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Protein

Putative glycosyltransferase WbbK

Gene

wbbK

Organism
Escherichia coli (strain K12)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein predictedi

Functioni

May be a glycosyltransferase involved in the transfer of UDP-GalF and UDP-glucose.

Pathwayi: lipopolysaccharide biosynthesis

This protein is involved in the pathway lipopolysaccharide biosynthesis, which is part of Bacterial outer membrane biogenesis.
View all proteins of this organism that are known to be involved in the pathway lipopolysaccharide biosynthesis and in Bacterial outer membrane biogenesis.

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Transferase

Keywords - Biological processi

Lipopolysaccharide biosynthesis

Enzyme and pathway databases

BioCyciEcoCyc:EG11985-MONOMER.
ECOL316407:JW2017-MONOMER.
UniPathwayiUPA00030.

Protein family/group databases

CAZyiGT4. Glycosyltransferase Family 4.

Names & Taxonomyi

Protein namesi
Recommended name:
Putative glycosyltransferase WbbK
Gene namesi
Name:wbbK
Synonyms:yefI
Ordered Locus Names:b2032, JW2017
OrganismiEscherichia coli (strain K12)
Taxonomic identifieri83333 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeEscherichia
Proteomesi
  • UP000000318 Componenti: Chromosome
  • UP000000625 Componenti: Chromosome

Organism-specific databases

EcoGeneiEG11985. wbbK.

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Cell inner membrane, Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 372372Putative glycosyltransferase WbbKPRO_0000169121Add
BLAST

Proteomic databases

PaxDbiP37751.
PRIDEiP37751.

Interactioni

Protein-protein interaction databases

BioGridi4261357. 335 interactions.
DIPiDIP-11874N.
IntActiP37751. 5 interactions.
STRINGi511145.b2032.

Structurei

3D structure databases

ProteinModelPortaliP37751.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Phylogenomic databases

eggNOGiENOG4108TMJ. Bacteria.
COG0438. LUCA.
HOGENOMiHOG000054841.
InParanoidiP37751.
OMAiDLPYAHE.
OrthoDBiEOG6CZQGW.
PhylomeDBiP37751.

Family and domain databases

InterProiIPR001296. Glyco_trans_1.
[Graphical view]
PfamiPF00534. Glycos_transf_1. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P37751-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MGKSIVVVSA VNFTTGGPFT ILKKFLAATN NKENVSFIAL VHSAKELKES
60 70 80 90 100
YPWVKFIEFP EVKGSWLKRL HFEYVVCKKL SKELNATHWI CLHDITANVV
110 120 130 140 150
TKKRYVYCHN PAPFYKGILF REILMEPSFF LFKMLYGLIY KINIKKNTAV
160 170 180 190 200
FVQQFWMKEK FIKKYSINNI IVSRPEIKLS DKSQLTDDDS QFKNNPSELT
210 220 230 240 250
IFYPAVPRVF KNYELIISAA RKLKEQSNIK FLLTISGTEN AYAKYIISLA
260 270 280 290 300
EGLDNVHFLG YLDKEKIDHC YNISDIVCFP SRLETWGLPL SEAKERGKWV
310 320 330 340 350
LASDFPFTRE TLGSYEKKAF FDSNNDDMLV KLIIDFKKGN LKKDISDANF
360 370
IYRNENVLVG FDELVNFITE EH
Length:372
Mass (Da):43,188
Last modified:October 1, 1994 - v1
Checksum:iF92A0D4E71EBAF31
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U03041 Genomic DNA. Translation: AAC31636.1.
U00096 Genomic DNA. Translation: AAC75093.1.
AP009048 Genomic DNA. Translation: BAA15874.1.
U09876 Genomic DNA. Translation: AAB88407.1.
L19537 Genomic DNA. Translation: AAB49381.1.
PIRiI69647.
RefSeqiNP_416536.1. NC_000913.3.
WP_000520320.1. NZ_LN832404.1.

