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P37271

- PSY_ARATH

UniProt

P37271 - PSY_ARATH

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Protein

Phytoene synthase, chloroplastic

Gene

PSY1

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed - Annotation score: 3 out of 5- Experimental evidence at transcript leveli

Functioni

Catalyzes the reaction from prephytoene diphosphate to phytoene.

Catalytic activityi

2 geranylgeranyl diphosphate = 15-cis-phytoene + 2 diphosphate.

Pathwayi

GO - Molecular functioni

  1. geranylgeranyl-diphosphate geranylgeranyltransferase activity Source: UniProtKB-EC

GO - Biological processi

  1. carotenoid biosynthetic process Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

Transferase

Keywords - Biological processi

Carotenoid biosynthesis, Isoprene biosynthesis

Enzyme and pathway databases

BioCyciARA:AT5G17230-MONOMER.
ARA:GQT-752-MONOMER.
ARA:GQT-753-MONOMER.
MetaCyc:AT5G17230-MONOMER.
UniPathwayiUPA00799; UER00773.

Names & Taxonomyi

Protein namesi
Recommended name:
Phytoene synthase, chloroplastic (EC:2.5.1.32)
Gene namesi
Name:PSY1
Synonyms:PSY
Ordered Locus Names:At5g17230
ORF Names:MKP11.8
OrganismiArabidopsis thaliana (Mouse-ear cress)
Taxonomic identifieri3702 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
ProteomesiUP000006548: Chromosome 5

Organism-specific databases

TAIRiAT5G17230.

Subcellular locationi

GO - Cellular componenti

  1. chloroplast Source: UniProtKB-KW
Complete GO annotation...

Keywords - Cellular componenti

Chloroplast, Plastid

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transit peptidei1 – 7070ChloroplastSequence AnalysisAdd
BLAST
Chaini71 – 422352Phytoene synthase, chloroplasticPRO_0000029852Add
BLAST

Proteomic databases

PaxDbiP37271.
PRIDEiP37271.

Expressioni

Gene expression databases

ExpressionAtlasiP37271. baseline and differential.
GenevestigatoriP37271.

Interactioni

Subunit structurei

Monomer.By similarity

Protein-protein interaction databases

STRINGi3702.AT5G17230.3-P.

Structurei

3D structure databases

ProteinModelPortaliP37271.
SMRiP37271. Positions 132-389.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the phytoene/squalene synthase family.Curated

Keywords - Domaini

Transit peptide

Phylogenomic databases

eggNOGiCOG1562.
HOGENOMiHOG000220848.
InParanoidiP37271.
KOiK02291.
PhylomeDBiP37271.

Family and domain databases

Gene3Di1.10.600.10. 1 hit.
InterProiIPR002060. Squ/phyt_synthse.
IPR019845. Squalene/phytoene_synthase_CS.
IPR008949. Terpenoid_synth.
[Graphical view]
PfamiPF00494. SQS_PSY. 1 hit.
[Graphical view]
SUPFAMiSSF48576. SSF48576. 1 hit.
PROSITEiPS01044. SQUALEN_PHYTOEN_SYN_1. 1 hit.
PS01045. SQUALEN_PHYTOEN_SYN_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

This entry describes 1 isoform i produced by alternative splicing. Align

Note: A number of isoforms are produced. According to EST sequences.

Isoform 1 (identifier: P37271-1) [UniParc]FASTAAdd to Basket

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide

        10         20         30         40         50
MSSSVAVLWV ATSSLNPDPM NNCGLVRVLE SSRLFSPCQN QRLNKGKKKQ
60 70 80 90 100
IPTWSSSFVR NRSRRIGVVS SSLVASPSGE IALSSEEKVY NVVLKQAALV
110 120 130 140 150
NKQLRSSSYD LDVKKPQDVV LPGSLSLLGE AYDRCGEVCA EYAKTFYLGT
160 170 180 190 200
LLMTPERRKA IWAIYVWCRR TDELVDGPNA SHITPMALDR WEARLEDLFR
210 220 230 240 250
GRPFDMLDAA LADTVARYPV DIQPFRDMIE GMRMDLKKSR YQNFDDLYLY
260 270 280 290 300
CYYVAGTVGL MSVPVMGIDP KSKATTESVY NAALALGIAN QLTNILRDVG
310 320 330 340 350
EDARRGRVYL PQDELAQAGL SDEDIFAGKV TDKWRNFMKM QLKRARMFFD
360 370 380 390 400
EAEKGVTELS AASRWPVWAS LLLYRRILDE IEANDYNNFT KRAYVGKVKK
410 420
IAALPLAYAK SVLKTSSSRL SI
Length:422
Mass (Da):47,487
Last modified:January 10, 2003 - v2
Checksum:iC44F0A512F2DD31E
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Sequence conflicti60 – 601R → M in AAM62787. 1 PublicationCurated
Sequence conflicti128 – 1281L → LV in AAA32836. (PubMed:8016277)Curated
Sequence conflicti143 – 1431A → P in AAA32836. (PubMed:8016277)Curated

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
L25812 mRNA. Translation: AAA32836.1.
AF009954 Genomic DNA. Translation: AAB65697.1.
AB005238 Genomic DNA. Translation: BAB10510.1.
CP002688 Genomic DNA. Translation: AED92399.1.
CP002688 Genomic DNA. Translation: AED92400.1.
BT000450 mRNA. Translation: AAN17427.1.
BT002084 mRNA. Translation: AAN72095.1.
AY085565 mRNA. Translation: AAM62787.1.
RefSeqiNP_001031895.1. NM_001036818.2. [P37271-1]
NP_197225.1. NM_121729.2. [P37271-1]
UniGeneiAt.23726.

