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Protein

Uncharacterized protein YcaI

Gene

ycaI

Organism
Escherichia coli (strain K12)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein predictedi

Functioni

GO - Biological processi

Complete GO annotation...

Enzyme and pathway databases

BioCyciEcoCyc:EG12375-MONOMER.
ECOL316407:JW5120-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Uncharacterized protein YcaI
Gene namesi
Name:ycaI
Ordered Locus Names:b0913, JW5120
OrganismiEscherichia coli (strain K12)
Taxonomic identifieri83333 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesEnterobacteriaceaeEscherichia
Proteomesi
  • UP000000318 Componenti: Chromosome
  • UP000000625 Componenti: Chromosome

Organism-specific databases

EcoGeneiEG12375. ycaI.

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei3 – 23HelicalSequence analysisAdd BLAST21
Transmembranei24 – 44HelicalSequence analysisAdd BLAST21
Transmembranei50 – 70HelicalSequence analysisAdd BLAST21
Transmembranei223 – 243HelicalSequence analysisAdd BLAST21
Transmembranei254 – 274HelicalSequence analysisAdd BLAST21
Transmembranei320 – 340HelicalSequence analysisAdd BLAST21
Transmembranei370 – 390HelicalSequence analysisAdd BLAST21
Transmembranei392 – 412HelicalSequence analysisAdd BLAST21
Transmembranei446 – 466HelicalSequence analysisAdd BLAST21
Transmembranei471 – 491HelicalSequence analysisAdd BLAST21

GO - Cellular componenti

  • integral component of membrane Source: UniProtKB-KW
  • plasma membrane Source: EcoCyc
Complete GO annotation...

Keywords - Cellular componenti

Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001687541 – 754Uncharacterized protein YcaIAdd BLAST754

Proteomic databases

PaxDbiP37443.
PRIDEiP37443.

Interactioni

Protein-protein interaction databases

BioGridi4261065. 121 interactors.
STRINGi511145.b0913.

Structurei

3D structure databases

ProteinModelPortaliP37443.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

To B.subtilis ComEC, N.gonorrhoeae ComA, and H.influenzae Rec2.Curated

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiENOG4108EQH. Bacteria.
COG0658. LUCA.
COG2333. LUCA.
HOGENOMiHOG000262044.
InParanoidiP37443.
KOiK02238.
OMAiVHLMVIS.
PhylomeDBiP37443.

Family and domain databases

Gene3Di3.60.15.10. 1 hit.
InterProiIPR004477. ComEC_N.
IPR004797. Competence_ComEC/Rec2.
IPR001279. Metallo-B-lactamas.
[Graphical view]
PfamiPF03772. Competence. 1 hit.
PF00753. Lactamase_B. 1 hit.
[Graphical view]
SMARTiSM00849. Lactamase_B. 1 hit.
[Graphical view]
SUPFAMiSSF56281. SSF56281. 1 hit.
TIGRFAMsiTIGR00360. ComEC_N-term. 1 hit.
TIGR00361. ComEC_Rec2. 1 hit.

Sequencei

Sequence statusi: Complete.

P37443-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKITTVGVCI ISGIFPLLIL PQLPGTLTLA FLTLFACVLA FIPVKTVRYI
60 70 80 90 100
ALTLLFFVWG ILSAKQILWA GETLTGATQD AIVEITATDG MTTHYGQITH
110 120 130 140 150
LQGRRIFPAS GLVMYGEYLP QAVCAGQQWS MKLKVRAVHG QLNDGGFDSQ
160 170 180 190 200
RYAIAQHQPL TGRFLQASVI EPNCSLRAQY LASLQTTLQP YPWNAVILGL
210 220 230 240 250
GMGERLSVPK EIKNIMRDTG TAHLMAISGL HIAFAALLAA GLIRSGQIFL
260 270 280 290 300
PGRWIHWQIP LIGGICCAAF YAWLTGMQPP ALRTMVALAT WGMLKLSGRQ
310 320 330 340 350
WSGWDVWICC LAAILLMDPV AILSQSLWLS AAAVAALIFW YQWFPCPEWQ
360 370 380 390 400
LPPVLRAVVS LIHLQLGITL LLMPVQIVIF HGISLTSFIA NLLAIPLVTF
410 420 430 440 450
ITVPLILAAM VVHLSGPLIL EQGLWFLADR SLALLFWGLK SLPEGWINIA
460 470 480 490 500
ECWQWLSFSP WFLLVVWRLN AWRTLPAMCV AGGLLMCWPL WQKPRPDEWQ
510 520 530 540 550
LYMLDVGQGL AMVIARNGKA ILYDTGLAWP EGDSGQQLII PWLHWHNLEP
560 570 580 590 600
EGVILSHEHL DHRGGLDSIL HIWPMLWIRS PLNWEHHQPC VRGEAWQWQG
610 620 630 640 650
LRFSAHWPLQ GSNDKGNNHS CVVKVDDGTN SILLTGDIEA PAEQKMLSRY
660 670 680 690 700
WQQVQATLLQ VPHHGSNTSS SLPLIQRVNG KVALASASRY NAWRLPSNKV
710 720 730 740 750
KHRYQLQGYQ WIDTPHQGQT TVNFSAQGWR ISSLREQILP RWYHQWFGVP

