genomic DNA. Translation: CAA44994.1.
PIR	S34617.
RefSeq	YP_254908.1.
3D structure databases
HSSP	HSSP built from PDB template 1H5R based on UniProtKB P37744.
ModBase	Search...
Genome annotation databases
GeneID	3474009.
GenomeReviews	Gene locus Saci_0196 in contig CP000077_GR.
KEGG	sai:Saci_0196.
NMPDR	fig|330779.3.peg.583.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	P37820.
OMA	FVEKPRE.
Enzyme and pathway databases
BioCyc	SACI330779:SACI_0196-MON.
BRENDA	2.7.7.13. 434.
Family and domain databases
InterPro	IPR001451. Hexapep_transf. IPR018357. Hexapep_transf_CS. IPR005835. NTP_transferase. [Graphical view]
Pfam	PF00132. Hexapep. 3 hits. PF00483. NTP_transferase. 1 hit. [Graphical view]
PROSITE	PS00101. HEXAPEP_TRANSFERASES. False negative. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

MPG1_SULAC

Accession

Primary (citable) accession number: P37820
Secondary accession number(s): Q4JC64

Entry history

Integrated into UniProtKB/Swiss-Prot:	October 1, 1994
Last sequence update:	August 30, 2005
Last modified:	November 3, 2009
This is version 49 of the entry and version 2 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)