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Protein

Uncharacterized HTH-type transcriptional regulator YfhH

Gene

yfhH

Organism
Escherichia coli (strain K12)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
DNA bindingi37 – 56H-T-H motifPROSITE-ProRule annotationAdd BLAST20

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Biological processi

Transcription, Transcription regulation

Keywords - Ligandi

DNA-binding

Enzyme and pathway databases

BioCyciEcoCyc:EG12308-MONOMER.
ECOL316407:JW2545-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Uncharacterized HTH-type transcriptional regulator YfhH
Gene namesi
Name:yfhH
Ordered Locus Names:b2561, JW2545
OrganismiEscherichia coli (strain K12)
Taxonomic identifieri83333 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesEnterobacteriaceaeEscherichia
Proteomesi
  • UP000000318 Componenti: Chromosome
  • UP000000625 Componenti: Chromosome

Organism-specific databases

EcoGeneiEG12308. yfhH.

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000686261 – 282Uncharacterized HTH-type transcriptional regulator YfhHAdd BLAST282

Proteomic databases

PaxDbiP37767.
PRIDEiP37767.

Interactioni

Protein-protein interaction databases

BioGridi4261197. 11 interactors.
DIPiDIP-12050N.
STRINGi511145.b2561.

Structurei

3D structure databases

ProteinModelPortaliP37767.
SMRiP37767.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini1 – 77HTH rpiR-typePROSITE-ProRule annotationAdd BLAST77
Domaini125 – 265SISPROSITE-ProRule annotationAdd BLAST141

Sequence similaritiesi

Contains 1 HTH rpiR-type DNA-binding domain.PROSITE-ProRule annotation
Contains 1 SIS domain.PROSITE-ProRule annotation

Phylogenomic databases

eggNOGiENOG4106G6Q. Bacteria.
COG1737. LUCA.
HOGENOMiHOG000027157.
InParanoidiP37767.
OMAiQDLEHAP.
PhylomeDBiP37767.

Family and domain databases

Gene3Di1.10.10.10. 1 hit.
InterProiIPR009057. Homeodomain-like.
IPR000281. HTH_RpiR.
IPR001347. SIS.
IPR011991. WHTH_DNA-bd_dom.
[Graphical view]
PfamiPF01418. HTH_6. 1 hit.
PF01380. SIS. 1 hit.
[Graphical view]
SUPFAMiSSF46689. SSF46689. 1 hit.
PROSITEiPS51071. HTH_RPIR. 1 hit.
PS51464. SIS. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P37767-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MNGLLRIRQR YQGLAQSDKK LADYLLLQPD TARHLSSQQL ANEAGVSQSS
60 70 80 90 100
VVKFAQKLGY KGFPALKLAL SEALASQPES PSVPIHNQIR GDDPLRLVGE
110 120 130 140 150
KLIKENTAAM YATLNVNSEE KLHECVTMLR SARRIILTGI GASGLVAQNF
160 170 180 190 200
AWKLMKIGFN AAAVRDMHAL LATVQASSPD DLLLAISYTG VRRELNLAAD
210 220 230 240 250
EMLRVGGKVL AITGFTPNAL QQRASHCLYT IAEEQATNSA SISACHAQGM
260 270 280
LTDLLFIALI QQDLELAPER IRHSEALVKK LV
Length:282
Mass (Da):30,708
Last modified:November 1, 1995 - v2
Checksum:iFF0AE2A0BF4E3C48
GO

Sequence cautioni

The sequence AAA79823 differs from that shown. Reason: Erroneous initiation. Translation N-terminally shortened.Curated
The sequence BAA10911 differs from that shown. Reason: Erroneous initiation. Translation N-terminally shortened.Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
D64044 Genomic DNA. Translation: BAA10911.1. Different initiation.
U36841 Genomic DNA. Translation: AAA79823.1. Different initiation.
U00096 Genomic DNA. Translation: AAC75614.2.
AP009048 Genomic DNA. Translation: BAE76737.1.
X72336 Genomic DNA. No translation available.
RefSeqiNP_417056.2. NC_000913.3.
WP_001013779.1. NZ_LN832404.1.

Genome annotation databases

EnsemblBacteriaiAAC75614; AAC75614; b2561.
BAE76737; BAE76737; BAE76737.
GeneIDi947030.
KEGGiecj:JW2545.
eco:b2561.
PATRICi32120521. VBIEscCol129921_2663.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
D64044 Genomic DNA. Translation: BAA10911.1. Different initiation.
U36841 Genomic DNA. Translation: AAA79823.1. Different initiation.
U00096 Genomic DNA. Translation: AAC75614.2.
AP009048 Genomic DNA. Translation: BAE76737.1.
X72336 Genomic DNA. No translation available.
RefSeqiNP_417056.2. NC_000913.3.
WP_001013779.1. NZ_LN832404.1.

3D structure databases

ProteinModelPortaliP37767.
SMRiP37767.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi4261197. 11 interactors.
DIPiDIP-12050N.
STRINGi511145.b2561.

Proteomic databases

PaxDbiP37767.
PRIDEiP37767.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAC75614; AAC75614; b2561.
BAE76737; BAE76737; BAE76737.
GeneIDi947030.
KEGGiecj:JW2545.
eco:b2561.
PATRICi32120521. VBIEscCol129921_2663.

Organism-specific databases

EchoBASEiEB2214.
EcoGeneiEG12308. yfhH.

Phylogenomic databases

eggNOGiENOG4106G6Q. Bacteria.
COG1737. LUCA.
HOGENOMiHOG000027157.
InParanoidiP37767.
OMAiQDLEHAP.
PhylomeDBiP37767.

Enzyme and pathway databases

BioCyciEcoCyc:EG12308-MONOMER.
ECOL316407:JW2545-MONOMER.

Miscellaneous databases

PROiP37767.

Family and domain databases

Gene3Di1.10.10.10. 1 hit.
InterProiIPR009057. Homeodomain-like.
IPR000281. HTH_RpiR.
IPR001347. SIS.
IPR011991. WHTH_DNA-bd_dom.
[Graphical view]
PfamiPF01418. HTH_6. 1 hit.
PF01380. SIS. 1 hit.
[Graphical view]
SUPFAMiSSF46689. SSF46689. 1 hit.
PROSITEiPS51071. HTH_RPIR. 1 hit.
PS51464. SIS. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiYFHH_ECOLI
AccessioniPrimary (citable) accession number: P37767
Secondary accession number(s): P76588, Q2MAG9
Entry historyi
Integrated into UniProtKB/Swiss-Prot: October 1, 1994
Last sequence update: November 1, 1995
Last modified: November 2, 2016
This is version 115 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Escherichia coli
    Escherichia coli (strain K12): entries and cross-references to EcoGene
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.