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Protein

Xylose import ATP-binding protein XylG

Gene

xylG

Organism
Escherichia coli (strain K12)
Status
Reviewed-Annotation score: Annotation score: 4 out of 5-Experimental evidence at protein leveli

Functioni

Part of the ABC transporter complex XylFGH involved in xylose import. Responsible for energy coupling to the transport system (Probable). The XylFGH system can also transport ribose in absence of xylose.UniRule annotationCurated1 Publication

Catalytic activityi

ATP + H2O + monosaccharide(Out) = ADP + phosphate + monosaccharide(In).UniRule annotation

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi37 – 44ATPUniRule annotation8

GO - Molecular functioni

  • ATP binding Source: EcoCyc
  • D-xylose-importing ATPase activity Source: InterPro
  • D-xylose transmembrane transporter activity Source: EcoCyc

GO - Biological processi

  • D-xylose metabolic process Source: EcoCyc
  • D-xylose transport Source: EcoCyc

Keywordsi

Molecular functionHydrolase
Biological processSugar transport, Transport
LigandATP-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciEcoCyc:XYLG-MONOMER.
MetaCyc:XYLG-MONOMER.

Protein family/group databases

TCDBi3.A.1.2.4. the atp-binding cassette (abc) superfamily.

Names & Taxonomyi

Protein namesi
Recommended name:
Xylose import ATP-binding protein XylGUniRule annotation (EC:3.6.3.17UniRule annotation)
Gene namesi
Name:xylGUniRule annotation
Ordered Locus Names:b3567, JW3539
OrganismiEscherichia coli (strain K12)
Taxonomic identifieri83333 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesEnterobacteriaceaeEscherichia
Proteomesi
  • UP000000318 Componenti: Chromosome
  • UP000000625 Componenti: Chromosome

Organism-specific databases

EcoGeneiEG12275. xylG.

Subcellular locationi

  • Cell inner membrane UniRule annotation; Peripheral membrane protein UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

Cell inner membrane, Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000931241 – 513Xylose import ATP-binding protein XylGAdd BLAST513

Proteomic databases

PaxDbiP37388.
PRIDEiP37388.

Interactioni

Subunit structurei

The complex is composed of two ATP-binding proteins (XylG), two transmembrane proteins (XylH) and a solute-binding protein (XylF).UniRule annotation

Protein-protein interaction databases

BioGridi4262542. 7 interactors.
IntActiP37388. 7 interactors.
STRINGi316385.ECDH10B_3748.

Structurei

3D structure databases

ProteinModelPortaliP37388.
SMRiP37388.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini5 – 242ABC transporter 1UniRule annotationAdd BLAST238
Domaini259 – 505ABC transporter 2UniRule annotationAdd BLAST247

Sequence similaritiesi

Belongs to the ABC transporter superfamily. Xylose importer (TC 3.A.1.2.4) family. [View classification]UniRule annotation

Keywords - Domaini

Repeat

Phylogenomic databases

eggNOGiENOG4105C2J. Bacteria.
COG1129. LUCA.
InParanoidiP37388.
KOiK10545.
PhylomeDBiP37388.

Family and domain databases

InterProiView protein in InterPro
IPR003593. AAA+_ATPase.
IPR003439. ABC_transporter-like.
IPR017871. ABC_transporter_CS.
IPR013455. ABC_transptr_xylose_ATP-bd.
IPR027417. P-loop_NTPase.
PfamiView protein in Pfam
PF00005. ABC_tran. 2 hits.
SMARTiView protein in SMART
SM00382. AAA. 2 hits.
SUPFAMiSSF52540. SSF52540. 2 hits.
TIGRFAMsiTIGR02633. xylG. 1 hit.
PROSITEiView protein in PROSITE
PS00211. ABC_TRANSPORTER_1. 1 hit.
PS50893. ABC_TRANSPORTER_2. 2 hits.
PS51280. XYLG. 1 hit.

Sequencei

Sequence statusi: Complete.

P37388-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MPYLLEMKNI TKTFGSVKAI DNVCLRLNAG EIVSLCGENG SGKSTLMKVL
60 70 80 90 100
CGIYPHGSYE GEIIFAGEEI QASHIRDTER KGIAIIHQEL ALVKELTVLE
110 120 130 140 150
NIFLGNEITH NGIMDYDLMT LRCQKLLAQV SLSISPDTRV GDLGLGQQQL
160 170 180 190 200
VEIAKALNKQ VRLLILDEPT ASLTEQETSI LLDIIRDLQQ HGIACIYISH
210 220 230 240 250
KLNEVKAISD TICVIRDGQH IGTRDAAGMS EDDIITMMVG RELTALYPNE
260 270 280 290 300
PHTTGDEILR IEHLTAWHPV NRHIKRVNDV SFSLKRGEIL GIAGLVGAGR
310 320 330 340 350
TETIQCLFGV WPGQWEGKIY IDGKQVDIRN CQQAIAQGIA MVPEDRKRDG
360 370 380 390 400
IVPVMAVGKN ITLAALNKFT GGISQLDDAA EQKCILESIQ QLKVKTSSPD
410 420 430 440 450
LAIGRLSGGN QQKAILARCL LLNPRILILD EPTRGIDIGA KYEIYKLINQ
460 470 480 490 500
LVQQGIAVIV ISSELPEVLG LSDRVLVMHE GKLKANLINH NLTQEQVMEA
510
ALRSEHHVEK QSV
Length:513
Mass (Da):56,470
Last modified:October 1, 1994 - v1
Checksum:iFAD2C65D178D50DF
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U00039 Genomic DNA. Translation: AAB18544.1.
U00096 Genomic DNA. Translation: AAC76591.1.
AP009048 Genomic DNA. Translation: BAE77726.1.
PIRiS47788.
RefSeqiNP_418024.1. NC_000913.3.
WP_001146473.1. NZ_LN832404.1.

Genome annotation databases

EnsemblBacteriaiAAC76591; AAC76591; b3567.
BAE77726; BAE77726; BAE77726.
GeneIDi948127.
KEGGiecj:JW3539.
eco:b3567.
PATRICifig|1411691.4.peg.3145.

Similar proteinsi

Entry informationi

Entry nameiXYLG_ECOLI
AccessioniPrimary (citable) accession number: P37388
Secondary accession number(s): Q2M7N0
Entry historyiIntegrated into UniProtKB/Swiss-Prot: October 1, 1994
Last sequence update: October 1, 1994
Last modified: August 30, 2017
This is version 139 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Escherichia coli
    Escherichia coli (strain K12): entries and cross-references to EcoGene
  2. SIMILARITY comments
    Index of protein domains and families