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Protein

Beta-1,6-galactofuranosyltransferase WbbI

Gene

wbbI

Organism
Escherichia coli (strain K12)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at protein leveli

Functioni

Involved in the transfer of galactofuranose (Galf) onto an alpha-D-gluco-configured acceptor substrate to form a beta-1,6-linkage. It uses n-octyl alpha-D-glucopyranoside as an acceptor substrate for the addition of galactofuranose from the donor substrate UDP-galactofuranose. It is not able to use beta-D-glucopyranoside isomers.1 Publication

Pathwayi: lipopolysaccharide biosynthesis

This protein is involved in the pathway lipopolysaccharide biosynthesis, which is part of Bacterial outer membrane biogenesis.
View all proteins of this organism that are known to be involved in the pathway lipopolysaccharide biosynthesis and in Bacterial outer membrane biogenesis.

GO - Molecular functioni

  • lipopolysaccharide-1,6-galactosyltransferase activity Source: EcoCyc

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Transferase

Keywords - Biological processi

Lipopolysaccharide biosynthesis

Enzyme and pathway databases

BioCyciEcoCyc:EG11983-MONOMER.
ECOL316407:JW2019-MONOMER.
MetaCyc:EG11983-MONOMER.
UniPathwayiUPA00030.

Names & Taxonomyi

Protein namesi
Recommended name:
Beta-1,6-galactofuranosyltransferase WbbI (EC:2.4.1.-)
Alternative name(s):
D-Galf:alpha-D-Glc beta-1,6-galactofuranosyltransferase
GalF transferase
Gene namesi
Name:wbbI
Synonyms:yefG
Ordered Locus Names:b2034, JW2019
OrganismiEscherichia coli (strain K12)
Taxonomic identifieri83333 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeEscherichia
Proteomesi
  • UP000000318 Componenti: Chromosome
  • UP000000625 Componenti: Chromosome

Organism-specific databases

EcoGeneiEG11983. yefG.

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 330330Beta-1,6-galactofuranosyltransferase WbbIPRO_0000169120Add
BLAST

Proteomic databases

EPDiP37749.
PaxDbiP37749.
PRIDEiP37749.

Interactioni

Protein-protein interaction databases

BioGridi4261355. 260 interactions.
IntActiP37749. 2 interactions.
STRINGi511145.b2034.

Structurei

3D structure databases

ProteinModelPortaliP37749.
SMRiP37749. Positions 50-324.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Phylogenomic databases

eggNOGiENOG4105GH9. Bacteria.
ENOG4111KQ1. LUCA.
OMAiTHTIEPW.
OrthoDBiEOG6N6861.

Family and domain databases

InterProiIPR016503. UDP-Galfuran_transf.
[Graphical view]
PIRSFiPIRSF007023. UDP-Galf_transf. 1 hit.

Sequencei

Sequence statusi: Complete.

P37749-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MYFLNDLNFS RRDAGFKARK DALDIASDYE NISVVNIPLW GGVVQRIISS
60 70 80 90 100
VKLSTFLCGL ENKDVLIFNF PMAKPFWHIL SFFHRLLKFR IVPLIHDIDE
110 120 130 140 150
LRGGGGSDSV RLATCDMVIS HNPQMTKYLS KYMSQDKIKD IKIFDYLVSS
160 170 180 190 200
DVEHRDVTDK QRGVIYAGNL SRHKCSFIYT EGCDFTLFGV NYENKDNPKY
210 220 230 240 250
LGSFDAQSPE KINLPGMQFG LIWDGDSVET CSGAFGDYLK FNNPHKTSLY
260 270 280 290 300
LSMELPVFIW DKAALADFIV DNRIGYAVGS IKEMQEIVDS MTIETYKQIS
310 320 330
ENTKIISQKI RTGSYFRDVL EEVIDDLKTR
Length:330
Mass (Da):37,757
Last modified:October 1, 1994 - v1
Checksum:i036A9C3523424BEF
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U03041 Genomic DNA. Translation: AAC31634.1.
U09876 Genomic DNA. Translation: AAB88405.1.
U00096 Genomic DNA. Translation: AAC75095.1.
AP009048 Genomic DNA. Translation: BAA15876.1.
PIRiI69645.
RefSeqiNP_416538.1. NC_000913.3.
WP_001407542.1. NZ_LN832404.1.

