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Protein

Uncharacterized MFS-type transporter YhjX

Gene

yhjX

Organism
Escherichia coli (strain K12)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

  • cellular response to nutrient levels Source: EcoCyc
  • ion transmembrane transport Source: GO_Central
Complete GO annotation...

Keywords - Biological processi

Transport

Enzyme and pathway databases

BioCyciEcoCyc:YHJX-MONOMER.
ECOL316407:JW3516-MONOMER.

Protein family/group databases

TCDBi2.A.1.11.3. the major facilitator superfamily (mfs).

Names & Taxonomyi

Protein namesi
Recommended name:
Uncharacterized MFS-type transporter YhjX
Gene namesi
Name:yhjX
Ordered Locus Names:b3547, JW3516
OrganismiEscherichia coli (strain K12)
Taxonomic identifieri83333 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeEscherichia
Proteomesi
  • UP000000318 Componenti: Chromosome
  • UP000000625 Componenti: Chromosome

Organism-specific databases

EcoGeneiEG12268. yhjX.

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Topological domaini1 – 1111CytoplasmicSequence analysisAdd
BLAST
Transmembranei12 – 3423HelicalSequence analysisAdd
BLAST
Topological domaini35 – 439PeriplasmicSequence analysis
Transmembranei44 – 6623HelicalSequence analysisAdd
BLAST
Topological domaini67 – 726CytoplasmicSequence analysis
Transmembranei73 – 9523HelicalSequence analysisAdd
BLAST
Topological domaini96 – 994PeriplasmicSequence analysis
Transmembranei100 – 12223HelicalSequence analysisAdd
BLAST
Topological domaini123 – 13412CytoplasmicSequence analysisAdd
BLAST
Transmembranei135 – 15420HelicalSequence analysisAdd
BLAST
Topological domaini155 – 16814PeriplasmicSequence analysisAdd
BLAST
Transmembranei169 – 18618HelicalSequence analysisAdd
BLAST
Topological domaini187 – 21630CytoplasmicSequence analysisAdd
BLAST
Transmembranei217 – 23620HelicalSequence analysisAdd
BLAST
Topological domaini237 – 25014PeriplasmicSequence analysisAdd
BLAST
Transmembranei251 – 27323HelicalSequence analysisAdd
BLAST
Topological domaini274 – 2796CytoplasmicSequence analysis
Transmembranei280 – 30223HelicalSequence analysisAdd
BLAST
Topological domaini303 – 3064PeriplasmicSequence analysis
Transmembranei307 – 32923HelicalSequence analysisAdd
BLAST
Topological domaini330 – 34112CytoplasmicSequence analysisAdd
BLAST
Transmembranei342 – 36423HelicalSequence analysisAdd
BLAST
Topological domaini365 – 3673PeriplasmicSequence analysis
Transmembranei368 – 38720HelicalSequence analysisAdd
BLAST
Topological domaini388 – 40215CytoplasmicSequence analysisAdd
BLAST

GO - Cellular componenti

  • integral component of membrane Source: GO_Central
  • plasma membrane Source: EcoCyc
Complete GO annotation...

Keywords - Cellular componenti

Cell inner membrane, Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 402402Uncharacterized MFS-type transporter YhjXPRO_0000169585Add
BLAST

Proteomic databases

PaxDbiP37662.

Expressioni

Inductioni

Induced by the two-component regulatory system YpdA/YpdB in response to pyruvate.1 Publication

Interactioni

Protein-protein interaction databases

BioGridi4260694. 168 interactions.
DIPiDIP-12395N.
IntActiP37662. 1 interaction.
MINTiMINT-1232452.
STRINGi511145.b3547.

Structurei

3D structure databases

ProteinModelPortaliP37662.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the major facilitator superfamily.Curated

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiENOG4105FCD. Bacteria.
ENOG410XQUK. LUCA.
HOGENOMiHOG000058263.
InParanoidiP37662.
KOiK08177.
OMAiFMIWGAI.
PhylomeDBiP37662.

