Reviewed, UniProtKB/Swiss-Prot P37531 (YAAH_BACSU)

Names and origin

Protein names

Recommended name:
    Spore germination protein yaaH

Gene names

Name:	yaaH
Ordered Locus Names:	BSU00160

Organism

Bacillus subtilis [Complete proteome] [HAMAP]

Taxonomic identifier

1423 [NCBI]

Taxonomic lineage

Bacteria › Firmicutes › Bacillales › Bacillaceae › Bacillus

Protein attributes

Sequence length	427 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Evidence at transcript level.

General annotation (Comments)

Function	May be required for the L-alanine-stimulated germination pathway. Ref.3
Subcellular location	Spore wall Probable. Note: Probably localized either on the surface of the outer spore membrane and/or in the inner spore coat.
Developmental stage	Expressed in the mother cell compartment from T2 of sporulation.
Domain	LysM repeats are thought to be involved in peptidoglycan binding.
Miscellaneous	Transcribed by the sigE RNA polymerase. Inactivation of the yaaH gene does not impair vegetative growth nor prevent the development of resistance to heat, chloroform and lysozyme.
Sequence similarities	Contains 2 LysM repeats.

Ontologies

Keywords
Biological process	Germination
Domain	Repeat
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	cell wall macromolecule catabolic process Inferred from electronic annotation. Source: InterPro chitin catabolic process Inferred from electronic annotation. Source: InterPro
Cellular component	spore wall Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	cation binding Inferred from electronic annotation. Source: InterPro chitinase activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 427	427	Spore germination protein yaaH		PRO_0000049432
Regions
	Repeat	1 – 43	43	LysM 1
	Repeat	49 – 92	44	LysM 2

Sequences

	Sequence		Length	Mass (Da)
	P37531-1 [UniParc]. Last modified October 1, 1994. Version 1. Checksum: 77FEF6AB327379A3	FASTA	427	48,637
	10 20 30 40 50 60 MVKQGDTLSA IASQYRTTTN DITETNEIPN PDSLVVGQTI VIPIAGQFYD VKRGDTLTSI 70 80 90 100 110 120 ARQFNTTAAE LARVNRIQLN TVLQIGFRLY IPPAPKRDIE SNAYLEPRGN QVSENLQQAA 130 140 150 160 170 180 REASPYLTYL GAFSFQAQRN GTLVAPPLTN LRSITESQNT TLMMIITNLE NQAFSDELGR 190 200 210 220 230 240 ILLNDETVKR RLLNEIVENA RRYGFRDIHF DFEYLRPQDR EAYNQFLREA RDLFHREGLE 250 260 270 280 290 300 ISTALAPKTS ATQQGRWYEA HDYRAHGEIV DFVVLMTYEW GYSGGPPQAV SPIGPVRDVI 310 320 330 340 350 360 EYALTEMPAN KIVMGQNLYG YDWTLPYTAG GTPARAVSPQ QAIVIADQNN ASIQYDQTAQ 370 380 390 400 410 420 APFFRYTDAE NRRHEVWFED ARSIQAKFNL IKELNLRGIS YWKLGLSFPQ NWLLLSDQFN VVKKTFR