Genome annotation databases

EnsemblBacteriaiAAC75095; AAC75095; b2034.
BAA15876; BAA15876; BAA15876.
GeneIDi947041.
KEGGiecj:JW2019.
eco:b2034.
PATRICi32119401. VBIEscCol129921_2110.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U03041 Genomic DNA. Translation: AAC31634.1.
U09876 Genomic DNA. Translation: AAB88405.1.
U00096 Genomic DNA. Translation: AAC75095.1.
AP009048 Genomic DNA. Translation: BAA15876.1.
PIRiI69645.
RefSeqiNP_416538.1. NC_000913.3.
WP_001407542.1. NZ_LN832404.1.

3D structure databases

ProteinModelPortaliP37749.
SMRiP37749. Positions 50-324.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi4261355. 260 interactions.
IntActiP37749. 2 interactions.
STRINGi511145.b2034.

Proteomic databases

EPDiP37749.
PaxDbiP37749.
PRIDEiP37749.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAC75095; AAC75095; b2034.
BAA15876; BAA15876; BAA15876.
GeneIDi947041.
KEGGiecj:JW2019.
eco:b2034.
PATRICi32119401. VBIEscCol129921_2110.

Organism-specific databases

EchoBASEiEB1926.
EcoGeneiEG11983. yefG.

Phylogenomic databases

eggNOGiENOG4105GH9. Bacteria.
ENOG4111KQ1. LUCA.
OMAiTHTIEPW.
OrthoDBiEOG6N6861.

Enzyme and pathway databases

UniPathwayiUPA00030.
BioCyciEcoCyc:EG11983-MONOMER.
ECOL316407:JW2019-MONOMER.
MetaCyc:EG11983-MONOMER.

Miscellaneous databases

PROiP37749.

Family and domain databases

InterProiIPR016503. UDP-Galfuran_transf.
[Graphical view]
PIRSFiPIRSF007023. UDP-Galf_transf. 1 hit.
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. "Genetic analysis of the O-specific lipopolysaccharide biosynthesis region (rfb) of Escherichia coli K-12 W3110: identification of genes that confer group 6 specificity to Shigella flexneri serotypes Y and 4a."
    Yao Z., Valvano M.A.
    J. Bacteriol. 176:4133-4143(1994) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
    Strain: K12 / W3110 / ATCC 27325 / DSM 5911.
  2. "Structure of the O antigen of Escherichia coli K-12 and the sequence of its rfb gene cluster."
    Stevenson G., Neal B., Liu D., Hobbs M., Packer N.H., Batley M., Redmond J.W., Lindquist L., Reeves P.R.
    J. Bacteriol. 176:4144-4156(1994) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
    Strain: K12 / WG1.
  3. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: K12 / W3110 / ATCC 27325 / DSM 5911.
  4. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: K12 / MG1655 / ATCC 47076.
  5. "Highly accurate genome sequences of Escherichia coli K-12 strains MG1655 and W3110."
    Hayashi K., Morooka N., Yamamoto Y., Fujita K., Isono K., Choi S., Ohtsubo E., Baba T., Wanner B.L., Mori H., Horiuchi T.
    Mol. Syst. Biol. 2:E1-E5(2006) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: K12 / W3110 / ATCC 27325 / DSM 5911.
  6. "Expression and initial characterization of WbbI, a putative D-Galf:alpha-D-Glc beta-1,6-galactofuranosyltransferase from Escherichia coli K-12."
    Wing C., Errey J.C., Mukhopadhyay B., Blanchard J.S., Field R.A.
    Org. Biomol. Chem. 4:3945-3950(2006) [PubMed] [Europe PMC] [Abstract]
    Cited for: FUNCTION AS A GALACTOFURANOSYLTRANSFERASE, SUBSTRATE SPECIFICITY.

Entry informationi

Entry nameiWBBI_ECOLI
AccessioniPrimary (citable) accession number: P37749
Entry historyi
Integrated into UniProtKB/Swiss-Prot: October 1, 1994
Last sequence update: October 1, 1994
Last modified: March 16, 2016
This is version 108 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Escherichia coli
    Escherichia coli (strain K12): entries and cross-references to EcoGene
  2. PATHWAY comments
    Index of metabolic and biosynthesis pathways

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.