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Protein

2,3-diketo-L-gulonate TRAP transporter small permease protein YiaM

Gene

yiaM

Organism
Escherichia coli (strain K12)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Part of the tripartite ATP-independent periplasmic (TRAP) transport system YiaMNO involved in the uptake of 2,3-diketo-L-gulonate.1 Publication

Caution

Was originally proposed to be a subunit from an L-xylulose uptake system, but PubMed:16385129 shows that it does not bind L- or D-xylulose.1 Publication

GO - Molecular functioni

  • carbohydrate transmembrane transporter activity Source: EcoCyc

GO - Biological processi

  • carbohydrate transmembrane transport Source: EcoCyc

Keywordsi

Biological processTransport

Enzyme and pathway databases

BioCyciEcoCyc:MONOMER0-422
MetaCyc:MONOMER0-422

Protein family/group databases

TCDBi2.A.56.1.2 the tripartite atp-independent periplasmic transporter (trap-t) family

Names & Taxonomyi

Protein namesi
Recommended name:
2,3-diketo-L-gulonate TRAP transporter small permease protein YiaM
Gene namesi
Name:yiaM
Ordered Locus Names:b3577, JW3549
OrganismiEscherichia coli (strain K12)
Taxonomic identifieri83333 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesEnterobacteriaceaeEscherichia
Proteomesi
  • UP000000318 Componenti: Chromosome
  • UP000000625 Componenti: Chromosome

Organism-specific databases

EcoGeneiEG12281 yiaM

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Topological domaini1 – 6CytoplasmicSequence analysis6
Transmembranei7 – 29HelicalSequence analysisAdd BLAST23
Topological domaini30 – 43PeriplasmicSequence analysisAdd BLAST14
Transmembranei44 – 66HelicalSequence analysisAdd BLAST23
Topological domaini67 – 78CytoplasmicSequence analysisAdd BLAST12
Transmembranei79 – 98HelicalSequence analysisAdd BLAST20
Topological domaini99 – 112PeriplasmicSequence analysisAdd BLAST14
Transmembranei113 – 135HelicalSequence analysisAdd BLAST23
Topological domaini136 – 157CytoplasmicSequence analysisAdd BLAST22

GO - Cellular componenti

  • integral component of membrane Source: UniProtKB-KW
  • plasma membrane Source: EcoCyc

Keywords - Cellular componenti

Cell inner membrane, Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001695951 – 1572,3-diketo-L-gulonate TRAP transporter small permease protein YiaMAdd BLAST157

Proteomic databases

PaxDbiP37674
PRIDEiP37674

Interactioni

Subunit structurei

The complex comprises the extracytoplasmic solute receptor protein YiaO, and the two transmembrane proteins YiaM and YiaN.

Protein-protein interaction databases

BioGridi4262548, 5 interactors
STRINGi316385.ECDH10B_3758

Structurei

3D structure databases

ProteinModelPortaliP37674
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiENOG4105XDZ Bacteria
COG3090 LUCA
HOGENOMiHOG000224991
InParanoidiP37674
KOiK21394
OMAiSMIWVYG
PhylomeDBiP37674

Family and domain databases

InterProiView protein in InterPro
IPR007387 TRAP_DctQ
PANTHERiPTHR35011 PTHR35011, 1 hit
PfamiView protein in Pfam
PF04290 DctQ, 1 hit
PROSITEiView protein in PROSITE
PS51257 PROKAR_LIPOPROTEIN, 1 hit

Sequencei

Sequence statusi: Complete.

P37674-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKKILEAILA INLAVLSCIV FINIILRYGF QTSILSVDEL SRYLFVWLTF
60 70 80 90 100
IGAIVAFMDN AHVQVTFLVE KLSPAWQRRV ALVTHSLILF ICGALAWGAT
110 120 130 140 150
LKTIQDWSDY SPILGLPIGL MYAACLPTSL VIAFFELRHL YQLITRSNSL

TSPPQGA
Length:157
Mass (Da):17,516
Last modified:October 1, 1994 - v1
Checksum:iE8839A3FCEB2BEDA
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U00039 Genomic DNA Translation: AAB18554.1
U00096 Genomic DNA Translation: AAC76601.1
AP009048 Genomic DNA Translation: BAE77716.1
PIRiS47798
RefSeqiNP_418034.1, NC_000913.3
WP_000721664.1, NZ_LN832404.1

Genome annotation databases

EnsemblBacteriaiAAC76601; AAC76601; b3577
BAE77716; BAE77716; BAE77716
GeneIDi948093
KEGGiecj:JW3549
eco:b3577
PATRICifig|1411691.4.peg.3135

Similar proteinsi

Entry informationi

Entry nameiYIAM_ECOLI
AccessioniPrimary (citable) accession number: P37674
Secondary accession number(s): Q2M7P0
Entry historyiIntegrated into UniProtKB/Swiss-Prot: October 1, 1994
Last sequence update: October 1, 1994
Last modified: May 23, 2018
This is version 115 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Escherichia coli
    Escherichia coli (strain K12): entries and cross-references to EcoGene
  2. SIMILARITY comments
    Index of protein domains and families
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