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Protein

Inner membrane metabolite transport protein YhjE

Gene

yhjE

Organism
Escherichia coli (strain K12)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

Complete GO annotation...

Keywords - Biological processi

Transport

Enzyme and pathway databases

BioCyciEcoCyc:YHJE-MONOMER.
ECOL316407:JW3491-MONOMER.

Protein family/group databases

TCDBi2.A.1.6.10. the major facilitator superfamily (mfs).

Names & Taxonomyi

Protein namesi
Recommended name:
Inner membrane metabolite transport protein YhjE
Gene namesi
Name:yhjE
Ordered Locus Names:b3523, JW3491
OrganismiEscherichia coli (strain K12)
Taxonomic identifieri83333 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesEnterobacteriaceaeEscherichia
Proteomesi
  • UP000000318 Componenti: Chromosome
  • UP000000625 Componenti: Chromosome

Organism-specific databases

EcoGeneiEG12249. yhjE.

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Topological domaini1 – 34CytoplasmicSequence analysisAdd BLAST34
Transmembranei35 – 55Helical; Name=1Sequence analysisAdd BLAST21
Topological domaini56 – 66PeriplasmicSequence analysisAdd BLAST11
Transmembranei67 – 87Helical; Name=2Sequence analysisAdd BLAST21
Topological domaini88 – 108CytoplasmicSequence analysisAdd BLAST21
Transmembranei109 – 129Helical; Name=3Sequence analysisAdd BLAST21
Transmembranei130 – 150Helical; Name=4Sequence analysisAdd BLAST21
Topological domaini151 – 167CytoplasmicSequence analysisAdd BLAST17
Transmembranei168 – 188Helical; Name=5Sequence analysisAdd BLAST21
Topological domaini189 – 192PeriplasmicSequence analysis4
Transmembranei193 – 213Helical; Name=6Sequence analysisAdd BLAST21
Topological domaini214 – 248CytoplasmicSequence analysisAdd BLAST35
Transmembranei249 – 269Helical; Name=7Sequence analysisAdd BLAST21
Topological domaini270 – 289PeriplasmicSequence analysisAdd BLAST20
Transmembranei290 – 310Helical; Name=8Sequence analysisAdd BLAST21
Topological domaini311 – 320CytoplasmicSequence analysis10
Transmembranei321 – 341Helical; Name=9Sequence analysisAdd BLAST21
Topological domaini342 – 345PeriplasmicSequence analysis4
Transmembranei346 – 366Helical; Name=10Sequence analysisAdd BLAST21
Topological domaini367 – 384CytoplasmicSequence analysisAdd BLAST18
Transmembranei385 – 405Helical; Name=11Sequence analysisAdd BLAST21
Topological domaini406 – 410PeriplasmicSequence analysis5
Transmembranei411 – 431Helical; Name=12Sequence analysisAdd BLAST21
Topological domaini432 – 440CytoplasmicSequence analysis9

GO - Cellular componenti

  • integral component of membrane Source: UniProtKB-KW
  • plasma membrane Source: EcoCyc
Complete GO annotation...

Keywords - Cellular componenti

Cell inner membrane, Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000504861 – 440Inner membrane metabolite transport protein YhjEAdd BLAST440

Proteomic databases

PaxDbiP37643.
PRIDEiP37643.

Interactioni

Protein-protein interaction databases

BioGridi4262156. 331 interactors.
STRINGi511145.b3523.

Structurei

3D structure databases

ProteinModelPortaliP37643.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiENOG4105CSH. Bacteria.
ENOG410XP7I. LUCA.
HOGENOMiHOG000141611.
InParanoidiP37643.
OMAiSTYAQAP.
PhylomeDBiP37643.

