P37545 (YABD_BACSU) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Uncharacterized deoxyribonuclease YabD
EC=3.1.21.-

Gene names

Name:	yabD
Ordered Locus Names:	BSU00390

Organism

Bacillus subtilis

Taxonomic identifier

1423 [NCBI]

Taxonomic lineage

Bacteria › Firmicutes › Bacillales › Bacillaceae › Bacillus

Protein attributes

Sequence length	255 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Putative deoxyribonuclease By similarity.
Cofactor	Binds 2 divalent metal cations per subunit By similarity.
Sequence similarities	Belongs to the TatD DNase family.

Ontologies

Keywords
Ligand	Metal-binding
Molecular function	Hydrolase Nuclease
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Molecular function	endodeoxyribonuclease activity, producing 5'-phosphomonoesters Inferred from electronic annotation. Source: InterPro metal ion binding Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 255	255	Uncharacterized deoxyribonuclease YabD		PRO_0000202001
Sites
	Metal binding	6	1	Divalent metal cation 1 By similarity
	Metal binding	8	1	Divalent metal cation 1 By similarity
	Metal binding	92	1	Divalent metal cation 1 By similarity
	Metal binding	92	1	Divalent metal cation 2 By similarity
	Metal binding	128	1	Divalent metal cation 2 By similarity
	Metal binding	153	1	Divalent metal cation 2 By similarity
	Metal binding	203	1	Divalent metal cation 1 By similarity

Sequences

	Sequence		Length	Mass (Da)
	P37545 [UniParc]. Last modified October 1, 1994. Version 1. Checksum: ADF8EE9F5AEB0ED4	FASTA	255	29,232
	10 20 30 40 50 60 MLFDTHAHLN AEQYDTDLEE VIERAKAEKV ERIVVVGFDR PTITRAMEMI EEYDFIYAAI 70 80 90 100 110 120 GWHPVDAIDM TEEDLAWIKE LSAHEKVVAI GEMGLDYHWD KSPKDIQKEV FRNQIALAKE 130 140 150 160 170 180 VNLPIIIHNR DATEDVVTIL KEEGAEAVGG IMHCFTGSAE VARECMKMNF YLSFGGPVTF 190 200 210 220 230 240 KNAKKPKEVV KEIPNDRLLI ETDCPFLTPH PFRGKRNEPS YVKYVAEQIA ELKEMTFEEI 250 ASITTENAKR LFRIN

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Systematic sequencing of the 180 kilobase region of the Bacillus subtilis chromosome containing the replication origin." Ogasawara N., Nakai S., Yoshikawa H. DNA Res. 1:1-14(1994) [PubMed: 7584024] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]. Strain: 168.
[2]	"The complete genome sequence of the Gram-positive bacterium Bacillus subtilis." Kunst F., Ogasawara N., Moszer I., Albertini A.M., Alloni G., Azevedo V., Bertero M.G., Bessieres P., Bolotin A., Borchert S., Borriss R., Boursier L., Brans A., Braun M., Brignell S.C., Bron S., Brouillet S., Bruschi C.V. , Caldwell B., Capuano V., Carter N.M., Choi S.-K., Codani J.-J., Connerton I.F., Cummings N.J., Daniel R.A., Denizot F., Devine K.M., Duesterhoeft A., Ehrlich S.D., Emmerson P.T., Entian K.-D., Errington J., Fabret C., Ferrari E., Foulger D., Fritz C., Fujita M., Fujita Y., Fuma S., Galizzi A., Galleron N., Ghim S.-Y., Glaser P., Goffeau A., Golightly E.J., Grandi G., Guiseppi G., Guy B.J., Haga K., Haiech J., Harwood C.R., Henaut A., Hilbert H., Holsappel S., Hosono S., Hullo M.-F., Itaya M., Jones L.-M., Joris B., Karamata D., Kasahara Y., Klaerr-Blanchard M., Klein C., Kobayashi Y., Koetter P., Koningstein G., Krogh S., Kumano M., Kurita K., Lapidus A., Lardinois S., Lauber J., Lazarevic V., Lee S.-M., Levine A., Liu H., Masuda S., Mauel C., Medigue C., Medina N., Mellado R.P., Mizuno M., Moestl D., Nakai S., Noback M., Noone D., O'Reilly M., Ogawa K., Ogiwara A., Oudega B., Park S.-H., Parro V., Pohl T.M., Portetelle D., Porwollik S., Prescott A.M., Presecan E., Pujic P., Purnelle B., Rapoport G., Rey M., Reynolds S., Rieger M., Rivolta C., Rocha E., Roche B., Rose M., Sadaie Y., Sato T., Scanlan E., Schleich S., Schroeter R., Scoffone F., Sekiguchi J., Sekowska A., Seror S.J., Serror P., Shin B.-S., Soldo B., Sorokin A., Tacconi E., Takagi T., Takahashi H., Takemaru K., Takeuchi M., Tamakoshi A., Tanaka T., Terpstra P., Tognoni A., Tosato V., Uchiyama S., Vandenbol M., Vannier F., Vassarotti A., Viari A., Wambutt R., Wedler E., Wedler H., Weitzenegger T., Winters P., Wipat A., Yamamoto H., Yamane K., Yasumoto K., Yata K., Yoshida K., Yoshikawa H.-F., Zumstein E., Yoshikawa H., Danchin A. Nature 390:249-256(1997) [PubMed: 9384377] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: 168.

Cross-references

Sequence databases
EMBL GenBank DDBJ	D26185 Genomic DNA. Translation: BAA05274.1. AL009126 Genomic DNA. Translation: CAB11815.1.
PIR	S66068.
RefSeq	NP_387920.1. NC_000964.3.
3D structure databases
ProteinModelPortal	P37545.
SMR	P37545. Positions 2-252.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	EBBACT00000003039; EBBACP00000003039; EBBACG00000003033.
GeneID	936949.
GenomeReviews	Gene locus BSU00390 in contig AL009126_GR.
KEGG	bsu:BSU00390.
NMPDR	fig|224308.1.peg.39.
PATRIC	18971549. VBIBacSub10457_0040.
Organism-specific databases
GenoList	BSU00390.
Phylogenomic databases
GeneTree	EBGT00050000002835.
HOGENOM	HBG629833.
OMA	LPLVIHT.
PhylomeDB	P37545.
ProtClustDB	CLSK872601.
Enzyme and pathway databases
BioCyc	BSUB:BSU00390-MONOMER.
Family and domain databases
InterPro	IPR012278. DNase_TatD. IPR018228. DNase_TatD-rel_CS. IPR015991. DNase_TatD_bac-type. IPR001130. TatD_superfamily. [Graphical view]
KO	K03424.
PANTHER	PTHR10060. TatD_DNase. 1 hit.
Pfam	PF01026. TatD_DNase. 1 hit. [Graphical view]
PIRSF	PIRSF005902. DNase_TatD. 1 hit.
TIGRFAMs	TIGR00010. TIGR00010. 1 hit.
PROSITE	PS01137. TATD_1. 1 hit. PS01090. TATD_2. 1 hit. PS01091. TATD_3. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

YABD_BACSU

Accession

Primary (citable) accession number: P37545

Entry history

Integrated into UniProtKB/Swiss-Prot:	October 1, 1994
Last sequence update:	October 1, 1994
Last modified:	January 25, 2012
This is version 79 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program