Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Probable lipoprotein YiaD

Gene

yiaD

Organism
Escherichia coli (strain K12)
Status
Reviewed-Annotation score: Annotation score: 4 out of 5-Experimental evidence at protein leveli

Functioni

Suppresses temperature-sensitive mutations in BamB when overexpressed.1 Publication

Enzyme and pathway databases

BioCyciEcoCyc:EG12271-MONOMER.
ECOL316407:JW5657-MONOMER.
RETL1328306-WGS:GSTH-2851-MONOMER.

Protein family/group databases

TCDBi9.B.186.1.1. the putative lipoprotein supressor of a ts bamd mutant, yiad (yiad) family.

Names & Taxonomyi

Protein namesi
Recommended name:
Probable lipoprotein YiaD
Gene namesi
Name:yiaD
Ordered Locus Names:b3552, JW5657
OrganismiEscherichia coli (strain K12)
Taxonomic identifieri83333 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeEscherichia
Proteomesi
  • UP000000318 Componenti: Chromosome
  • UP000000625 Componenti: Chromosome

Organism-specific databases

EcoGeneiEG12271. yiaD.

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei37 – 5519HelicalSequence analysisAdd
BLAST
Transmembranei62 – 8423HelicalSequence analysisAdd
BLAST

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Cell inner membrane, Cell membrane, Cell outer membrane, Membrane

Pathology & Biotechi

Disruption phenotypei

No visible phenotype.1 Publication

Mutagenesis

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Mutagenesisi116 – 1161F → A: Does not suppress BamB ts-mutants. 1 Publication
Mutagenesisi150 – 1501G → A: Partially suppresses BamB ts-mutants. 1 Publication
Mutagenesisi153 – 1531D → A: Does not suppress BamB ts-mutants. 1 Publication
Mutagenesisi156 – 1561G → A: Does not suppress BamB ts-mutants. 1 Publication
Mutagenesisi164 – 1641L → A: Partially suppresses BamB ts-mutants. 1 Publication
Mutagenesisi168 – 1681R → A: Does not suppress BamB ts-mutants. 1 Publication

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Signal peptidei1 – 2020PROSITE-ProRule annotationAdd
BLAST
Chaini21 – 219199Probable lipoprotein YiaDPRO_0000020134Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Lipidationi21 – 211N-palmitoyl cysteinePROSITE-ProRule annotation
Lipidationi21 – 211S-diacylglycerol cysteinePROSITE-ProRule annotation

Keywords - PTMi

Lipoprotein, Palmitate

Proteomic databases

PaxDbiP37665.
PRIDEiP37665.

Interactioni

Protein-protein interaction databases

IntActiP37665. 2 interactions.
STRINGi511145.b3552.

Structurei

Secondary structure

1
219
Legend: HelixTurnBeta strand
Show more details
Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Helixi82 – 9110Combined sources
Turni92 – 954Combined sources
Beta strandi98 – 1025Combined sources
Beta strandi105 – 1117Combined sources
Helixi112 – 1154Combined sources
Beta strandi116 – 1216Combined sources
Helixi125 – 14016Combined sources
Beta strandi144 – 1518Combined sources
Beta strandi153 – 1564Combined sources
Helixi158 – 17922Combined sources
Helixi183 – 1853Combined sources
Beta strandi186 – 1905Combined sources
Turni192 – 1943Combined sources
Beta strandi200 – 2023Combined sources
Helixi203 – 2097Combined sources
Beta strandi210 – 2189Combined sources

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
2K1SNMR-A79-219[»]
2N48NMR-A79-219[»]
ProteinModelPortaliP37665.
SMRiP37665. Positions 79-219.
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiP37665.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini103 – 219117OmpA-likePROSITE-ProRule annotationAdd
BLAST

Sequence similaritiesi

Belongs to the OmpA family.Curated
Contains 1 OmpA-like domain.PROSITE-ProRule annotation

Keywords - Domaini

Signal, Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiENOG4108ZG0. Bacteria.
COG2885. LUCA.
HOGENOMiHOG000189914.
InParanoidiP37665.
OMAiIGNYMDQ.
PhylomeDBiP37665.