Genome annotation databases

EnsemblBacteriaiAAC75093; AAC75093; b2032.
BAA15874; BAA15874; BAA15874.
GeneIDi946555.
KEGGiecj:JW2017.
eco:b2032.
PATRICi32119399. VBIEscCol129921_2109.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U03041 Genomic DNA. Translation: AAC31636.1.
U00096 Genomic DNA. Translation: AAC75093.1.
AP009048 Genomic DNA. Translation: BAA15874.1.
U09876 Genomic DNA. Translation: AAB88407.1.
L19537 Genomic DNA. Translation: AAB49381.1.
PIRiI69647.
RefSeqiNP_416536.1. NC_000913.3.
WP_000520320.1. NZ_LN832404.1.

3D structure databases

ProteinModelPortaliP37751.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi4261357. 335 interactions.
DIPiDIP-11874N.
IntActiP37751. 5 interactions.
STRINGi511145.b2032.

Protein family/group databases

CAZyiGT4. Glycosyltransferase Family 4.

Proteomic databases

PaxDbiP37751.
PRIDEiP37751.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAC75093; AAC75093; b2032.
BAA15874; BAA15874; BAA15874.
GeneIDi946555.
KEGGiecj:JW2017.
eco:b2032.
PATRICi32119399. VBIEscCol129921_2109.

Organism-specific databases

EchoBASEiEB1928.
EcoGeneiEG11985. wbbK.

Phylogenomic databases

eggNOGiENOG4108TMJ. Bacteria.
COG0438. LUCA.
HOGENOMiHOG000054841.
InParanoidiP37751.
OMAiDLPYAHE.
OrthoDBiEOG6CZQGW.
PhylomeDBiP37751.

Enzyme and pathway databases

UniPathwayiUPA00030.
BioCyciEcoCyc:EG11985-MONOMER.
ECOL316407:JW2017-MONOMER.

Miscellaneous databases

PROiP37751.

Family and domain databases

InterProiIPR001296. Glyco_trans_1.
[Graphical view]
PfamiPF00534. Glycos_transf_1. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. "Genetic analysis of the O-specific lipopolysaccharide biosynthesis region (rfb) of Escherichia coli K-12 W3110: identification of genes that confer group 6 specificity to Shigella flexneri serotypes Y and 4a."
    Yao Z., Valvano M.A.
    J. Bacteriol. 176:4133-4143(1994) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
    Strain: K12 / W3110 / ATCC 27325 / DSM 5911.
  2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: K12 / W3110 / ATCC 27325 / DSM 5911.
  3. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: K12 / MG1655 / ATCC 47076.
  4. "Highly accurate genome sequences of Escherichia coli K-12 strains MG1655 and W3110."
    Hayashi K., Morooka N., Yamamoto Y., Fujita K., Isono K., Choi S., Ohtsubo E., Baba T., Wanner B.L., Mori H., Horiuchi T.
    Mol. Syst. Biol. 2:E1-E5(2006) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: K12 / W3110 / ATCC 27325 / DSM 5911.
  5. "Structure of the O antigen of Escherichia coli K-12 and the sequence of its rfb gene cluster."
    Stevenson G., Neal B., Liu D., Hobbs M., Packer N.H., Batley M., Redmond J.W., Lindquist L., Reeves P.R.
    J. Bacteriol. 176:4144-4156(1994) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 1-319.
    Strain: K12 / WG1.
  6. "Escherichia coli K12 regains its O antigen."
    Liu D., Reeves P.R.
    Microbiology 140:49-57(1994) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 149-372.
    Strain: K12 / WG1.

Entry informationi

Entry nameiWBBK_ECOLI
AccessioniPrimary (citable) accession number: P37751
Entry historyi
Integrated into UniProtKB/Swiss-Prot: October 1, 1994
Last sequence update: October 1, 1994
Last modified: January 20, 2016
This is version 108 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Escherichia coli
    Escherichia coli (strain K12): entries and cross-references to EcoGene
  2. PATHWAY comments
    Index of metabolic and biosynthesis pathways

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.