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P37274

- PHOA_PENCH

UniProt

P37274 - PHOA_PENCH

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Protein

Phosphate-repressible acid phosphatase

Gene
PHOA
Organism
Penicillium chrysogenum (Penicillium notatum)
Status
Reviewed - Annotation score: 2 out of 5 - Experimental evidence at protein leveli

Functioni

Catalytic activityi

A phosphate monoester + H2O = an alcohol + phosphate.

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei215 – 2151Proton donor By similarity

GO - Molecular functioni

  1. acid phosphatase activity Source: UniProtKB-EC
Complete GO annotation...

Keywords - Molecular functioni

Hydrolase

Names & Taxonomyi

Protein namesi
Recommended name:
Phosphate-repressible acid phosphatase (EC:3.1.3.2)
Gene namesi
Name:PHOA
OrganismiPenicillium chrysogenum (Penicillium notatum)
Taxonomic identifieri5076 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaPezizomycotinaEurotiomycetesEurotiomycetidaeEurotialesAspergillaceaePenicilliumPenicillium chrysogenum complex

Subcellular locationi

GO - Cellular componenti

  1. extracellular region Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Secreted

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Signal peptidei1 – 1919 Reviewed predictionAdd
BLAST
Chaini20 – 412393Phosphate-repressible acid phosphatasePRO_0000023979Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Glycosylationi74 – 741N-linked (GlcNAc...) Reviewed prediction
Glycosylationi121 – 1211N-linked (GlcNAc...) Reviewed prediction
Glycosylationi186 – 1861N-linked (GlcNAc...) Reviewed prediction
Glycosylationi208 – 2081N-linked (GlcNAc...) Reviewed prediction
Glycosylationi217 – 2171N-linked (GlcNAc...) Reviewed prediction
Glycosylationi332 – 3321N-linked (GlcNAc...) Reviewed prediction
Glycosylationi343 – 3431N-linked (GlcNAc...) Reviewed prediction

Post-translational modificationi

The N-terminus is blocked.

Keywords - PTMi

Glycoprotein

Structurei

3D structure databases

ProteinModelPortaliP37274.

Family & Domainsi

Keywords - Domaini

Signal

Phylogenomic databases

PhylomeDBiP37274.

Family and domain databases

InterProiIPR007312. Phosphoesterase.
[Graphical view]
PfamiPF04185. Phosphoesterase. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

P37274-1 [UniParc]FASTAAdd to Basket

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MLTKQTLLAF VGALALATGT TTTEETPTQA EIDAARATAL PYSPVSNVKG    50
LAFDRFVNIW LENTDFEPAA LDENLSKLAK EGILLTNYFA ISHPSQPNYC 100
ASAGGDTFGM DNDDFLQIPS NVSTIADLFD TKHISWGEYQ EDMPYAGYQG 150
KRYPLSGPNQ YVRKHNPLVL FNSVTDDAVR PRQIKNFTTF YDDLKHHSLP 200
QHMFITPNMT NDAHDTNITV AGNWVDRFLS PLLKNEYFTK DSLVLLTFDE 250
GDTYSYPNRV FSFLVGGAIP EHLKGTTDDT FYTHYSIVAS LSANWGLPSL 300
GRWDCGANLL KMVADKTGYV NWEVDTSNVY LNETYPGPMS TDNYSSKWAV 350
PATKGKCSAG HGIAEVVKNT YHGLQPTYDY ASPVPYDVTS GNNVGIKYHR 400
TLVCILSCSS LS 412
Length:412
Mass (Da):45,628
Last modified:October 1, 1994 - v1
Checksum:i5659A7F07B1DDFD9
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
M80366 Genomic DNA. Translation: AAA33693.1.
PIRiJN0319.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
M80366 Genomic DNA. Translation: AAA33693.1 .
PIRi JN0319.

3D structure databases

ProteinModelPortali P37274.
ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Phylogenomic databases

PhylomeDBi P37274.

Family and domain databases

InterProi IPR007312. Phosphoesterase.
[Graphical view ]
Pfami PF04185. Phosphoesterase. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Isolation and analysis of the Penicillium chrysogenum phoA gene encoding a secreted phosphate-repressible acid phosphatase."
    Haas H., Redl B., Friedlin E., Stoeffler G.
    Gene 113:129-133(1992) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA], PARTIAL PROTEIN SEQUENCE.

Entry informationi

Entry nameiPHOA_PENCH
AccessioniPrimary (citable) accession number: P37274
Entry historyi
Integrated into UniProtKB/Swiss-Prot: October 1, 1994
Last sequence update: October 1, 1994
Last modified: April 16, 2014
This is version 59 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Direct protein sequencing

External Data

Dasty 3

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