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P37267 (CBP4_YEAST) Reviewed, UniProtKB/Swiss-Prot

Last modified May 14, 2014. Version 110. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (3) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Assembly factor CBP4
Alternative name(s):
Cytochrome b mRNA-processing protein 4
Gene names
Name:CBP4
Ordered Locus Names:YGR174C
ORF Names:G7122
OrganismSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) [Reference proteome]
Taxonomic identifier559292 [NCBI]
Taxonomic lineageEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces

Protein attributes

Sequence length147 AA.
Sequence statusComplete.
Protein existenceEvidence at protein level

General annotation (Comments)

Function

Essential for the assembly of ubiquinol-cytochrome c reductase. It has a direct effect on the correct occurrence of the Rieske protein, core 4, core 5 and apocytochrome b. Ref.1 Ref.9

Subcellular location

Mitochondrion inner membrane; Single-pass membrane protein Potential Ref.1 Ref.6 Ref.8.

Miscellaneous

Present with 704 molecules/cell in log phase SD medium.

Sequence similarities

Belongs to the CBP4 family.

Sequence caution

The sequence AAA61566.1 differs from that shown. Reason: Erroneous initiation. Translation N-terminally shortened.

The sequence AAT93181.1 differs from that shown. Reason: Erroneous initiation. Translation N-terminally shortened.

The sequence CAA97200.1 differs from that shown. Reason: Erroneous initiation. Translation N-terminally shortened.

The sequence DAA08269.1 differs from that shown. Reason: Erroneous initiation. Translation N-terminally shortened.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 147147Assembly factor CBP4
PRO_0000020845

Regions

Transmembrane5 – 2723Helical; Potential

Experimental info

Sequence conflict421S → F in AAA61566. Ref.1

Sequences

Sequence LengthMass (Da)Tools
P37267 [UniParc].

Last modified October 2, 2007. Version 3.
Checksum: 27CD71BD4C7CE8BB

FASTA14717,532
        10         20         30         40         50         60 
MERPLWVRWL KVYAIGGAII GSGFLLFKYT TPTDQQLISQ LSPELRLQYE REKKLRQSEQ 

        70         80         90        100        110        120 
QALMKIVKET SQSDDPIWKT GPLQSPWERN GDNVQSRDHF AKVRAEEVQK EELARIRNEL 