VDNG
Length:754
Mass (Da):84,474
Last modified:April 27, 2001 - v3
Checksum:iC3423D13889AF170
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti581 – 595PLNWE…VRGEA → SVKLGTSSALCAWRT in Z11796 (PubMed:8094880).CuratedAdd BLAST15

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U00096 Genomic DNA. Translation: AAC73999.2.
AP009048 Genomic DNA. Translation: BAA35657.2.
Z11796 Genomic DNA. No translation available.
PIRiH64830.
RefSeqiNP_415433.4. NC_000913.3.
WP_000705764.1. NZ_LN832404.1.

Genome annotation databases

EnsemblBacteriaiAAC73999; AAC73999; b0913.
BAA35657; BAA35657; BAA35657.
GeneIDi945531.
KEGGiecj:JW5120.
eco:b0913.
PATRICi32117039. VBIEscCol129921_0944.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U00096 Genomic DNA. Translation: AAC73999.2.
AP009048 Genomic DNA. Translation: BAA35657.2.
Z11796 Genomic DNA. No translation available.
PIRiH64830.
RefSeqiNP_415433.4. NC_000913.3.
WP_000705764.1. NZ_LN832404.1.

3D structure databases

ProteinModelPortaliP37443.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi4261065. 121 interactors.
STRINGi511145.b0913.

Proteomic databases

PaxDbiP37443.
PRIDEiP37443.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAC73999; AAC73999; b0913.
BAA35657; BAA35657; BAA35657.
GeneIDi945531.
KEGGiecj:JW5120.
eco:b0913.
PATRICi32117039. VBIEscCol129921_0944.

Organism-specific databases

EchoBASEiEB2278.
EcoGeneiEG12375. ycaI.

Phylogenomic databases

eggNOGiENOG4108EQH. Bacteria.
COG0658. LUCA.
COG2333. LUCA.
HOGENOMiHOG000262044.
InParanoidiP37443.
KOiK02238.
OMAiVHLMVIS.
PhylomeDBiP37443.

Enzyme and pathway databases

BioCyciEcoCyc:EG12375-MONOMER.
ECOL316407:JW5120-MONOMER.

Miscellaneous databases

PROiP37443.

Family and domain databases

Gene3Di3.60.15.10. 1 hit.
InterProiIPR004477. ComEC_N.
IPR004797. Competence_ComEC/Rec2.
IPR001279. Metallo-B-lactamas.
[Graphical view]
PfamiPF03772. Competence. 1 hit.
PF00753. Lactamase_B. 1 hit.
[Graphical view]
SMARTiSM00849. Lactamase_B. 1 hit.
[Graphical view]
SUPFAMiSSF56281. SSF56281. 1 hit.
TIGRFAMsiTIGR00360. ComEC_N-term. 1 hit.
TIGR00361. ComEC_Rec2. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiYCAI_ECOLI
AccessioniPrimary (citable) accession number: P37443
Secondary accession number(s): P75841
Entry historyi
Integrated into UniProtKB/Swiss-Prot: October 1, 1994
Last sequence update: April 27, 2001
Last modified: November 2, 2016
This is version 128 of the entry and version 3 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Escherichia coli
    Escherichia coli (strain K12): entries and cross-references to EcoGene

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.