Reviewed, UniProtKB/Swiss-Prot P37715 (LYS_ASTRU)

Names and origin

Protein names	Recommended name:     Lysozyme     EC=3.2.1.17 Alternative name(s):     1,4-beta-N-acetylmuramidase
Organism	Asterias rubens (Common European starfish) (Asterias vulgaris)
Taxonomic identifier	7604 [NCBI]
Taxonomic lineage	Eukaryota › Metazoa › Echinodermata › Eleutherozoa › Asterozoa › Asteroidea › Forcipulatacea › Forcipulatida › Asteriidae › Asterias

Protein attributes

Sequence length	25 AA.
Sequence status	Fragment.
Sequence processing	The displayed sequence is not processed.
Protein existence	Evidence at protein level.

General annotation (Comments)

Catalytic activity	Hydrolysis of (1->4)-beta-linkages between N-acetylmuramic acid and N-acetyl-D-glucosamine residues in a peptidoglycan and between N-acetyl-D-glucosamine residues in chitodextrins.
Sequence similarities	Belongs to the glycosyl hydrolase 22 family.

Ontologies

Keywords
Molecular function	Antimicrobial Bacteriolytic enzyme Glycosidase Hydrolase
Technical term	Direct protein sequencing
Gene Ontology (GO)
Biological process	cytolysis Inferred from electronic annotation. Source: UniProtKB-KW defense response to bacterium Inferred from electronic annotation. Source: UniProtKB-KW metabolic process Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	lysozyme activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – ›25	›25	Lysozyme		PRO_0000208877
Experimental info
	Non-terminal residue	25	1

Sequences

	Sequence		Length	Mass (Da)
	P37715-1 [UniParc]. Last modified October 1, 1994. Version 1. Checksum: 6FA1D6BE87C5BE18	FASTA	25	2,569
	10 20 SGPVPSGCLR CICVVESGXR MPNPV

References

[1]	"The losozyme from Asterias rubens." Jolles J., Jolles P. Eur. J. Biochem. 54:19-23(1975) [PubMed: 1149747] [Abstract] Cited for: PROTEIN SEQUENCE.

Cross-references

Sequence databases
PIR	A11762.
3D structure databases
ModBase	Search...
Protein family/group databases
CAZy	GH22. Glycoside Hydrolase Family 22.
Enzyme and pathway databases
BRENDA	3.2.1.17. 74124.
Family and domain databases
InterPro	IPR019799. Glyco_hydro_22_CS. [Graphical view]
PROSITE	PS00128. LACTALBUMIN_LYSOZYME_1. Partial match. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

LYS_ASTRU

Accession

Primary (citable) accession number: P37715

Entry history

Integrated into UniProtKB/Swiss-Prot:	October 1, 1994
Last sequence update:	October 1, 1994
Last modified:	June 16, 2009
This is version 38 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)