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Protein

Putative L-ribulose-5-phosphate 3-epimerase SgbU

Gene

sgbU

Organism
Escherichia coli (strain K12)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Protein inferred from homologyi

Functioni

Catalyzes the isomerization of L-xylulose-5-phosphate to L-ribulose-5-phosphate (Potential). May be involved in the utilization of 2,3-diketo-L-gulonate.Curated

Catalytic activityi

L-ribulose 5-phosphate = L-xylulose 5-phosphate.

GO - Molecular functioni

GO - Biological processi

  • L-lyxose metabolic process Source: EcoCyc
Complete GO annotation...

Keywords - Molecular functioni

Isomerase

Keywords - Biological processi

Carbohydrate metabolism

Enzyme and pathway databases

BioCyciEcoCyc:EG12286-MONOMER.
ECOL316407:JW5650-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Putative L-ribulose-5-phosphate 3-epimerase SgbU (EC:5.1.3.22)
Alternative name(s):
L-xylulose-5-phosphate 3-epimerase
Gene namesi
Name:sgbU
Synonyms:yiaR
Ordered Locus Names:b3582, JW5650
OrganismiEscherichia coli (strain K12)
Taxonomic identifieri83333 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeEscherichia
Proteomesi
  • UP000000318 Componenti: Chromosome
  • UP000000625 Componenti: Chromosome

Organism-specific databases

EcoGeneiEG12286. sgbU.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 286286Putative L-ribulose-5-phosphate 3-epimerase SgbUPRO_0000097718Add
BLAST

Proteomic databases

PaxDbiP37679.

Interactioni

Protein-protein interaction databases

BioGridi4259345. 3 interactions.
STRINGi511145.b3582.

Structurei

3D structure databases

ProteinModelPortaliP37679.
SMRiP37679. Positions 6-283.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

eggNOGiENOG41064BZ. Bacteria.
COG3623. LUCA.
HOGENOMiHOG000126090.
InParanoidiP37679.
KOiK03082.
OMAiSMCLSGH.
PhylomeDBiP37679.

Family and domain databases

Gene3Di3.20.20.150. 1 hit.
InterProiIPR004560. L-Ru-5P_3-Epase.
IPR013022. Xyl_isomerase-like_TIM-brl.
[Graphical view]
PfamiPF01261. AP_endonuc_2. 1 hit.
[Graphical view]
SUPFAMiSSF51658. SSF51658. 1 hit.
TIGRFAMsiTIGR00542. hxl6Piso_put. 1 hit.

Sequencei

Sequence statusi: Complete.

P37679-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MRNHQLGIYE KALAKDLSWP ERLVLAKSCG FDFVEMSVDE TDERLSRLDW
60 70 80 90 100
SAAQRTSLVA AMIETGVGIP SMCLSAHRRF PFGSRDEAVR ERAREIMSKA
110 120 130 140 150
IRLARDLGIR TIQLAGYDVY YEDHDEGTRQ RFAEGLAWAV EQAAASQVML
160 170 180 190 200
AVEIMDTAFM NSISKWKKWD EMLASPWFTV YPDVGNLSAW GNDVPAELKL
210 220 230 240 250
GIDRIAAIHL KDTQPVTGQS PGQFRDVPFG EGCVDFVGIF KTLHKLNYRG
260 270 280
SFLIEMWTEK AKEPVLEIIQ ARRWIEARMQ EAGFIC
Length:286
Mass (Da):32,455
Last modified:July 15, 1999 - v2
Checksum:i4C849F575E937BF9
GO

Sequence cautioni

The sequence AAB18559 differs from that shown. Reason: Erroneous initiation. Translation N-terminally shortened.Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U00039 Genomic DNA. Translation: AAB18559.1. Different initiation.
U00096 Genomic DNA. Translation: AAC76606.2.
AP009048 Genomic DNA. Translation: BAE77711.1.
PIRiS47803.
RefSeqiNP_418039.2. NC_000913.3.
WP_001350555.1. NZ_LN832404.1.

Genome annotation databases

EnsemblBacteriaiAAC76606; AAC76606; b3582.
BAE77711; BAE77711; BAE77711.
GeneIDi948100.
KEGGiecj:JW5650.
eco:b3582.
PATRICi32122640. VBIEscCol129921_3697.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U00039 Genomic DNA. Translation: AAB18559.1. Different initiation.
U00096 Genomic DNA. Translation: AAC76606.2.
AP009048 Genomic DNA. Translation: BAE77711.1.
PIRiS47803.
RefSeqiNP_418039.2. NC_000913.3.
WP_001350555.1. NZ_LN832404.1.

3D structure databases

ProteinModelPortaliP37679.
SMRiP37679. Positions 6-283.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi4259345. 3 interactions.
STRINGi511145.b3582.

Proteomic databases

PaxDbiP37679.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAC76606; AAC76606; b3582.
BAE77711; BAE77711; BAE77711.
GeneIDi948100.
KEGGiecj:JW5650.
eco:b3582.
PATRICi32122640. VBIEscCol129921_3697.

Organism-specific databases

EchoBASEiEB2194.
EcoGeneiEG12286. sgbU.

Phylogenomic databases

eggNOGiENOG41064BZ. Bacteria.
COG3623. LUCA.
HOGENOMiHOG000126090.
InParanoidiP37679.
KOiK03082.
OMAiSMCLSGH.
PhylomeDBiP37679.

Enzyme and pathway databases

BioCyciEcoCyc:EG12286-MONOMER.
ECOL316407:JW5650-MONOMER.

Miscellaneous databases

PROiP37679.

Family and domain databases

Gene3Di3.20.20.150. 1 hit.
InterProiIPR004560. L-Ru-5P_3-Epase.
IPR013022. Xyl_isomerase-like_TIM-brl.
[Graphical view]
PfamiPF01261. AP_endonuc_2. 1 hit.
[Graphical view]
SUPFAMiSSF51658. SSF51658. 1 hit.
TIGRFAMsiTIGR00542. hxl6Piso_put. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiSGBU_ECOLI
AccessioniPrimary (citable) accession number: P37679
Secondary accession number(s): Q2M7P5
Entry historyi
Integrated into UniProtKB/Swiss-Prot: October 1, 1994
Last sequence update: July 15, 1999
Last modified: September 7, 2016
This is version 111 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Escherichia coli
    Escherichia coli (strain K12): entries and cross-references to EcoGene
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.