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Systematic sequencing of the 180 kilobase region of the Bacillus subtilis chromosome containing the replication origin." Ogasawara N., Nakai S., Yoshikawa H. DNA Res. 1:1-14(1994) [PubMed: 7584024] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]. Strain: 168.
[2]	"The complete genome sequence of the Gram-positive bacterium Bacillus subtilis." Kunst F., Ogasawara N., Moszer I., Albertini A.M., Alloni G., Azevedo V., Bertero M.G., Bessieres P., Bolotin A., Borchert S., Borriss R., Boursier L., Brans A., Braun M., Brignell S.C., Bron S., Brouillet S., Bruschi C.V. , Caldwell B., Capuano V., Carter N.M., Choi S.-K., Codani J.-J., Connerton I.F., Cummings N.J., Daniel R.A., Denizot F., Devine K.M., Duesterhoeft A., Ehrlich S.D., Emmerson P.T., Entian K.-D., Errington J., Fabret C., Ferrari E., Foulger D., Fritz C., Fujita M., Fujita Y., Fuma S., Galizzi A., Galleron N., Ghim S.-Y., Glaser P., Goffeau A., Golightly E.J., Grandi G., Guiseppi G., Guy B.J., Haga K., Haiech J., Harwood C.R., Henaut A., Hilbert H., Holsappel S., Hosono S., Hullo M.-F., Itaya M., Jones L.-M., Joris B., Karamata D., Kasahara Y., Klaerr-Blanchard M., Klein C., Kobayashi Y., Koetter P., Koningstein G., Krogh S., Kumano M., Kurita K., Lapidus A., Lardinois S., Lauber J., Lazarevic V., Lee S.-M., Levine A., Liu H., Masuda S., Mauel C., Medigue C., Medina N., Mellado R.P., Mizuno M., Moestl D., Nakai S., Noback M., Noone D., O'Reilly M., Ogawa K., Ogiwara A., Oudega B., Park S.-H., Parro V., Pohl T.M., Portetelle D., Porwollik S., Prescott A.M., Presecan E., Pujic P., Purnelle B., Rapoport G., Rey M., Reynolds S., Rieger M., Rivolta C., Rocha E., Roche B., Rose M., Sadaie Y., Sato T., Scanlan E., Schleich S., Schroeter R., Scoffone F., Sekiguchi J., Sekowska A., Seror S.J., Serror P., Shin B.-S., Soldo B., Sorokin A., Tacconi E., Takagi T., Takahashi H., Takemaru K., Takeuchi M., Tamakoshi A., Tanaka T., Terpstra P., Tognoni A., Tosato V., Uchiyama S., Vandenbol M., Vannier F., Vassarotti A., Viari A., Wambutt R., Wedler E., Wedler H., Weitzenegger T., Winters P., Wipat A., Yamamoto H., Yamane K., Yasumoto K., Yata K., Yoshida K., Yoshikawa H.-F., Zumstein E., Yoshikawa H., Danchin A. Nature 390:249-256(1997) [PubMed: 9384377] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: 168.
[3]	"The Bacillus subtilis yaaH gene is transcribed by SigE RNA polymerase during sporulation, and its product is involved in germination of spores." Kodama T., Takamatsu H., Asai K., Kobayashi K., Ogasawara N., Watabe K. J. Bacteriol. 181:4584-4591(1999) [PubMed: 10419957] [Abstract] Cited for: FUNCTION, EXPRESSION. Strain: 168.

Cross-references

Sequence databases
EMBLGenBankDDBJ	D26185 Genomic DNA. Translation: BAA05252.1. AL009126 Genomic DNA. Translation: CAB11792.1.
PIR	S66046.
RefSeq	NP_387897.1.
3D structure databases
ModBase	Search...
Genome annotation databases
GeneID	937029.
GenomeReviews	Gene locus BSU00160 in contig AL009126_GR.
KEGG	bsu:BSU00160.
NMPDR	fig|224308.1.peg.16.
Organism-specific databases
SubtiList	BG10080. yaaH. [Micado]
CMR	Search...
Phylogenomic databases
HOGENOM	HBG337948.
OMA	MGQNLYG.
Family and domain databases
InterPro	IPR011583. Chitinase_II. IPR001223. Glyco_hydro18cat. IPR017853. Glyco_hydro_catalytic_core. IPR013781. Glyco_hydro_sg_catalytic. IPR018392. Peptidoglycan-bd_lysin. IPR002482. Peptidoglycan-bd_Lysin_sg. [Graphical view]
Gene3D	G3DSA:3.20.20.80. Glyco_hydro_cat. 1 hit.
Pfam	PF00704. Glyco_hydro_18. 1 hit. PF01476. LysM. 2 hits. [Graphical view]
SMART	SM00636. Glyco_18. 1 hit. SM00257. LysM. 2 hits. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

YAAH_BACSU

Accession

Primary (citable) accession number: P37531

Entry history

Integrated into UniProtKB/Swiss-Prot:	October 1, 1994
Last sequence update:	October 1, 1994
Last modified:	December 15, 2009
This is version 69 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)