ID   PSY2_SOLLC              Reviewed;         310 AA.
AC   P37273;
DT   01-OCT-1994, integrated into UniProtKB/Swiss-Prot.
DT   01-OCT-1994, sequence version 1.
DT   24-JAN-2024, entry version 103.
DE   RecName: Full=Phytoene synthase 2, chloroplastic;
DE            EC=2.5.1.32;
DE   Flags: Precursor; Fragment;
GN   Name=PSY2;
OS   Solanum lycopersicum (Tomato) (Lycopersicon esculentum).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   asterids; lamiids; Solanales; Solanaceae; Solanoideae; Solaneae; Solanum;
OC   Solanum subgen. Lycopersicon.
OX   NCBI_TaxID=4081;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA].
RC   TISSUE=Leaf;
RX   PubMed=8245008; DOI=10.1016/s0021-9258(19)74448-2;
RA   Bartley G.E., Scolnik P.A.;
RT   "cDNA cloning, expression during development, and genome mapping of PSY2, a
RT   second tomato gene encoding phytoene synthase.";
RL   J. Biol. Chem. 268:25718-25721(1993).
CC   -!- FUNCTION: Catalyzes the reaction from prephytoene diphosphate to
CC       phytoene.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=2 (2E,6E,10E)-geranylgeranyl diphosphate = 15-cis-phytoene + 2
CC         diphosphate; Xref=Rhea:RHEA:34475, ChEBI:CHEBI:27787,
CC         ChEBI:CHEBI:33019, ChEBI:CHEBI:58756; EC=2.5.1.32;
CC   -!- PATHWAY: Carotenoid biosynthesis; phytoene biosynthesis; all-trans-
CC       phytoene from geranylgeranyl diphosphate: step 1/1.
CC   -!- SUBUNIT: Monomer. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Plastid, chloroplast.
CC   -!- DEVELOPMENTAL STAGE: In mature leaves.
CC   -!- SIMILARITY: Belongs to the phytoene/squalene synthase family.
CC       {ECO:0000305}.
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DR   EMBL; L23424; AAA34187.1; -; mRNA.
DR   PIR; A49558; A49558.
DR   AlphaFoldDB; P37273; -.
DR   SMR; P37273; -.
DR   STRING; 4081.P37273; -.
DR   PaxDb; 4081-Solyc02g081330-2-1; -.
DR   eggNOG; KOG1459; Eukaryota.
DR   InParanoid; P37273; -.
DR   SABIO-RK; P37273; -.
DR   UniPathway; UPA00799; UER00773.
DR   Proteomes; UP000004994; Unplaced.
DR   ExpressionAtlas; P37273; baseline and differential.
DR   GO; GO:0009507; C:chloroplast; IEA:UniProtKB-SubCell.
DR   GO; GO:0004311; F:farnesyltranstransferase activity; IEA:InterPro.
DR   GO; GO:0016767; F:geranylgeranyl-diphosphate geranylgeranyltransferase activity; IBA:GO_Central.
DR   GO; GO:0016117; P:carotenoid biosynthetic process; IBA:GO_Central.
DR   CDD; cd00683; Trans_IPPS_HH; 1.
DR   Gene3D; 1.10.600.10; Farnesyl Diphosphate Synthase; 1.
DR   InterPro; IPR008949; Isoprenoid_synthase_dom_sf.
DR   InterPro; IPR002060; Squ/phyt_synthse.
DR   InterPro; IPR019845; Squalene/phytoene_synthase_CS.
DR   InterPro; IPR044843; Trans_IPPS_bact-type.
DR   InterPro; IPR033904; Trans_IPPS_HH.
DR   PANTHER; PTHR31480; BIFUNCTIONAL LYCOPENE CYCLASE/PHYTOENE SYNTHASE; 1.
DR   PANTHER; PTHR31480:SF2; PHYTOENE SYNTHASE, CHLOROPLASTIC; 1.
DR   Pfam; PF00494; SQS_PSY; 1.
DR   SFLD; SFLDG01212; Phytoene_synthase_like; 1.
DR   SFLD; SFLDG01018; Squalene/Phytoene_Synthase_Lik; 1.
DR   SUPFAM; SSF48576; Terpenoid synthases; 1.
DR   PROSITE; PS01044; SQUALEN_PHYTOEN_SYN_1; 1.
DR   PROSITE; PS01045; SQUALEN_PHYTOEN_SYN_2; 1.
PE   2: Evidence at transcript level;
KW   Carotenoid biosynthesis; Chloroplast; Isoprene biosynthesis; Plastid;
KW   Reference proteome; Transferase; Transit peptide.
FT   TRANSIT         <1..25
FT                   /note="Chloroplast"
FT                   /evidence="ECO:0000255"
FT   CHAIN           26..310
FT                   /note="Phytoene synthase 2, chloroplastic"
FT                   /id="PRO_0000029857"
FT   NON_TER         1
SQ   SEQUENCE   310 AA;  35224 MW;  8EAF60FE1D9F4CF5 CRC64;
     DPDIVLPGNL GLLSEAYDRC GEVCAEYAKT FYLGTMLMTP DRRRAIWAIY VWCRRTDELV
     DGPNASHITP QALDRWEARL EDIFNGRPFD MLDAALSDTV SRFPVDIQPF RDMVEGMRMD
     LWKSRYNNFD ELYLYCYYVA GTVGLMSVPI MGIAPESKAT TESVYNAALA LGIANQLTNI
     LRDVGEDARR GRVYLPQDEL AQAGLSDEDI FAGKVTDKWR IFMKKQIQRA RKFFDEAEKG
     VTELSSASRW PVLASLLLYR KILDEIEAND YNNFTRRAYV SKPKKLLTLP IAYARSLVPP
     KSTSCPLAKT
//