Family and domain databases

CDDicd07185. OmpA_C-like. 1 hit.
Gene3Di3.30.1330.60. 1 hit.
InterProiIPR006664. OMP_bac.
IPR006665. OmpA-like.
IPR006690. OMPA-like_CS.
[Graphical view]
PfamiPF00691. OmpA. 1 hit.
[Graphical view]
PRINTSiPR01021. OMPADOMAIN.
SUPFAMiSSF103088. SSF103088. 1 hit.
PROSITEiPS01068. OMPA_1. 1 hit.
PS51123. OMPA_2. 1 hit.
PS51257. PROKAR_LIPOPROTEIN. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

P37665-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKKRVYLIAA VVSGALAVSG CTTNPYTGER EAGKSAIGAG LGSLVGAGIG
60 70 80 90 100
ALSSSKKDRG KGALIGAAAG AALGGGVGYY MDVQEAKLRD KMRGTGVSVT
110 120 130 140 150
RSGDNIILNM PNNVTFDSSS ATLKPAGANT LTGVAMVLKE YPKTAVNVIG
160 170 180 190 200
YTDSTGGHDL NMRLSQQRAD SVASALITQG VDASRIRTQG LGPANPIASN
210
STAEGKAQNR RVEITLSPL
Length:219
Mass (Da):22,197
Last modified:October 11, 2004 - v2
Checksum:i8EC223021B520418
GO

Sequence cautioni

The sequence M34827 differs from that shown. Reason: Frameshift at position 88. Curated

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Sequence conflicti87 – 882KL → NV in AAB18529 (PubMed:8041620).Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U00039 Genomic DNA. Translation: AAB18529.1.
U00096 Genomic DNA. Translation: AAT48190.1.
AP009048 Genomic DNA. Translation: BAE77743.1.
M34827 Genomic DNA. No translation available.
PIRiS47773.
RefSeqiWP_000747625.1. NZ_LN832404.1.
YP_026228.1. NC_000913.3.

Genome annotation databases

EnsemblBacteriaiAAT48190; AAT48190; b3552.
BAE77743; BAE77743; BAE77743.
GeneIDi948075.
KEGGiecj:JW5657.
eco:b3552.
PATRICi32122576. VBIEscCol129921_3665.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U00039 Genomic DNA. Translation: AAB18529.1.
U00096 Genomic DNA. Translation: AAT48190.1.
AP009048 Genomic DNA. Translation: BAE77743.1.
M34827 Genomic DNA. No translation available.
PIRiS47773.
RefSeqiWP_000747625.1. NZ_LN832404.1.
YP_026228.1. NC_000913.3.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
2K1SNMR-A79-219[»]
2N48NMR-A79-219[»]
ProteinModelPortaliP37665.
SMRiP37665. Positions 79-219.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

IntActiP37665. 2 interactions.
STRINGi511145.b3552.

Protein family/group databases

TCDBi9.B.186.1.1. the putative lipoprotein supressor of a ts bamd mutant, yiad (yiad) family.

Proteomic databases

PaxDbiP37665.
PRIDEiP37665.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAT48190; AAT48190; b3552.
BAE77743; BAE77743; BAE77743.
GeneIDi948075.
KEGGiecj:JW5657.
eco:b3552.
PATRICi32122576. VBIEscCol129921_3665.

Organism-specific databases

EchoBASEiEB2180.
EcoGeneiEG12271. yiaD.

Phylogenomic databases

eggNOGiENOG4108ZG0. Bacteria.
COG2885. LUCA.
HOGENOMiHOG000189914.
InParanoidiP37665.
OMAiIGNYMDQ.
PhylomeDBiP37665.

Enzyme and pathway databases

BioCyciEcoCyc:EG12271-MONOMER.
ECOL316407:JW5657-MONOMER.
RETL1328306-WGS:GSTH-2851-MONOMER.

Miscellaneous databases

EvolutionaryTraceiP37665.
PROiP37665.

Family and domain databases

CDDicd07185. OmpA_C-like. 1 hit.
Gene3Di3.30.1330.60. 1 hit.
InterProiIPR006664. OMP_bac.
IPR006665. OmpA-like.
IPR006690. OMPA-like_CS.
[Graphical view]
PfamiPF00691. OmpA. 1 hit.
[Graphical view]
PRINTSiPR01021. OMPADOMAIN.
SUPFAMiSSF103088. SSF103088. 1 hit.
PROSITEiPS01068. OMPA_1. 1 hit.
PS51123. OMPA_2. 1 hit.
PS51257. PROKAR_LIPOPROTEIN. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiYIAD_ECOLI
AccessioniPrimary (citable) accession number: P37665
Secondary accession number(s): Q2M7L3, Q6BF24
Entry historyi
Integrated into UniProtKB/Swiss-Prot: October 1, 1994
Last sequence update: October 11, 2004
Last modified: September 7, 2016
This is version 129 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Reference proteome

Documents

  1. Escherichia coli
    Escherichia coli (strain K12): entries and cross-references to EcoGene
  2. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  3. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.