Family and domain databases

CDDicd06174. MFS. 1 hit.
InterProiIPR004736. Cit_H_symport.
IPR011701. MFS.
IPR020846. MFS_dom.
IPR005828. MFS_sugar_transport-like.
IPR005829. Sugar_transporter_CS.
[Graphical view]
PfamiPF07690. MFS_1. 1 hit.
PF00083. Sugar_tr. 1 hit.
[Graphical view]
SUPFAMiSSF103473. SSF103473. 1 hit.
TIGRFAMsiTIGR00883. 2A0106. 1 hit.
PROSITEiPS50850. MFS. 1 hit.
PS00216. SUGAR_TRANSPORT_1. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P37643-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MQATATTLDH EQEYTPINSR NKVLVASLIG TAIEFFDFYI YATAAVIVFP
60 70 80 90 100
HIFFPQGDPT AATLQSLATF AIAFVARPIG SAVFGHFGDR VGRKATLVAS
110 120 130 140 150
LLTMGISTVV IGLLPGYATI GIFAPLLLAL ARFGQGLGLG GEWGGAALLA
160 170 180 190 200
TENAPPRKRA LYGSFPQLGA PIGFFFANGT FLLLSWLLTD EQFMSWGWRV
210 220 230 240 250
PFIFSAVLVI IGLYVRVSLH ESPVFEKVAK AKKQVKIPLG TLLTKHVRVT
260 270 280 290 300
VLGTFIMLAT YTLFYIMTVY SMTFSTAAAP VGLGLPRNEV LWMLMMAVIG
310 320 330 340 350
FGVMVPVAGL LADAFGRRKS MVIITTLIIL FALFAFNPLL GSGNPILVFA
360 370 380 390 400
FLLLGLSLMG LTFGPMGALL PELFPTEVRY TGASFSYNVA SILGASVAPY
410 420 430 440
IAAWLQTNYG LGAVGLYLAA MAGLTLIALL LTHETRHQSL
Length:440
Mass (Da):47,208
Last modified:October 1, 1994 - v1
Checksum:i3A23302A9DCBE5BE
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U00039 Genomic DNA. Translation: AAB18499.1.
U00096 Genomic DNA. Translation: AAC76548.1.
AP009048 Genomic DNA. Translation: BAE77771.1.
PIRiS47743.
RefSeqiNP_417980.1. NC_000913.3.
WP_001149003.1. NZ_LN832404.1.

Genome annotation databases

EnsemblBacteriaiAAC76548; AAC76548; b3523.
BAE77771; BAE77771; BAE77771.
GeneIDi948032.
KEGGiecj:JW3491.
eco:b3523.
PATRICi32122508. VBIEscCol129921_3632.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U00039 Genomic DNA. Translation: AAB18499.1.
U00096 Genomic DNA. Translation: AAC76548.1.
AP009048 Genomic DNA. Translation: BAE77771.1.
PIRiS47743.
RefSeqiNP_417980.1. NC_000913.3.
WP_001149003.1. NZ_LN832404.1.

3D structure databases

ProteinModelPortaliP37643.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi4262156. 331 interactors.
STRINGi511145.b3523.

Protein family/group databases

TCDBi2.A.1.6.10. the major facilitator superfamily (mfs).

Proteomic databases

PaxDbiP37643.
PRIDEiP37643.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAC76548; AAC76548; b3523.
BAE77771; BAE77771; BAE77771.
GeneIDi948032.
KEGGiecj:JW3491.
eco:b3523.
PATRICi32122508. VBIEscCol129921_3632.

Organism-specific databases

EchoBASEiEB2160.
EcoGeneiEG12249. yhjE.

Phylogenomic databases

eggNOGiENOG4105CSH. Bacteria.
ENOG410XP7I. LUCA.
HOGENOMiHOG000141611.
InParanoidiP37643.
OMAiSTYAQAP.
PhylomeDBiP37643.

Enzyme and pathway databases

BioCyciEcoCyc:YHJE-MONOMER.
ECOL316407:JW3491-MONOMER.

Miscellaneous databases

PROiP37643.

Family and domain databases

CDDicd06174. MFS. 1 hit.
InterProiIPR004736. Cit_H_symport.
IPR011701. MFS.
IPR020846. MFS_dom.
IPR005828. MFS_sugar_transport-like.
IPR005829. Sugar_transporter_CS.
[Graphical view]
PfamiPF07690. MFS_1. 1 hit.
PF00083. Sugar_tr. 1 hit.
[Graphical view]
SUPFAMiSSF103473. SSF103473. 1 hit.
TIGRFAMsiTIGR00883. 2A0106. 1 hit.
PROSITEiPS50850. MFS. 1 hit.
PS00216. SUGAR_TRANSPORT_1. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiYHJE_ECOLI
AccessioniPrimary (citable) accession number: P37643
Secondary accession number(s): Q2M7I5
Entry historyi
Integrated into UniProtKB/Swiss-Prot: October 1, 1994
Last sequence update: October 1, 1994
Last modified: November 30, 2016
This is version 125 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Escherichia coli
    Escherichia coli (strain K12): entries and cross-references to EcoGene
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.