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P37701 (GUN2_CLOJO) Reviewed, UniProtKB/Swiss-Prot

Last modified February 19, 2014. Version 71. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Endoglucanase 2

EC=3.2.1.4
Alternative name(s):
Cellulase 2
Endo-1,4-beta-glucanase 2
Gene names
Name:celB
OrganismClostridium josui
Taxonomic identifier1499 [NCBI]
Taxonomic lineageBacteriaFirmicutesClostridiaClostridialesClostridiaceaeClostridium

Protein attributes

Sequence length460 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is further processed into a mature form.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

Endohydrolysis of (1->4)-beta-D-glucosidic linkages in cellulose, lichenin and cereal beta-D-glucans.

Sequence similarities

Belongs to the glycosyl hydrolase 8 (cellulase D) family.

Ontologies

Keywords
   Biological processCarbohydrate metabolism
Cellulose degradation
Polysaccharide degradation
   DomainSignal
   Molecular functionGlycosidase
Hydrolase
Gene Ontology (GO)
   Biological_processcellulose catabolic process

Inferred from electronic annotation. Source: UniProtKB-KW

   Molecular_functioncellulase activity

Inferred from electronic annotation. Source: UniProtKB-EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Signal peptide1 – 3232 Potential
Chain33 – 460428Endoglucanase 2
PRO_0000007934

Sites

Active site991Proton donor By similarity
Active site1551Nucleophile Potential

Sequences

Sequence LengthMass (Da)Tools
P37701 [UniParc].

Last modified October 1, 1994. Version 1.
Checksum: 65EEAABCD82B7BD4

FASTA46050,599
        10         20         30         40         50         60 
MIKGSSLKRI KSLVMMAIFS VSIITTAIVS SAADQIPFPY NATYPYGAYS CLADSQSSAN 

        70         80         90        100        110        120 
NLLKSEWEQW KSAHITSNGA RGYKRVQRDA STNYDTVSEG LGYGMLLAVY FGEQQLFDDL 

       130        140        150        160        170        180 
YRYVKVFLNS NGLMSWRIDA NGNIMGQNAI GAATDADEDI AVSLVFAHKK WGTSGGFNYQ 

       190        200        210        220        230        240 
TEAKNYINNI YNKMVEPGTY VLKPGDMWGG SDVTNPSYFA PAWYRIFADF TGNSGWINVA 

       250        260        270        280        290        300 
NKCYEIADKA RNSNTGLVPD WCTANGTPAS GQGYDFYYDA IRYQWRTAID YSWYGTAKAK 

       310        320        330        340        350        360 
THCDAISNFF KNIGYPNIKD GYTLSGSQIS ANHTATFVSC AAAAAMTGTD ATYAKNIYNE 

       370        380        390        400        410        420 
CVKVKDTGNY TYFGNTLRMM ILLYTTGNFP NLYSYSSQPQ QGLKGDVNND GAIDALDIAA 

       430        440        450        460 
LKKAILTQST SNINLTNADM NNDGNIDAID FAQLKVKLLN 

« Hide

References

[1]Fujino T., Karita S., Ohmiya K.
Submitted (JUL-1993) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
D16670 Genomic DNA. Translation: BAA04078.1.
PIRI40799.

3D structure databases

ProteinModelPortalP37701.
SMRP37701. Positions 39-391.
ModBaseSearch...
MobiDBSearch...

Protein family/group databases

CAZyGH8. Glycoside Hydrolase Family 8.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Family and domain databases

Gene3D1.10.1330.10. 1 hit.
1.50.10.10. 1 hit.
InterProIPR008928. 6-hairpin_glycosidase-like.
IPR012341. 6hp_glycosidase.
IPR016134. Cellulos_enz_dockerin_1.
IPR002105. Cellulos_enz_dockerin_1_Ca-bd.
IPR018242. Dockerin_1.
IPR018247. EF_Hand_1_Ca_BS.
IPR002037. Glyco_hydro_8.
IPR019834. Glyco_hydro_8_CS.
[Graphical view]
PfamPF00404. Dockerin_1. 2 hits.
PF01270. Glyco_hydro_8. 1 hit.
[Graphical view]
PRINTSPR00735. GLHYDRLASE8.
SUPFAMSSF48208. SSF48208. 1 hit.
SSF63446. SSF63446. 1 hit.
PROSITEPS00448. CLOS_CELLULOSOME_RPT. 1 hit.
PS00018. EF_HAND_1. 2 hits.
PS00812. GLYCOSYL_HYDROL_F8. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameGUN2_CLOJO
AccessionPrimary (citable) accession number: P37701
Entry history
Integrated into UniProtKB/Swiss-Prot: October 1, 1994
Last sequence update: October 1, 1994
Last modified: February 19, 2014
This is version 71 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Glycosyl hydrolases

Classification of glycosyl hydrolase families and list of entries