Reviewed, UniProtKB/Swiss-Prot P37522 (SOJ_BACSU)

Names and origin

Protein names

Recommended name:
    Sporulation initiation inhibitor protein soj

Gene names

Name:	soj
Ordered Locus Names:	BSU40970

Organism

Bacillus subtilis [Complete proteome] [HAMAP]

Taxonomic identifier

1423 [NCBI]

Taxonomic lineage

Bacteria › Firmicutes › Bacillales › Bacillaceae › Bacillus

Protein attributes

Sequence length	253 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Evidence at protein level.

General annotation (Comments)

Function	Inhibits the initiation of sporulation, spo0J antagonizes this inhibition. Soj ultimately inhibits the activation (phosphorylation) of spo0A. It is not required for chromosome partitioning. Ref.4
Sequence similarities	Belongs to the parA family.

Ontologies

Keywords
Biological process	Sporulation
Ligand	ATP-binding Nucleotide-binding
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	cobalamin biosynthetic process Inferred from electronic annotation. Source: InterPro oxidation reduction Inferred from electronic annotation. Source: InterPro sporulation resulting in formation of a cellular spore Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	ATP binding Inferred from electronic annotation. Source: UniProtKB-KW cobyrinic acid a,c-diamide synthase activity Inferred from electronic annotation. Source: InterPro oxidoreductase activity Inferred from electronic annotation. Source: InterPro protein binding Inferred from physical interaction. Source: IntAct
Complete GO annotation...

Binary interactions

With	Entry	#Exp.	IntAct	Notes
dnaA	P05648	1	EBI-2014674,EBI-2014722

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 253	253	Sporulation initiation inhibitor protein soj		PRO_0000201981
Regions
	Nucleotide binding	10 – 17	8	ATP Potential

Sequences

	Sequence		Length	Mass (Da)
	P37522-1 [UniParc]. Last modified October 1, 1994. Version 1. Checksum: 6BEBB5590EB92F78	FASTA	253	27,543
	10 20 30 40 50 60 MGKIIAITNQ KGGVGKTTTS VNLGACLAYI GKRVLLVDID PQGNATSGLG IEKADVEQCV 70 80 90 100 110 120 YDILVDDADV IDIIKATTVE NLDVIPATIQ LAGAEIELVP TISREVRLKR ALEAVKQNYD 130 140 150 160 170 180 YIIIDCPPSL GLLTINALTA SDSVVIPVQC EYYALEGLSQ LLNTVRLVQK HLNTDLMIEG 190 200 210 220 230 240 VLLTMLDART NLGIQVIEEV KKYFRDKVYK TVIPRNVRLS EAPSHGKPII LYDPRSRGAE 250 VYLDLAKEVA ANG

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Genes and their organization in the replication origin region of the bacterial chromosome." Ogasawara N., Yoshikawa H. Mol. Microbiol. 6:629-634(1992) [PubMed: 1552862] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]. Strain: 168 / CRK2000.
[2]	"Systematic sequencing of the 180 kilobase region of the Bacillus subtilis chromosome containing the replication origin." Ogasawara N., Nakai S., Yoshikawa H. DNA Res. 1:1-14(1994) [PubMed: 7584024] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]. Strain: 168.
[3]	"The complete genome sequence of the Gram-positive bacterium Bacillus subtilis." Kunst F., Ogasawara N., Moszer I., Albertini A.M., Alloni G., Azevedo V., Bertero M.G., Bessieres P., Bolotin A., Borchert S., Borriss R., Boursier L., Brans A., Braun M., Brignell S.C., Bron S., Brouillet S., Bruschi C.V. , Caldwell B., Capuano V., Carter N.M., Choi S.-K., Codani J.-J., Connerton I.F., Cummings N.J., Daniel R.A., Denizot F., Devine K.M., Duesterhoeft A., Ehrlich S.D., Emmerson P.T., Entian K.-D., Errington J., Fabret C., Ferrari E., Foulger D., Fritz C., Fujita M., Fujita Y., Fuma S., Galizzi A., Galleron N., Ghim S.-Y., Glaser P., Goffeau A., Golightly E.J., Grandi G., Guiseppi G., Guy B.J., Haga K., Haiech J., Harwood C.R., Henaut A., Hilbert H., Holsappel S., Hosono S., Hullo M.-F., Itaya M., Jones L.-M., Joris B., Karamata D., Kasahara Y., Klaerr-Blanchard M., Klein C., Kobayashi Y., Koetter P., Koningstein G., Krogh S., Kumano M., Kurita K., Lapidus A., Lardinois S., Lauber J., Lazarevic V., Lee S.-M., Levine A., Liu H., Masuda S., Mauel C., Medigue C., Medina N., Mellado R.P., Mizuno M., Moestl D., Nakai S., Noback M., Noone D., O'Reilly M., Ogawa K., Ogiwara A., Oudega B., Park S.-H., Parro V., Pohl T.M., Portetelle D., Porwollik S., Prescott A.M., Presecan E., Pujic P., Purnelle B., Rapoport G., Rey M., Reynolds S., Rieger M., Rivolta C., Rocha E., Roche B., Rose M., Sadaie Y., Sato T., Scanlan E., Schleich S., Schroeter R., Scoffone F., Sekiguchi J., Sekowska A., Seror S.J., Serror P., Shin B.-S., Soldo B., Sorokin A., Tacconi E., Takagi T., Takahashi H., Takemaru K., Takeuchi M., Tamakoshi A., Tanaka T., Terpstra P., Tognoni A., Tosato V., Uchiyama S., Vandenbol M., Vannier F., Vassarotti A., Viari A., Wambutt R., Wedler E., Wedler H., Weitzenegger T., Winters P., Wipat A., Yamamoto H., Yamane K., Yasumoto K., Yata K., Yoshida K., Yoshikawa H.-F., Zumstein E., Yoshikawa H., Danchin A. Nature 390:249-256(1997) [PubMed: 9384377] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: 168.
[4]	"spo0J is required for normal chromosome segregation as well as the initiation of sporulation in Bacillus subtilis." Ireton K., Gunther N.W. IV, Grossman A.D. J. Bacteriol. 176:5320-5329(1994) [PubMed: 8071208] [Abstract] Cited for: FUNCTION.

Cross-references

Sequence databases
EMBLGenBankDDBJ	X62539 Genomic DNA. Translation: CAA44408.1. D26185 Genomic DNA. Translation: BAA05227.1. AL009126 Genomic DNA. Translation: CAB16134.1.
PIR	I40444.
RefSeq	NP_391977.1.
3D structure databases
ModBase	Search...
Protein-protein interaction databases
IntAct	P37522. 3 interactions.
Genome annotation databases
GeneID	937928.
GenomeReviews	Gene locus BSU40970 in contig AL009126_GR.
KEGG	bsu:BSU40970.
NMPDR	fig|224308.1.peg.4103.
Organism-specific databases
SubtiList	BG10055. soj. [Micado]
CMR	Search...
Phylogenomic databases
HOGENOM	P37522.
OMA	NLVGMEV
Family and domain databases
InterPro	IPR002586. CbiA_P_synth. IPR000392. Nitogenase_NifH/Reductase_ChlL. [Graphical view]
Pfam	PF01656. CbiA. 1 hit. [Graphical view]
PRINTS	PR00091. NITROGNASEII.
ProtoNet	Search...

Entry information

Entry name

SOJ_BACSU

Accession

Primary (citable) accession number: P37522

Entry history

Integrated into UniProtKB/Swiss-Prot:	October 1, 1994
Last sequence update:	October 1, 1994
Last modified:	November 24, 2009
This is version 69 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)