Family and domain databases

CDDicd06174. MFS. 1 hit.
InterProiIPR011701. MFS.
IPR020846. MFS_dom.
IPR004741. Oxa_For_antiport_fam_transptr.
[Graphical view]
PfamiPF07690. MFS_1. 1 hit.
[Graphical view]
SUPFAMiSSF103473. SSF103473. 1 hit.
TIGRFAMsiTIGR00890. 2A0111. 1 hit.
PROSITEiPS50850. MFS. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P37662-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTPSNYQRTR WLTLIGTIIT QFALGSVYTW SLFNGALSAK LDAPVSQVAF
60 70 80 90 100
SFGLLSLGLA ISSSVAGKLQ ERFGVKRVTM ASGILLGLGF FLTAHSDNLM
110 120 130 140 150
MLWLSAGVLV GLADGAGYLL TLSNCVKWFP ERKGLISAFA IGSYGLGSLG
160 170 180 190 200
FKFIDTQLLE TVGLEKTFVI WGAIALLMIV FGATLMKDAP KQEVKTSNGV
210 220 230 240 250
VEKDYTLAES MRKPQYWMLA VMFLTACMSG LYVIGVAKDI AQSLAHLDVV
260 270 280 290 300
SAANAVTVIS IANLSGRLVL GILSDKIARI RVITIGQVIS LVGMAALLFA
310 320 330 340 350
PLNAVTFFAA IACVAFNFGG TITVFPSLVS EFFGLNNLAK NYGVIYLGFG
360 370 380 390 400
IGSICGSIIA SLFGGFYVTF YVIFALLILS LALSTTIRQP EQKMLREAHG

SL
Length:402
Mass (Da):42,951
Last modified:October 1, 1994 - v1
Checksum:iFD2A2189B5873688
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U00039 Genomic DNA. Translation: AAB18524.1.
U00096 Genomic DNA. Translation: AAC76571.1.
AP009048 Genomic DNA. Translation: BAE77748.1.
PIRiS47768.
RefSeqiNP_418003.1. NC_000913.3.
WP_000189019.1. NZ_LN832404.1.

Genome annotation databases

EnsemblBacteriaiAAC76571; AAC76571; b3547.
BAE77748; BAE77748; BAE77748.
GeneIDi948066.
KEGGiecj:JW3516.
eco:b3547.
PATRICi32122566. VBIEscCol129921_3660.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U00039 Genomic DNA. Translation: AAB18524.1.
U00096 Genomic DNA. Translation: AAC76571.1.
AP009048 Genomic DNA. Translation: BAE77748.1.
PIRiS47768.
RefSeqiNP_418003.1. NC_000913.3.
WP_000189019.1. NZ_LN832404.1.

3D structure databases

ProteinModelPortaliP37662.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi4260694. 168 interactions.
DIPiDIP-12395N.
IntActiP37662. 1 interaction.
MINTiMINT-1232452.
STRINGi511145.b3547.

Protein family/group databases

TCDBi2.A.1.11.3. the major facilitator superfamily (mfs).

Proteomic databases

PaxDbiP37662.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAC76571; AAC76571; b3547.
BAE77748; BAE77748; BAE77748.
GeneIDi948066.
KEGGiecj:JW3516.
eco:b3547.
PATRICi32122566. VBIEscCol129921_3660.

Organism-specific databases

EchoBASEiEB2177.
EcoGeneiEG12268. yhjX.

Phylogenomic databases

eggNOGiENOG4105FCD. Bacteria.
ENOG410XQUK. LUCA.
HOGENOMiHOG000058263.
InParanoidiP37662.
KOiK08177.
OMAiFMIWGAI.
PhylomeDBiP37662.

Enzyme and pathway databases

BioCyciEcoCyc:YHJX-MONOMER.
ECOL316407:JW3516-MONOMER.

Miscellaneous databases

PROiP37662.

Family and domain databases

CDDicd06174. MFS. 1 hit.
InterProiIPR011701. MFS.
IPR020846. MFS_dom.
IPR004741. Oxa_For_antiport_fam_transptr.
[Graphical view]
PfamiPF07690. MFS_1. 1 hit.
[Graphical view]
SUPFAMiSSF103473. SSF103473. 1 hit.
TIGRFAMsiTIGR00890. 2A0111. 1 hit.
PROSITEiPS50850. MFS. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiYHJX_ECOLI
AccessioniPrimary (citable) accession number: P37662
Secondary accession number(s): Q2M7K8
Entry historyi
Integrated into UniProtKB/Swiss-Prot: October 1, 1994
Last sequence update: October 1, 1994
Last modified: September 7, 2016
This is version 122 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Escherichia coli
    Escherichia coli (strain K12): entries and cross-references to EcoGene
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.