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Protein

Uncharacterized MFS-type transporter YhjX

Gene

yhjX

Organism
Escherichia coli (strain K12)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

  • cellular response to nutrient levels Source: EcoCyc
  • ion transmembrane transport Source: GO_Central
Complete GO annotation...

Keywords - Biological processi

Transport

Enzyme and pathway databases

BioCyciEcoCyc:YHJX-MONOMER.
ECOL316407:JW3516-MONOMER.

Protein family/group databases

TCDBi2.A.1.11.3. the major facilitator superfamily (mfs).

Names & Taxonomyi

Protein namesi
Recommended name:
Uncharacterized MFS-type transporter YhjX
Gene namesi
Name:yhjX
Ordered Locus Names:b3547, JW3516
OrganismiEscherichia coli (strain K12)
Taxonomic identifieri83333 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesEnterobacteriaceaeEscherichia
Proteomesi
  • UP000000318 Componenti: Chromosome
  • UP000000625 Componenti: Chromosome

Organism-specific databases

EcoGeneiEG12268. yhjX.

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Topological domaini1 – 11CytoplasmicSequence analysisAdd BLAST11
Transmembranei12 – 34HelicalSequence analysisAdd BLAST23
Topological domaini35 – 43PeriplasmicSequence analysis9
Transmembranei44 – 66HelicalSequence analysisAdd BLAST23
Topological domaini67 – 72CytoplasmicSequence analysis6
Transmembranei73 – 95HelicalSequence analysisAdd BLAST23
Topological domaini96 – 99PeriplasmicSequence analysis4
Transmembranei100 – 122HelicalSequence analysisAdd BLAST23
Topological domaini123 – 134CytoplasmicSequence analysisAdd BLAST12
Transmembranei135 – 154HelicalSequence analysisAdd BLAST20
Topological domaini155 – 168PeriplasmicSequence analysisAdd BLAST14
Transmembranei169 – 186HelicalSequence analysisAdd BLAST18
Topological domaini187 – 216CytoplasmicSequence analysisAdd BLAST30
Transmembranei217 – 236HelicalSequence analysisAdd BLAST20
Topological domaini237 – 250PeriplasmicSequence analysisAdd BLAST14
Transmembranei251 – 273HelicalSequence analysisAdd BLAST23
Topological domaini274 – 279CytoplasmicSequence analysis6
Transmembranei280 – 302HelicalSequence analysisAdd BLAST23
Topological domaini303 – 306PeriplasmicSequence analysis4
Transmembranei307 – 329HelicalSequence analysisAdd BLAST23
Topological domaini330 – 341CytoplasmicSequence analysisAdd BLAST12
Transmembranei342 – 364HelicalSequence analysisAdd BLAST23
Topological domaini365 – 367PeriplasmicSequence analysis3
Transmembranei368 – 387HelicalSequence analysisAdd BLAST20
Topological domaini388 – 402CytoplasmicSequence analysisAdd BLAST15

GO - Cellular componenti

  • integral component of membrane Source: GO_Central
  • plasma membrane Source: EcoCyc
Complete GO annotation...

Keywords - Cellular componenti

Cell inner membrane, Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001695851 – 402Uncharacterized MFS-type transporter YhjXAdd BLAST402

Proteomic databases

PaxDbiP37662.
PRIDEiP37662.

Expressioni

Inductioni

Induced by the two-component regulatory system YpdA/YpdB in response to pyruvate.1 Publication

Interactioni

Protein-protein interaction databases

BioGridi4260694. 168 interactors.
DIPiDIP-12395N.
IntActiP37662. 1 interactor.
MINTiMINT-1232452.
STRINGi511145.b3547.

Structurei

3D structure databases

ProteinModelPortaliP37662.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the major facilitator superfamily.Curated

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiENOG4105FCD. Bacteria.
ENOG410XQUK. LUCA.
HOGENOMiHOG000058263.
InParanoidiP37662.
KOiK08177.
OMAiFMIWGAI.
PhylomeDBiP37662.

