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Protein

Oxidoreductase UcpA

Gene

ucpA

Organism
Escherichia coli (strain K12)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Binding sitei141SubstrateBy similarity1
Active sitei155Proton acceptorBy similarity1

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi10 – 32NAD or NADPBy similarityAdd BLAST23

GO - Molecular functioni

Complete GO annotation...

Keywords - Molecular functioni

Oxidoreductase

Enzyme and pathway databases

BioCyciEcoCyc:EG12133-MONOMER.
ECOL316407:JW5394-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Oxidoreductase UcpA (EC:1.-.-.-)
Gene namesi
Name:ucpA
Synonyms:yfeF
Ordered Locus Names:b2426, JW5394
OrganismiEscherichia coli (strain K12)
Taxonomic identifieri83333 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesEnterobacteriaceaeEscherichia
Proteomesi
  • UP000000318 Componenti: Chromosome
  • UP000000625 Componenti: Chromosome

Organism-specific databases

EcoGeneiEG12133. ucpA.

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000548011 – 263Oxidoreductase UcpAAdd BLAST263

Proteomic databases

EPDiP37440.
PaxDbiP37440.
PRIDEiP37440.

Interactioni

Protein-protein interaction databases

BioGridi4260683. 6 interactors.
DIPiDIP-11073N.
IntActiP37440. 3 interactors.
MINTiMINT-1256783.
STRINGi511145.b2426.

Structurei

3D structure databases

ProteinModelPortaliP37440.
SMRiP37440.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

eggNOGiENOG4105I7Z. Bacteria.
ENOG410XSIT. LUCA.
InParanoidiP37440.
OMAiILYFQRE.
PhylomeDBiP37440.

Family and domain databases

Gene3Di3.40.50.720. 1 hit.
InterProiIPR016040. NAD(P)-bd_dom.
IPR002347. SDR_fam.
[Graphical view]
PRINTSiPR00081. GDHRDH.
PR00080. SDRFAMILY.
SUPFAMiSSF51735. SSF51735. 1 hit.

Sequencei

Sequence statusi: Complete.

P37440-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MGKLTGKTAL ITGALQGIGE GIARTFARHG ANLILLDISP EIEKLADELC
60 70 80 90 100
GRGHRCTAVV ADVRDPASVA AAIKRAKEKE GRIDILVNNA GVCRLGSFLD
110 120 130 140 150
MSDDDRDFHI DINIKGVWNV TKAVLPEMIA RKDGRIVMMS SVTGDMVADP
160 170 180 190 200
GETAYALTKA AIVGLTKSLA VEYAQSGIRV NAICPGYVRT PMAESIARQS
210 220 230 240 250
NPEDPESVLT EMAKAIPMRR LADPLEVGEL AAFLASDESS YLTGTQNVID
260
GGSTLPETVS VGI
Length:263
Mass (Da):27,850
Last modified:July 11, 2001 - v3
Checksum:i2E201713357FDF41
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti153T → Q in CAA68181 (PubMed:9241368).Curated1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X99908 Genomic DNA. Translation: CAA68181.1.
U00096 Genomic DNA. Translation: AAC75479.2.
AP009048 Genomic DNA. Translation: BAA16309.2.
M32101 Genomic DNA. No translation available.
PIRiA65017.
RefSeqiNP_416921.4. NC_000913.3.
WP_000517431.1. NZ_LN832404.1.

Genome annotation databases

EnsemblBacteriaiAAC75479; AAC75479; b2426.
BAA16309; BAA16309; BAA16309.
GeneIDi946898.
KEGGiecj:JW5394.
eco:b2426.
PATRICi32120237. VBIEscCol129921_2521.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X99908 Genomic DNA. Translation: CAA68181.1.
U00096 Genomic DNA. Translation: AAC75479.2.
AP009048 Genomic DNA. Translation: BAA16309.2.
M32101 Genomic DNA. No translation available.
PIRiA65017.
RefSeqiNP_416921.4. NC_000913.3.
WP_000517431.1. NZ_LN832404.1.

3D structure databases

ProteinModelPortaliP37440.
SMRiP37440.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi4260683. 6 interactors.
DIPiDIP-11073N.
IntActiP37440. 3 interactors.
MINTiMINT-1256783.
STRINGi511145.b2426.

Proteomic databases

EPDiP37440.
PaxDbiP37440.
PRIDEiP37440.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAC75479; AAC75479; b2426.
BAA16309; BAA16309; BAA16309.
GeneIDi946898.
KEGGiecj:JW5394.
eco:b2426.
PATRICi32120237. VBIEscCol129921_2521.

Organism-specific databases

EchoBASEiEB2054.
EcoGeneiEG12133. ucpA.

Phylogenomic databases

eggNOGiENOG4105I7Z. Bacteria.
ENOG410XSIT. LUCA.
InParanoidiP37440.
OMAiILYFQRE.
PhylomeDBiP37440.

Enzyme and pathway databases

BioCyciEcoCyc:EG12133-MONOMER.
ECOL316407:JW5394-MONOMER.

Miscellaneous databases

PROiP37440.

Family and domain databases

Gene3Di3.40.50.720. 1 hit.
InterProiIPR016040. NAD(P)-bd_dom.
IPR002347. SDR_fam.
[Graphical view]
PRINTSiPR00081. GDHRDH.
PR00080. SDRFAMILY.
SUPFAMiSSF51735. SSF51735. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiUCPA_ECOLI
AccessioniPrimary (citable) accession number: P37440
Secondary accession number(s): P76963, P77140, P77442
Entry historyi
Integrated into UniProtKB/Swiss-Prot: October 1, 1994
Last sequence update: July 11, 2001
Last modified: November 2, 2016
This is version 131 of the entry and version 3 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Escherichia coli
    Escherichia coli (strain K12): entries and cross-references to EcoGene
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.