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P37274

- PHOA_PENCH

UniProt

P37274 - PHOA_PENCH

Protein

Phosphate-repressible acid phosphatase

Gene

PHOA

Organism
Penicillium chrysogenum (Penicillium notatum)
Status
Reviewed - Annotation score: 2 out of 5- Experimental evidence at protein leveli
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    • History
      Entry version 60 (01 Oct 2014)
      Sequence version 1 (01 Oct 1994)
      Previous versions | rss
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    Functioni

    Catalytic activityi

    A phosphate monoester + H2O = an alcohol + phosphate.

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Active sitei215 – 2151Proton donorBy similarity

    GO - Molecular functioni

    1. acid phosphatase activity Source: UniProtKB-EC

    Keywords - Molecular functioni

    Hydrolase

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Phosphate-repressible acid phosphatase (EC:3.1.3.2)
    Gene namesi
    Name:PHOA
    OrganismiPenicillium chrysogenum (Penicillium notatum)
    Taxonomic identifieri5076 [NCBI]
    Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaPezizomycotinaEurotiomycetesEurotiomycetidaeEurotialesAspergillaceaePenicilliumPenicillium chrysogenum complex

    Subcellular locationi

    GO - Cellular componenti

    1. extracellular region Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Secreted

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Signal peptidei1 – 1919Sequence AnalysisAdd
    BLAST
    Chaini20 – 412393Phosphate-repressible acid phosphatasePRO_0000023979Add
    BLAST

    Amino acid modifications

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Glycosylationi74 – 741N-linked (GlcNAc...)Sequence Analysis
    Glycosylationi121 – 1211N-linked (GlcNAc...)Sequence Analysis
    Glycosylationi186 – 1861N-linked (GlcNAc...)Sequence Analysis
    Glycosylationi208 – 2081N-linked (GlcNAc...)Sequence Analysis
    Glycosylationi217 – 2171N-linked (GlcNAc...)Sequence Analysis
    Glycosylationi332 – 3321N-linked (GlcNAc...)Sequence Analysis
    Glycosylationi343 – 3431N-linked (GlcNAc...)Sequence Analysis

    Post-translational modificationi

    The N-terminus is blocked.

    Keywords - PTMi

    Glycoprotein

    Structurei

    3D structure databases

    ProteinModelPortaliP37274.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Keywords - Domaini

    Signal

    Phylogenomic databases

    PhylomeDBiP37274.

    Family and domain databases

    InterProiIPR007312. Phosphoesterase.
    [Graphical view]
    PfamiPF04185. Phosphoesterase. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Sequence processingi: The displayed sequence is further processed into a mature form.

    P37274-1 [UniParc]FASTAAdd to Basket

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    MLTKQTLLAF VGALALATGT TTTEETPTQA EIDAARATAL PYSPVSNVKG    50
    LAFDRFVNIW LENTDFEPAA LDENLSKLAK EGILLTNYFA ISHPSQPNYC 100
    ASAGGDTFGM DNDDFLQIPS NVSTIADLFD TKHISWGEYQ EDMPYAGYQG 150
    KRYPLSGPNQ YVRKHNPLVL FNSVTDDAVR PRQIKNFTTF YDDLKHHSLP 200
    QHMFITPNMT NDAHDTNITV AGNWVDRFLS PLLKNEYFTK DSLVLLTFDE 250
    GDTYSYPNRV FSFLVGGAIP EHLKGTTDDT FYTHYSIVAS LSANWGLPSL 300
    GRWDCGANLL KMVADKTGYV NWEVDTSNVY LNETYPGPMS TDNYSSKWAV 350
    PATKGKCSAG HGIAEVVKNT YHGLQPTYDY ASPVPYDVTS GNNVGIKYHR 400
    TLVCILSCSS LS 412
    Length:412
    Mass (Da):45,628
    Last modified:October 1, 1994 - v1
    Checksum:i5659A7F07B1DDFD9
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    M80366 Genomic DNA. Translation: AAA33693.1.
    PIRiJN0319.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    M80366 Genomic DNA. Translation: AAA33693.1 .
    PIRi JN0319.

    3D structure databases

    ProteinModelPortali P37274.
    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Phylogenomic databases

    PhylomeDBi P37274.

    Family and domain databases

    InterProi IPR007312. Phosphoesterase.
    [Graphical view ]
    Pfami PF04185. Phosphoesterase. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Isolation and analysis of the Penicillium chrysogenum phoA gene encoding a secreted phosphate-repressible acid phosphatase."
      Haas H., Redl B., Friedlin E., Stoeffler G.
      Gene 113:129-133(1992) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA], PARTIAL PROTEIN SEQUENCE.

    Entry informationi

    Entry nameiPHOA_PENCH
    AccessioniPrimary (citable) accession number: P37274
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: October 1, 1994
    Last sequence update: October 1, 1994
    Last modified: October 1, 2014
    This is version 60 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programFungal Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Direct protein sequencing

    External Data

    Dasty 3