Genome annotation databases

EnsemblPlantsiAT5G17230.1; AT5G17230.1; AT5G17230. [P37271-1]
AT5G17230.2; AT5G17230.2; AT5G17230. [P37271-1]
GeneIDi831587.
KEGGiath:AT5G17230.

Keywords - Coding sequence diversityi

Alternative splicing

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
L25812 mRNA. Translation: AAA32836.1 .
AF009954 Genomic DNA. Translation: AAB65697.1 .
AB005238 Genomic DNA. Translation: BAB10510.1 .
CP002688 Genomic DNA. Translation: AED92399.1 .
CP002688 Genomic DNA. Translation: AED92400.1 .
BT000450 mRNA. Translation: AAN17427.1 .
BT002084 mRNA. Translation: AAN72095.1 .
AY085565 mRNA. Translation: AAM62787.1 .
RefSeqi NP_001031895.1. NM_001036818.2. [P37271-1 ]
NP_197225.1. NM_121729.2. [P37271-1 ]
UniGenei At.23726.

3D structure databases

ProteinModelPortali P37271.
SMRi P37271. Positions 132-389.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 3702.AT5G17230.3-P.

Proteomic databases

PaxDbi P37271.
PRIDEi P37271.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblPlantsi AT5G17230.1 ; AT5G17230.1 ; AT5G17230 . [P37271-1 ]
AT5G17230.2 ; AT5G17230.2 ; AT5G17230 . [P37271-1 ]
GeneIDi 831587.
KEGGi ath:AT5G17230.

Organism-specific databases

TAIRi AT5G17230.

Phylogenomic databases

eggNOGi COG1562.
HOGENOMi HOG000220848.
InParanoidi P37271.
KOi K02291.
PhylomeDBi P37271.

Enzyme and pathway databases

UniPathwayi UPA00799 ; UER00773 .
BioCyci ARA:AT5G17230-MONOMER.
ARA:GQT-752-MONOMER.
ARA:GQT-753-MONOMER.
MetaCyc:AT5G17230-MONOMER.

Gene expression databases

ExpressionAtlasi P37271. baseline and differential.
Genevestigatori P37271.

Family and domain databases

Gene3Di 1.10.600.10. 1 hit.
InterProi IPR002060. Squ/phyt_synthse.
IPR019845. Squalene/phytoene_synthase_CS.
IPR008949. Terpenoid_synth.
[Graphical view ]
Pfami PF00494. SQS_PSY. 1 hit.
[Graphical view ]
SUPFAMi SSF48576. SSF48576. 1 hit.
PROSITEi PS01044. SQUALEN_PHYTOEN_SYN_1. 1 hit.
PS01045. SQUALEN_PHYTOEN_SYN_2. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "Nucleotide sequence of an Arabidopsis cDNA for phytoene synthase."
    Scolnik P.A., Bartley G.E.
    Plant Physiol. 104:1471-1472(1994) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [MRNA].
    Strain: cv. Columbia.
  2. "Sequence of the phytoene synthase gene of Arabidopsis."
    Castrignano F., Giuliano G.
    Submitted (JUN-1997) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: cv. Columbia.
  3. "Structural analysis of Arabidopsis thaliana chromosome 5. I. Sequence features of the 1.6 Mb regions covered by twenty physically assigned P1 clones."
    Sato S., Kotani H., Nakamura Y., Kaneko T., Asamizu E., Fukami M., Miyajima N., Tabata S.
    DNA Res. 4:215-230(1997) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: cv. Columbia.
  4. The Arabidopsis Information Resource (TAIR)
    Submitted (APR-2011) to the EMBL/GenBank/DDBJ databases
    Cited for: GENOME REANNOTATION.
    Strain: cv. Columbia.
  5. "Empirical analysis of transcriptional activity in the Arabidopsis genome."
    Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M., Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G., Liu S.X., Lam B., Sakano H., Wu T., Yu G.
    , Miranda M., Quach H.L., Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C., Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J., Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A., Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C., Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X., Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M., Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K., Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A., Ecker J.R.
    Science 302:842-846(2003) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Strain: cv. Columbia.
  6. "Full-length cDNA from Arabidopsis thaliana."
    Brover V.V., Troukhan M.E., Alexandrov N.A., Lu Y.-P., Flavell R.B., Feldmann K.A.
    Submitted (MAR-2002) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].

Entry informationi

Entry nameiPSY_ARATH
AccessioniPrimary (citable) accession number: P37271
Secondary accession number(s): O22375, Q8LE86
Entry historyi
Integrated into UniProtKB/Swiss-Prot: October 1, 1994
Last sequence update: January 10, 2003
Last modified: October 29, 2014
This is version 120 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Multifunctional enzyme, Reference proteome

Documents

  1. Arabidopsis thaliana
    Arabidopsis thaliana: entries and gene names
  2. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  3. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3