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Protein

Putative L-ribulose-5-phosphate 3-epimerase SgbU

Gene

sgbU

Organism
Escherichia coli (strain K12)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Protein inferred from homologyi

Functioni

Catalyzes the isomerization of L-xylulose-5-phosphate to L-ribulose-5-phosphate (Potential). May be involved in the utilization of 2,3-diketo-L-gulonate.Curated

Catalytic activityi

L-ribulose 5-phosphate = L-xylulose 5-phosphate.

GO - Molecular functioni

GO - Biological processi

  • DNA repair Source: InterPro
  • L-lyxose metabolic process Source: EcoCyc

Keywordsi

Molecular functionIsomerase
Biological processCarbohydrate metabolism

Enzyme and pathway databases

BioCyciEcoCyc:EG12286-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Putative L-ribulose-5-phosphate 3-epimerase SgbU (EC:5.1.3.22)
Alternative name(s):
L-xylulose-5-phosphate 3-epimerase
Gene namesi
Name:sgbU
Synonyms:yiaR
Ordered Locus Names:b3582, JW5650
OrganismiEscherichia coli (strain K12)
Taxonomic identifieri83333 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesEnterobacteriaceaeEscherichia
Proteomesi
  • UP000000318 Componenti: Chromosome
  • UP000000625 Componenti: Chromosome

Organism-specific databases

EcoGeneiEG12286. sgbU.

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000977181 – 286Putative L-ribulose-5-phosphate 3-epimerase SgbUAdd BLAST286

Proteomic databases

PaxDbiP37679.
PRIDEiP37679.

Interactioni

Protein-protein interaction databases

BioGridi4259345. 3 interactors.
STRINGi316385.ECDH10B_3763.

Structurei

3D structure databases

ProteinModelPortaliP37679.
SMRiP37679.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

eggNOGiENOG41064BZ. Bacteria.
COG3623. LUCA.
HOGENOMiHOG000126090.
InParanoidiP37679.
KOiK03082.
PhylomeDBiP37679.

Family and domain databases

CDDicd00019. AP2Ec. 1 hit.
InterProiView protein in InterPro
IPR001719. AP_endonuc_2.
IPR004560. L-Ru-5P_3-Epase.
IPR036237. Xyl_isomerase-like_sf.
IPR013022. Xyl_isomerase-like_TIM-brl.
PfamiView protein in Pfam
PF01261. AP_endonuc_2. 1 hit.
SUPFAMiSSF51658. SSF51658. 1 hit.
TIGRFAMsiTIGR00542. hxl6Piso_put. 1 hit.

Sequencei

Sequence statusi: Complete.

P37679-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MRNHQLGIYE KALAKDLSWP ERLVLAKSCG FDFVEMSVDE TDERLSRLDW
60 70 80 90 100
SAAQRTSLVA AMIETGVGIP SMCLSAHRRF PFGSRDEAVR ERAREIMSKA
110 120 130 140 150
IRLARDLGIR TIQLAGYDVY YEDHDEGTRQ RFAEGLAWAV EQAAASQVML
160 170 180 190 200
AVEIMDTAFM NSISKWKKWD EMLASPWFTV YPDVGNLSAW GNDVPAELKL
210 220 230 240 250
GIDRIAAIHL KDTQPVTGQS PGQFRDVPFG EGCVDFVGIF KTLHKLNYRG
260 270 280
SFLIEMWTEK AKEPVLEIIQ ARRWIEARMQ EAGFIC
Length:286
Mass (Da):32,455
Last modified:July 15, 1999 - v2
Checksum:i4C849F575E937BF9
GO

Sequence cautioni

The sequence AAB18559 differs from that shown. Reason: Erroneous initiation. Translation N-terminally shortened.Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U00039 Genomic DNA. Translation: AAB18559.1. Different initiation.
U00096 Genomic DNA. Translation: AAC76606.2.
AP009048 Genomic DNA. Translation: BAE77711.1.
PIRiS47803.
RefSeqiNP_418039.2. NC_000913.3.
WP_001350555.1. NZ_LN832404.1.

Genome annotation databases

EnsemblBacteriaiAAC76606; AAC76606; b3582.
BAE77711; BAE77711; BAE77711.
GeneIDi948100.
KEGGiecj:JW5650.
eco:b3582.
PATRICifig|511145.12.peg.3697.

Similar proteinsi

Entry informationi

Entry nameiSGBU_ECOLI
AccessioniPrimary (citable) accession number: P37679
Secondary accession number(s): Q2M7P5
Entry historyiIntegrated into UniProtKB/Swiss-Prot: October 1, 1994
Last sequence update: July 15, 1999
Last modified: October 25, 2017
This is version 120 of the entry and version 2 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Escherichia coli
    Escherichia coli (strain K12): entries and cross-references to EcoGene
  2. SIMILARITY comments
    Index of protein domains and families