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P37274 (PHOA_PENCH) Reviewed, UniProtKB/Swiss-Prot

Last modified April 3, 2013. Version 55. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Phosphate-repressible acid phosphatase
EC=3.1.3.2
Gene names
Name:PHOA
OrganismPenicillium chrysogenum (Penicillium notatum)
Taxonomic identifier5076 [NCBI]
Taxonomic lineageEukaryota › Fungi › Dikarya › Ascomycota › Pezizomycotina › Eurotiomycetes › Eurotiomycetidae › Eurotiales › Trichocomaceae › mitosporic Trichocomaceae › Penicillium › Penicillium chrysogenum complex

Protein attributes

Sequence length412 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is further processed into a mature form.
Protein existenceEvidence at protein level

General annotation (Comments)

Catalytic activity

A phosphate monoester + H2O = an alcohol + phosphate.

Subcellular location

Secreted.

Post-translational modification

The N-terminus is blocked.

Ontologies

Keywords
   Cellular componentSecreted
   DomainSignal
   Molecular functionHydrolase
   PTMGlycoprotein
   Technical termDirect protein sequencing
Gene Ontology (GO)
   Cellular_componentextracellular region

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionacid phosphatase activity

Inferred from electronic annotation. Source: EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Signal peptide1 – 1919 Potential
Chain20 – 412393Phosphate-repressible acid phosphatase
PRO_0000023979

Sites

Active site2151Proton donor By similarity

Amino acid modifications

Glycosylation741N-linked (GlcNAc...) Potential
Glycosylation1211N-linked (GlcNAc...) Potential
Glycosylation1861N-linked (GlcNAc...) Potential
Glycosylation2081N-linked (GlcNAc...) Potential
Glycosylation2171N-linked (GlcNAc...) Potential
Glycosylation3321N-linked (GlcNAc...) Potential
Glycosylation3431N-linked (GlcNAc...) Potential

Sequences

Sequence LengthMass (Da)Tools
P37274 [UniParc].

Last modified October 1, 1994. Version 1.
Checksum: 5659A7F07B1DDFD9

FASTA41245,628
        10         20         30         40         50         60 
MLTKQTLLAF VGALALATGT TTTEETPTQA EIDAARATAL PYSPVSNVKG LAFDRFVNIW 

        70         80         90        100        110        120 
LENTDFEPAA LDENLSKLAK EGILLTNYFA ISHPSQPNYC ASAGGDTFGM DNDDFLQIPS 

       130        140        150        160        170        180 
NVSTIADLFD TKHISWGEYQ EDMPYAGYQG KRYPLSGPNQ YVRKHNPLVL FNSVTDDAVR 

       190        200        210        220        230        240 
PRQIKNFTTF YDDLKHHSLP QHMFITPNMT NDAHDTNITV AGNWVDRFLS PLLKNEYFTK 

       250        260        270        280        290        300 
DSLVLLTFDE GDTYSYPNRV FSFLVGGAIP EHLKGTTDDT FYTHYSIVAS LSANWGLPSL 

       310        320        330        340        350        360 
GRWDCGANLL KMVADKTGYV NWEVDTSNVY LNETYPGPMS TDNYSSKWAV PATKGKCSAG 

       370        380        390        400        410 
HGIAEVVKNT YHGLQPTYDY ASPVPYDVTS GNNVGIKYHR TLVCILSCSS LS

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References

[1]"Isolation and analysis of the Penicillium chrysogenum phoA gene encoding a secreted phosphate-repressible acid phosphatase."
Haas H., Redl B., Friedlin E., Stoeffler G.
Gene 113:129-133(1992) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA], PARTIAL PROTEIN SEQUENCE.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		M80366 Genomic DNA. Translation: AAA33693.1.
PIRJN0319.

3D structure databases

ProteinModelPortalP37274.
ModBaseSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Phylogenomic databases

PhylomeDBP37274.

Family and domain databases

InterProIPR007312. Phosphoesterase.
[Graphical view]
PfamPF04185. Phosphoesterase. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry namePHOA_PENCH
AccessionPrimary (citable) accession number: P37274
Entry history
Integrated into UniProtKB/Swiss-Prot: October 1, 1994
Last sequence update: October 1, 1994
Last modified: April 3, 2013
This is version 55 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program
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