Family and domain databases

CDDicd06174. MFS. 1 hit.
InterProiIPR011701. MFS.
IPR020846. MFS_dom.
IPR004741. Oxa_For_antiport_fam_transptr.
[Graphical view]
PfamiPF07690. MFS_1. 1 hit.
[Graphical view]
SUPFAMiSSF103473. SSF103473. 1 hit.
TIGRFAMsiTIGR00890. 2A0111. 1 hit.
PROSITEiPS50850. MFS. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P37662-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTPSNYQRTR WLTLIGTIIT QFALGSVYTW SLFNGALSAK LDAPVSQVAF
60 70 80 90 100
SFGLLSLGLA ISSSVAGKLQ ERFGVKRVTM ASGILLGLGF FLTAHSDNLM
110 120 130 140 150
MLWLSAGVLV GLADGAGYLL TLSNCVKWFP ERKGLISAFA IGSYGLGSLG
160 170 180 190 200
FKFIDTQLLE TVGLEKTFVI WGAIALLMIV FGATLMKDAP KQEVKTSNGV
210 220 230 240 250
VEKDYTLAES MRKPQYWMLA VMFLTACMSG LYVIGVAKDI AQSLAHLDVV
260 270 280 290 300
SAANAVTVIS IANLSGRLVL GILSDKIARI RVITIGQVIS LVGMAALLFA
310 320 330 340 350
PLNAVTFFAA IACVAFNFGG TITVFPSLVS EFFGLNNLAK NYGVIYLGFG
360 370 380 390 400
IGSICGSIIA SLFGGFYVTF YVIFALLILS LALSTTIRQP EQKMLREAHG

SL
Length:402
Mass (Da):42,951
Last modified:October 1, 1994 - v1
Checksum:iFD2A2189B5873688
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U00039 Genomic DNA. Translation: AAB18524.1.
U00096 Genomic DNA. Translation: AAC76571.1.
AP009048 Genomic DNA. Translation: BAE77748.1.
PIRiS47768.
RefSeqiNP_418003.1. NC_000913.3.
WP_000189019.1. NZ_LN832404.1.

Genome annotation databases

EnsemblBacteriaiAAC76571; AAC76571; b3547.
BAE77748; BAE77748; BAE77748.
GeneIDi948066.
KEGGiecj:JW3516.
eco:b3547.
PATRICi32122566. VBIEscCol129921_3660.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U00039 Genomic DNA. Translation: AAB18524.1.
U00096 Genomic DNA. Translation: AAC76571.1.
AP009048 Genomic DNA. Translation: BAE77748.1.
PIRiS47768.
RefSeqiNP_418003.1. NC_000913.3.
WP_000189019.1. NZ_LN832404.1.

3D structure databases

ProteinModelPortaliP37662.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi4260694. 168 interactors.
DIPiDIP-12395N.
IntActiP37662. 1 interactor.
MINTiMINT-1232452.
STRINGi511145.b3547.

Protein family/group databases

TCDBi2.A.1.11.3. the major facilitator superfamily (mfs).

Proteomic databases

PaxDbiP37662.
PRIDEiP37662.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAC76571; AAC76571; b3547.
BAE77748; BAE77748; BAE77748.
GeneIDi948066.
KEGGiecj:JW3516.
eco:b3547.
PATRICi32122566. VBIEscCol129921_3660.

Organism-specific databases

EchoBASEiEB2177.
EcoGeneiEG12268. yhjX.

Phylogenomic databases

eggNOGiENOG4105FCD. Bacteria.
ENOG410XQUK. LUCA.
HOGENOMiHOG000058263.
InParanoidiP37662.
KOiK08177.
OMAiFMIWGAI.
PhylomeDBiP37662.

Enzyme and pathway databases

BioCyciEcoCyc:YHJX-MONOMER.
ECOL316407:JW3516-MONOMER.

Miscellaneous databases

PROiP37662.

Family and domain databases

CDDicd06174. MFS. 1 hit.
InterProiIPR011701. MFS.
IPR020846. MFS_dom.
IPR004741. Oxa_For_antiport_fam_transptr.
[Graphical view]
PfamiPF07690. MFS_1. 1 hit.
[Graphical view]
SUPFAMiSSF103473. SSF103473. 1 hit.
TIGRFAMsiTIGR00890. 2A0111. 1 hit.
PROSITEiPS50850. MFS. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiYHJX_ECOLI
AccessioniPrimary (citable) accession number: P37662
Secondary accession number(s): Q2M7K8
Entry historyi
Integrated into UniProtKB/Swiss-Prot: October 1, 1994
Last sequence update: October 1, 1994
Last modified: November 2, 2016
This is version 124 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Escherichia coli
    Escherichia coli (strain K12): entries and cross-references to EcoGene
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.