       130        140 
SQLRSETEEK TKEIVQDKQV KSWWRFW 

« Hide

References

« Hide 'large scale' references
[1]"Characterization of CBP4, a new gene essential for the expression of ubiquinol-cytochrome c reductase in Saccharomyces cerevisiae."
Crivellone M.D.
J. Biol. Chem. 269:21284-21292(1994) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA], FUNCTION, SUBCELLULAR LOCATION.
[2]"The nucleotide sequence of Saccharomyces cerevisiae chromosome VII."
Tettelin H., Agostoni-Carbone M.L., Albermann K., Albers M., Arroyo J., Backes U., Barreiros T., Bertani I., Bjourson A.J., Brueckner M., Bruschi C.V., Carignani G., Castagnoli L., Cerdan E., Clemente M.L., Coblenz A., Coglievina M., Coissac E. expand/collapse author list , Defoor E., Del Bino S., Delius H., Delneri D., de Wergifosse P., Dujon B., Durand P., Entian K.-D., Eraso P., Escribano V., Fabiani L., Fartmann B., Feroli F., Feuermann M., Frontali L., Garcia-Gonzalez M., Garcia-Saez M.I., Goffeau A., Guerreiro P., Hani J., Hansen M., Hebling U., Hernandez K., Heumann K., Hilger F., Hofmann B., Indge K.J., James C.M., Klima R., Koetter P., Kramer B., Kramer W., Lauquin G., Leuther H., Louis E.J., Maillier E., Marconi A., Martegani E., Mazon M.J., Mazzoni C., McReynolds A.D.K., Melchioretto P., Mewes H.-W., Minenkova O., Mueller-Auer S., Nawrocki A., Netter P., Neu R., Nombela C., Oliver S.G., Panzeri L., Paoluzi S., Plevani P., Portetelle D., Portillo F., Potier S., Purnelle B., Rieger M., Riles L., Rinaldi T., Robben J., Rodrigues-Pousada C., Rodriguez-Belmonte E., Rodriguez-Torres A.M., Rose M., Ruzzi M., Saliola M., Sanchez-Perez M., Schaefer B., Schaefer M., Scharfe M., Schmidheini T., Schreer A., Skala J., Souciet J.-L., Steensma H.Y., Talla E., Thierry A., Vandenbol M., van der Aart Q.J.M., Van Dyck L., Vanoni M., Verhasselt P., Voet M., Volckaert G., Wambutt R., Watson M.D., Weber N., Wedler E., Wedler H., Wipfli P., Wolf K., Wright L.F., Zaccaria P., Zimmermann M., Zollner A., Kleine K.
Nature 387:81-84(1997) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 204508 / S288c.
[3]"The reference genome sequence of Saccharomyces cerevisiae: Then and now."
Engel S.R., Dietrich F.S., Fisk D.G., Binkley G., Balakrishnan R., Costanzo M.C., Dwight S.S., Hitz B.C., Karra K., Nash R.S., Weng S., Wong E.D., Lloyd P., Skrzypek M.S., Miyasato S.R., Simison M., Cherry J.M.
G3 (Bethesda) 4:389-398(2014) [PubMed] [Europe PMC] [Abstract]
Cited for: GENOME REANNOTATION.
Strain: ATCC 204508 / S288c.
[4]"Approaching a complete repository of sequence-verified protein-encoding clones for Saccharomyces cerevisiae."
Hu Y., Rolfs A., Bhullar B., Murthy T.V.S., Zhu C., Berger M.F., Camargo A.A., Kelley F., McCarron S., Jepson D., Richardson A., Raphael J., Moreira D., Taycher E., Zuo D., Mohr S., Kane M.F., Williamson J. expand/collapse author list , Simpson A.J.G., Bulyk M.L., Harlow E., Marsischky G., Kolodner R.D., LaBaer J.
Genome Res. 17:536-543(2007) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
Strain: ATCC 204508 / S288c.
[5]"Verification of 3' and 5' ends of S.cerevisiae transcripts."
Kennedy M.C., Dietrich F.S.
Submitted (SEP-2003) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 1-43 AND 91-147.
Strain: ATCC 204511 / S288c / AB972.
[6]"Global analysis of protein localization in budding yeast."
Huh W.-K., Falvo J.V., Gerke L.C., Carroll A.S., Howson R.W., Weissman J.S., O'Shea E.K.
Nature 425:686-691(2003) [PubMed] [Europe PMC] [Abstract]
Cited for: SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS].
[7]"Global analysis of protein expression in yeast."
Ghaemmaghami S., Huh W.-K., Bower K., Howson R.W., Belle A., Dephoure N., O'Shea E.K., Weissman J.S.
Nature 425:737-741(2003) [PubMed] [Europe PMC] [Abstract]
Cited for: LEVEL OF PROTEIN EXPRESSION [LARGE SCALE ANALYSIS].
[8]"The proteome of Saccharomyces cerevisiae mitochondria."
Sickmann A., Reinders J., Wagner Y., Joppich C., Zahedi R.P., Meyer H.E., Schoenfisch B., Perschil I., Chacinska A., Guiard B., Rehling P., Pfanner N., Meisinger C.
Proc. Natl. Acad. Sci. U.S.A. 100:13207-13212(2003) [PubMed] [Europe PMC] [Abstract]
Cited for: SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS].
Strain: ATCC 76625 / YPH499.
[9]"Organization of assembly factors Cbp3p and Cbp4p and their effect on bc(1) complex assembly in Saccharomyces cerevisiae."
Kronekova Z., Rodel G.
Curr. Genet. 47:203-212(2005) [PubMed] [Europe PMC] [Abstract]
Cited for: FUNCTION, INTERACTION WITH CBP3.
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
U10700 Genomic DNA. Translation: AAA61566.1. Different initiation.
Z72959 Genomic DNA. Translation: CAA97200.1. Different initiation.
AY693162 Genomic DNA. Translation: AAT93181.1. Different initiation.
AY389299 mRNA. Translation: AAQ97231.1.
AY389298 mRNA. Translation: AAQ97230.1.
BK006941 Genomic DNA. Translation: DAA08269.1. Different initiation.
PIRS64488.
RefSeqNP_011690.3. NM_001181303.3.

3D structure databases

ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

BioGrid33427. 88 interactions.
DIPDIP-4216N.
IntActP37267. 2 interactions.
MINTMINT-574347.

Proteomic databases

MaxQBP37267.
PaxDbP37267.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID853085.
KEGGsce:YGR174C.

Organism-specific databases

CYGDYGR174c.
SGDS000003406. CBP4.

Phylogenomic databases

eggNOGNOG83063.
HOGENOMHOG000065984.
OrthoDBEOG7CZKKB.

Enzyme and pathway databases

BioCycYEAST:G3O-30870-MONOMER.

Gene expression databases

GenevestigatorP37267.

Family and domain databases

InterProIPR012420. Cbp4.
[Graphical view]
PfamPF07960. CBP4. 1 hit.
[Graphical view]
ProtoNetSearch...

Other

NextBio973061.

Entry information

Entry nameCBP4_YEAST
AccessionPrimary (citable) accession number: P37267
Secondary accession number(s): D6VUV8, Q6TQT9, Q6TQU0
Entry history
Integrated into UniProtKB/Swiss-Prot: October 1, 1994
Last sequence update: October 2, 2007
Last modified: May 14, 2014
This is version 110 of the entry and version 3 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Relevant documents

Yeast chromosome VII

Yeast (Saccharomyces cerevisiae) chromosome VII: entries and gene names

Yeast

Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD

SIMILARITY comments

Index of protein domains and families