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Protein

Inner membrane ABC transporter permease protein YjfF

Gene

yjfF

Organism
Escherichia coli (strain K12)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Probably part of a binding-protein-dependent transport system. Probably responsible for the translocation of the substrate across the membrane.

GO - Molecular functioni

Keywordsi

Biological processTransport

Enzyme and pathway databases

BioCyciEcoCyc:YJFF-MONOMER
MetaCyc:YJFF-MONOMER

Protein family/group databases

TCDBi3.A.1.2.25 the atp-binding cassette (abc) superfamily

Names & Taxonomyi

Protein namesi
Recommended name:
Inner membrane ABC transporter permease protein YjfF
Gene namesi
Name:yjfF
Ordered Locus Names:b4231, JW5754
OrganismiEscherichia coli (strain K12)
Taxonomic identifieri83333 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesEnterobacteriaceaeEscherichia
Proteomesi
  • UP000000318 Componenti: Chromosome
  • UP000000625 Componenti: Chromosome

Organism-specific databases

EcoGeneiEG12439 yjfF

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Topological domaini1 – 5PeriplasmicSequence analysis5
Transmembranei6 – 26HelicalSequence analysisAdd BLAST21
Topological domaini27 – 42CytoplasmicSequence analysisAdd BLAST16
Transmembranei43 – 63HelicalSequence analysisAdd BLAST21
Topological domaini64PeriplasmicSequence analysis1
Transmembranei65 – 85HelicalSequence analysisAdd BLAST21
Topological domaini86 – 88CytoplasmicSequence analysis3
Transmembranei89 – 109HelicalSequence analysisAdd BLAST21
Topological domaini110 – 113PeriplasmicSequence analysis4
Transmembranei114 – 134HelicalSequence analysisAdd BLAST21
Topological domaini135 – 159CytoplasmicSequence analysisAdd BLAST25
Transmembranei160 – 180HelicalSequence analysisAdd BLAST21
Topological domaini181 – 222PeriplasmicSequence analysisAdd BLAST42
Transmembranei223 – 243HelicalSequence analysisAdd BLAST21
Topological domaini244 – 251CytoplasmicSequence analysis8
Transmembranei252 – 272HelicalSequence analysisAdd BLAST21
Topological domaini273 – 294PeriplasmicSequence analysisAdd BLAST22
Transmembranei295 – 315HelicalSequence analysisAdd BLAST21
Topological domaini316 – 331CytoplasmicSequence analysisAdd BLAST16

GO - Cellular componenti

Keywords - Cellular componenti

Cell inner membrane, Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000602601 – 331Inner membrane ABC transporter permease protein YjfFAdd BLAST331

Proteomic databases

PaxDbiP37772
PRIDEiP37772

Interactioni

Protein-protein interaction databases

BioGridi4259315, 24 interactors
STRINGi316385.ECDH10B_4426

Structurei

3D structure databases

ProteinModelPortaliP37772
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiENOG41062B0 Bacteria
ENOG410XR1U LUCA
HOGENOMiHOG000212232
InParanoidiP37772
KOiK02057
OMAiIGFWGIS
PhylomeDBiP37772

Family and domain databases

InterProiView protein in InterPro
IPR001851 ABC_transp_permease
PfamiView protein in Pfam
PF02653 BPD_transp_2, 1 hit

Sequencei

Sequence statusi: Complete.

P37772-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MIKRNLPLMI TIGVFVLGYL YCLTQFPGFA STRVICNILT DNAFLGIIAV
60 70 80 90 100
GMTFVILSGG IDLSVGSVIA FTGVFLAKVI GDFGLSPLLA FPLVLVMGCA
110 120 130 140 150
FGAFMGLLID ALKIPAFIIT LAGMFFLRGV SYLVSEESIP INHPIYDTLS
160 170 180 190 200
SLAWKIPGGG RLSAMGLLML AVVVIGIFLA HRTRFGNQVY AIGGNATSAN
210 220 230 240 250
LMGISTRSTT IRIYMLSTGL ATLAGIVFSI YTQAGYALAG VGVELDAIAS
260 270 280 290 300
VVIGGTLLSG GVGTVLGTLF GVAIQGLIQT YINFDGTLSS WWTKIAIGIL
310 320 330
LFIFIALQRG LTVLWENRQS SPVTRVNIAQ Q
Length:331
Mass (Da):34,978
Last modified:August 14, 2001 - v3
Checksum:iA30435AA393D6C9F
GO

Sequence cautioni

The sequence AAA97128 differs from that shown. Reason: Erroneous initiation. Translation N-terminally extended.Curated

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti257L → V in X12545 (PubMed:2843822).Curated1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U14003 Genomic DNA Translation: AAA97128.1 Different initiation.
U00096 Genomic DNA Translation: AAC77188.2
AP009048 Genomic DNA Translation: BAE78231.1
X12545 mRNA No translation available.
PIRiS56457
RefSeqiNP_418652.2, NC_000913.3
WP_000596014.1, NZ_LN832404.1

Genome annotation databases

EnsemblBacteriaiAAC77188; AAC77188; b4231
BAE78231; BAE78231; BAE78231
GeneIDi948754
KEGGiecj:JW5754
eco:b4231
PATRICifig|1411691.4.peg.2471

Similar proteinsi

Entry informationi

Entry nameiYJFF_ECOLI
AccessioniPrimary (citable) accession number: P37772
Secondary accession number(s): Q2M675
Entry historyiIntegrated into UniProtKB/Swiss-Prot: October 1, 1994
Last sequence update: August 14, 2001
Last modified: March 28, 2018
This is version 134 of the entry and version 3 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome
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Main funding by: National Institutes of Health