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Protein

Inner membrane protein YhiM

Gene

yhiM

Organism
Escherichia coli (strain K12)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

Enzyme and pathway databases

BioCyciEcoCyc:MONOMER0-2489.
ECOL316407:JW5944-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Inner membrane protein YhiM
Gene namesi
Name:yhiM
Ordered Locus Names:b3491, JW5944
OrganismiEscherichia coli (strain K12)
Taxonomic identifieri83333 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeEscherichia
Proteomesi
  • UP000000318 Componenti: Chromosome
  • UP000000625 Componenti: Chromosome

Organism-specific databases

EcoGeneiEG12228. yhiM.

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Topological domaini1 – 22CytoplasmicSequence analysis
Transmembranei3 – 2321HelicalSequence analysisAdd
BLAST
Topological domaini24 – 4118PeriplasmicSequence analysisAdd
BLAST
Transmembranei42 – 6221HelicalSequence analysisAdd
BLAST
Topological domaini63 – 7412CytoplasmicSequence analysisAdd
BLAST
Transmembranei75 – 9521HelicalSequence analysisAdd
BLAST
Topological domaini96 – 1049PeriplasmicSequence analysis
Transmembranei105 – 12521HelicalSequence analysisAdd
BLAST
Topological domaini126 – 15732CytoplasmicSequence analysisAdd
BLAST
Transmembranei158 – 17821HelicalSequence analysisAdd
BLAST
Topological domaini179 – 19012PeriplasmicSequence analysisAdd
BLAST
Transmembranei191 – 21121HelicalSequence analysisAdd
BLAST
Topological domaini212 – 22514CytoplasmicSequence analysisAdd
BLAST
Transmembranei226 – 24621HelicalSequence analysisAdd
BLAST
Topological domaini247 – 25711PeriplasmicSequence analysisAdd
BLAST
Transmembranei258 – 27821HelicalSequence analysisAdd
BLAST
Topological domaini279 – 29012CytoplasmicSequence analysisAdd
BLAST
Transmembranei291 – 31121HelicalSequence analysisAdd
BLAST
Topological domaini312 – 32413PeriplasmicSequence analysisAdd
BLAST
Transmembranei325 – 34521HelicalSequence analysisAdd
BLAST
Topological domaini346 – 3505CytoplasmicSequence analysis

GO - Cellular componenti

  • integral component of plasma membrane Source: EcoCyc
  • plasma membrane Source: EcoCyc
Complete GO annotation...

Keywords - Cellular componenti

Cell inner membrane, Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 350350Inner membrane protein YhiMPRO_0000169564Add
BLAST

Proteomic databases

PaxDbiP37630.

Interactioni

Protein-protein interaction databases

BioGridi4261268. 134 interactions.
STRINGi511145.b3491.

Structurei

3D structure databases

ProteinModelPortaliP37630.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiENOG4107UNS. Bacteria.
ENOG410ZE9J. LUCA.
HOGENOMiHOG000125793.
InParanoidiP37630.
OrthoDBiEOG6JMMR1.

Family and domain databases

InterProiIPR021240. DUF2776.
[Graphical view]
PfamiPF10951. DUF2776. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P37630-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MNIYIGWLFK LIPLIMGLIC IALGGFVLES SGQSEYFVAG HVLISLAAIC
60 70 80 90 100
LALFTTAFII ISQLTRGVNT FYNTLFPIIG YAGSIITMIW GWALLAGNDV
110 120 130 140 150
MADEFVAGHV IFGVGMIAAC VSTVAASSGH FLLIPKNAAG SKSDGTPVQA
160 170 180 190 200
YSSLIGNCLI AVPVLLTLLG FIWSITLLRS ADITPHYVAG HVLLGLTAIC
210 220 230 240 250
ACLIGLVATI VHQTRNTFST KEHWLWCYWV IFLGSITVLQ GIYVLVSSDA
260 270 280 290 300
SARLAPGIIL ICLGMICYSI FSKVWLLALV WRRTCSLANR IPMIPVFTCL
310 320 330 340 350
FCLFLASFLA EMAQTDMGYF IPSRVLVGLG AVCFTLFSIV SILEAGSAKK
Length:350
Mass (Da):37,657
Last modified:November 24, 2009 - v2
Checksum:i06F32A844577C549
GO

