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Protein

Uncharacterized HTH-type transcriptional regulator YhjC

Gene

yhjC

Organism
Escherichia coli (strain K12)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
DNA bindingi19 – 38H-T-H motifPROSITE-ProRule annotationAdd BLAST20

GO - Molecular functioni

GO - Biological processi

  • transcription, DNA-templated Source: EcoCyc
Complete GO annotation...

Keywords - Biological processi

Transcription, Transcription regulation

Keywords - Ligandi

DNA-binding

Enzyme and pathway databases

BioCyciEcoCyc:EG12247-MONOMER.
ECOL316407:JW3489-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Uncharacterized HTH-type transcriptional regulator YhjC
Gene namesi
Name:yhjC
Ordered Locus Names:b3521, JW3489
OrganismiEscherichia coli (strain K12)
Taxonomic identifieri83333 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesEnterobacteriaceaeEscherichia
Proteomesi
  • UP000000318 Componenti: Chromosome
  • UP000000625 Componenti: Chromosome

Organism-specific databases

EcoGeneiEG12247. yhjC.

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001057991 – 299Uncharacterized HTH-type transcriptional regulator YhjCAdd BLAST299

Proteomic databases

PaxDbiP37641.
PRIDEiP37641.

Interactioni

Protein-protein interaction databases

BioGridi4262157. 9 interactors.
DIPiDIP-12378N.
IntActiP37641. 2 interactors.
STRINGi511145.b3521.

Structurei

3D structure databases

ProteinModelPortaliP37641.
SMRiP37641.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini1 – 59HTH lysR-typePROSITE-ProRule annotationAdd BLAST59

Sequence similaritiesi

Contains 1 HTH lysR-type DNA-binding domain.PROSITE-ProRule annotation

Phylogenomic databases

eggNOGiENOG4105CBN. Bacteria.
ENOG410XNVB. LUCA.
HOGENOMiHOG000233519.
InParanoidiP37641.
OMAiVNFRASH.
PhylomeDBiP37641.

Family and domain databases

Gene3Di1.10.10.10. 1 hit.
InterProiIPR005119. LysR_subst-bd.
IPR000847. Tscrpt_reg_HTH_LysR.
IPR011991. WHTH_DNA-bd_dom.
[Graphical view]
PfamiPF00126. HTH_1. 1 hit.
PF03466. LysR_substrate. 1 hit.
[Graphical view]
SUPFAMiSSF46785. SSF46785. 1 hit.
PROSITEiPS50931. HTH_LYSR. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P37641-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MDKIHAMQLF IKVAELESFS RAADFFALPK GSVSRQIQAL EHQLGTQLLQ
60 70 80 90 100
RTTRRVKLTP EGMTYYQRAK DVLSNLSELD GLFQQDATSI SGKLRIDIPP
110 120 130 140 150
GIAKSLLLPR LSEFLYLHPG IELELSSHDR PVDILHDGFD CVIRTGALPE
160 170 180 190 200
DGVIARPLGK LTMVNCASPH YLTRFGYPQS PDDLTSHAIV RYTPHLGVHP
210 220 230 240 250
LGFEVASVNG VQWFKSGGML TVNSSENYLT AGLAGLGIIQ IPRIAVREAL
260 270 280 290
RAGRLIEVLP GYRAEPLSLS LVYPQRRELS RRVNLFMQWL AGVMKEYLD
Length:299
Mass (Da):33,330
Last modified:December 15, 1998 - v2
Checksum:i22D0EC5994CBC8C1
GO

Sequence cautioni

The sequence AAB18497 differs from that shown. Reason: Erroneous initiation.Curated
The sequence BAE77773 differs from that shown. Reason: Erroneous initiation.Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U00039 Genomic DNA. Translation: AAB18497.1. Different initiation.
U00096 Genomic DNA. Translation: AAC76546.2.
AP009048 Genomic DNA. Translation: BAE77773.1. Different initiation.
PIRiS47741.
RefSeqiNP_417978.2. NC_000913.3.
WP_000357790.1. NZ_LN832404.1.

Genome annotation databases

EnsemblBacteriaiAAC76546; AAC76546; b3521.
BAE77773; BAE77773; BAE77773.
GeneIDi948035.
KEGGiecj:JW3489.
eco:b3521.
PATRICi32122504. VBIEscCol129921_3630.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U00039 Genomic DNA. Translation: AAB18497.1. Different initiation.
U00096 Genomic DNA. Translation: AAC76546.2.
AP009048 Genomic DNA. Translation: BAE77773.1. Different initiation.
PIRiS47741.
RefSeqiNP_417978.2. NC_000913.3.
WP_000357790.1. NZ_LN832404.1.

3D structure databases

ProteinModelPortaliP37641.
SMRiP37641.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi4262157. 9 interactors.
DIPiDIP-12378N.
IntActiP37641. 2 interactors.
STRINGi511145.b3521.

Proteomic databases

PaxDbiP37641.
PRIDEiP37641.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAC76546; AAC76546; b3521.
BAE77773; BAE77773; BAE77773.
GeneIDi948035.
KEGGiecj:JW3489.
eco:b3521.
PATRICi32122504. VBIEscCol129921_3630.

Organism-specific databases

EchoBASEiEB2158.
EcoGeneiEG12247. yhjC.

Phylogenomic databases

eggNOGiENOG4105CBN. Bacteria.
ENOG410XNVB. LUCA.
HOGENOMiHOG000233519.
InParanoidiP37641.
OMAiVNFRASH.
PhylomeDBiP37641.

Enzyme and pathway databases

BioCyciEcoCyc:EG12247-MONOMER.
ECOL316407:JW3489-MONOMER.

Miscellaneous databases

PROiP37641.

Family and domain databases

Gene3Di1.10.10.10. 1 hit.
InterProiIPR005119. LysR_subst-bd.
IPR000847. Tscrpt_reg_HTH_LysR.
IPR011991. WHTH_DNA-bd_dom.
[Graphical view]
PfamiPF00126. HTH_1. 1 hit.
PF03466. LysR_substrate. 1 hit.
[Graphical view]
SUPFAMiSSF46785. SSF46785. 1 hit.
PROSITEiPS50931. HTH_LYSR. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiYHJC_ECOLI
AccessioniPrimary (citable) accession number: P37641
Secondary accession number(s): Q2M7I3
Entry historyi
Integrated into UniProtKB/Swiss-Prot: October 1, 1994
Last sequence update: December 15, 1998
Last modified: November 2, 2016
This is version 115 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Escherichia coli
    Escherichia coli (strain K12): entries and cross-references to EcoGene
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.