Sequence cautioni

The sequence AAB18467.1 differs from that shown. Reason: Erroneous initiation. Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U00039 Genomic DNA. Translation: AAB18467.1. Different initiation.
U00096 Genomic DNA. Translation: AAC76516.4.
AP009048 Genomic DNA. Translation: BAE77803.1.
PIRiS47711.
RefSeqiNP_417948.4. NC_000913.3.

Genome annotation databases

EnsemblBacteriaiAAC76516; AAC76516; b3491.
BAE77803; BAE77803; BAE77803.
GeneIDi947997.
KEGGiecj:JW5944.
eco:b3491.
PATRICi32122430. VBIEscCol129921_3592.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U00039 Genomic DNA. Translation: AAB18467.1. Different initiation.
U00096 Genomic DNA. Translation: AAC76516.4.
AP009048 Genomic DNA. Translation: BAE77803.1.
PIRiS47711.
RefSeqiNP_417948.4. NC_000913.3.

3D structure databases

ProteinModelPortaliP37630.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi4261268. 134 interactions.
STRINGi511145.b3491.

Proteomic databases

PaxDbiP37630.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAC76516; AAC76516; b3491.
BAE77803; BAE77803; BAE77803.
GeneIDi947997.
KEGGiecj:JW5944.
eco:b3491.
PATRICi32122430. VBIEscCol129921_3592.

Organism-specific databases

EchoBASEiEB2140.
EcoGeneiEG12228. yhiM.

Phylogenomic databases

eggNOGiENOG4107UNS. Bacteria.
ENOG410ZE9J. LUCA.
HOGENOMiHOG000125793.
InParanoidiP37630.
OrthoDBiEOG6JMMR1.

Enzyme and pathway databases

BioCyciEcoCyc:MONOMER0-2489.
ECOL316407:JW5944-MONOMER.

Miscellaneous databases

PROiP37630.

Family and domain databases

InterProiIPR021240. DUF2776.
[Graphical view]
PfamiPF10951. DUF2776. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Analysis of the Escherichia coli genome. V. DNA sequence of the region from 76.0 to 81.5 minutes."
    Sofia H.J., Burland V., Daniels D.L., Plunkett G. III, Blattner F.R.
    Nucleic Acids Res. 22:2576-2586(1994) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: K12 / MG1655 / ATCC 47076.
  2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: K12 / MG1655 / ATCC 47076.
  3. "Highly accurate genome sequences of Escherichia coli K-12 strains MG1655 and W3110."
    Hayashi K., Morooka N., Yamamoto Y., Fujita K., Isono K., Choi S., Ohtsubo E., Baba T., Wanner B.L., Mori H., Horiuchi T.
    Mol. Syst. Biol. 2:E1-E5(2006) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: K12 / W3110 / ATCC 27325 / DSM 5911.
  4. "Global topology analysis of the Escherichia coli inner membrane proteome."
    Daley D.O., Rapp M., Granseth E., Melen K., Drew D., von Heijne G.
    Science 308:1321-1323(2005) [PubMed] [Europe PMC] [Abstract]
    Cited for: TOPOLOGY [LARGE SCALE ANALYSIS].
    Strain: K12 / MG1655 / ATCC 47076.

Entry informationi

Entry nameiYHIM_ECOLI
AccessioniPrimary (citable) accession number: P37630
Secondary accession number(s): P76704, Q2M7F3
Entry historyi
Integrated into UniProtKB/Swiss-Prot: October 1, 1994
Last sequence update: November 24, 2009
Last modified: January 20, 2016
This is version 96 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Escherichia coli
    Escherichia coli (strain K12): entries and cross-references to EcoGene

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.