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P37267

- CBP4_YEAST

UniProt

P37267 - CBP4_YEAST

Protein

Assembly factor CBP4

Gene

CBP4

Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Status
Reviewed - Annotation score: 3 out of 5- Experimental evidence at protein leveli
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    • History
      Entry version 111 (01 Oct 2014)
      Sequence version 3 (02 Oct 2007)
      Previous versions | rss
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    Functioni

    Essential for the assembly of ubiquinol-cytochrome c reductase. It has a direct effect on the correct occurrence of the Rieske protein, core 4, core 5 and apocytochrome b.2 Publications

    GO - Biological processi

    1. mitochondrial respiratory chain complex III assembly Source: SGD

    Keywords - Molecular functioni

    Chaperone

    Enzyme and pathway databases

    BioCyciYEAST:G3O-30870-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Assembly factor CBP4
    Alternative name(s):
    Cytochrome b mRNA-processing protein 4
    Gene namesi
    Name:CBP4
    Ordered Locus Names:YGR174C
    ORF Names:G7122
    OrganismiSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
    Taxonomic identifieri559292 [NCBI]
    Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces
    ProteomesiUP000002311: Chromosome VII

    Organism-specific databases

    CYGDiYGR174c.
    SGDiS000003406. CBP4.

    Subcellular locationi

    GO - Cellular componenti

    1. integral component of mitochondrial membrane Source: SGD
    2. mitochondrial inner membrane Source: UniProtKB-SubCell
    3. mitochondrion Source: SGD

    Keywords - Cellular componenti

    Membrane, Mitochondrion, Mitochondrion inner membrane

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 147147Assembly factor CBP4PRO_0000020845Add
    BLAST

    Proteomic databases

    MaxQBiP37267.
    PaxDbiP37267.

    Expressioni

    Gene expression databases

    GenevestigatoriP37267.

    Interactioni

    Protein-protein interaction databases

    BioGridi33427. 88 interactions.
    DIPiDIP-4216N.
    IntActiP37267. 2 interactions.
    MINTiMINT-574347.

    Structurei

    Transmembrane

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Transmembranei5 – 2723HelicalSequence AnalysisAdd
    BLAST

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the CBP4 family.Curated

    Keywords - Domaini

    Transmembrane, Transmembrane helix

    Phylogenomic databases

    eggNOGiNOG83063.
    HOGENOMiHOG000065984.
    OrthoDBiEOG7CZKKB.

    Family and domain databases

    InterProiIPR012420. Cbp4.
    [Graphical view]
    PfamiPF07960. CBP4. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    P37267-1 [UniParc]FASTAAdd to Basket

    « Hide

    MERPLWVRWL KVYAIGGAII GSGFLLFKYT TPTDQQLISQ LSPELRLQYE    50
    REKKLRQSEQ QALMKIVKET SQSDDPIWKT GPLQSPWERN GDNVQSRDHF 100
    AKVRAEEVQK EELARIRNEL SQLRSETEEK TKEIVQDKQV KSWWRFW 147
    Length:147
    Mass (Da):17,532
    Last modified:October 2, 2007 - v3
    Checksum:i27CD71BD4C7CE8BB
    GO

    Sequence cautioni

    The sequence AAA61566.1 differs from that shown. Reason: Erroneous initiation. Translation N-terminally shortened.
    The sequence AAT93181.1 differs from that shown. Reason: Erroneous initiation. Translation N-terminally shortened.
    The sequence CAA97200.1 differs from that shown. Reason: Erroneous initiation. Translation N-terminally shortened.
    The sequence DAA08269.1 differs from that shown. Reason: Erroneous initiation. Translation N-terminally shortened.

    Experimental Info

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Sequence conflicti42 – 421S → F in AAA61566. (PubMed:8063753)Curated

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    U10700 Genomic DNA. Translation: AAA61566.1. Different initiation.
    Z72959 Genomic DNA. Translation: CAA97200.1. Different initiation.
    AY693162 Genomic DNA. Translation: AAT93181.1. Different initiation.
    AY389299 mRNA. Translation: AAQ97231.1.
    AY389298 mRNA. Translation: AAQ97230.1.
    BK006941 Genomic DNA. Translation: DAA08269.1. Different initiation.
    PIRiS64488.
    RefSeqiNP_011690.3. NM_001181303.3.

    Genome annotation databases

    GeneIDi853085.
    KEGGisce:YGR174C.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    U10700 Genomic DNA. Translation: AAA61566.1 . Different initiation.
    Z72959 Genomic DNA. Translation: CAA97200.1 . Different initiation.
    AY693162 Genomic DNA. Translation: AAT93181.1 . Different initiation.
    AY389299 mRNA. Translation: AAQ97231.1 .
    AY389298 mRNA. Translation: AAQ97230.1 .
    BK006941 Genomic DNA. Translation: DAA08269.1 . Different initiation.
    PIRi S64488.
    RefSeqi NP_011690.3. NM_001181303.3.

    3D structure databases

    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    BioGridi 33427. 88 interactions.
    DIPi DIP-4216N.
    IntActi P37267. 2 interactions.
    MINTi MINT-574347.

    Proteomic databases

    MaxQBi P37267.
    PaxDbi P37267.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    GeneIDi 853085.
    KEGGi sce:YGR174C.

    Organism-specific databases

    CYGDi YGR174c.
    SGDi S000003406. CBP4.

    Phylogenomic databases

    eggNOGi NOG83063.
    HOGENOMi HOG000065984.
    OrthoDBi EOG7CZKKB.

    Enzyme and pathway databases

    BioCyci YEAST:G3O-30870-MONOMER.

    Miscellaneous databases

    NextBioi 973061.

    Gene expression databases

    Genevestigatori P37267.

    Family and domain databases

    InterProi IPR012420. Cbp4.
    [Graphical view ]
    Pfami PF07960. CBP4. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Characterization of CBP4, a new gene essential for the expression of ubiquinol-cytochrome c reductase in Saccharomyces cerevisiae."
      Crivellone M.D.
      J. Biol. Chem. 269:21284-21292(1994) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA], FUNCTION, SUBCELLULAR LOCATION.
    2. "The nucleotide sequence of Saccharomyces cerevisiae chromosome VII."
      Tettelin H., Agostoni-Carbone M.L., Albermann K., Albers M., Arroyo J., Backes U., Barreiros T., Bertani I., Bjourson A.J., Brueckner M., Bruschi C.V., Carignani G., Castagnoli L., Cerdan E., Clemente M.L., Coblenz A., Coglievina M., Coissac E.
      , Defoor E., Del Bino S., Delius H., Delneri D., de Wergifosse P., Dujon B., Durand P., Entian K.-D., Eraso P., Escribano V., Fabiani L., Fartmann B., Feroli F., Feuermann M., Frontali L., Garcia-Gonzalez M., Garcia-Saez M.I., Goffeau A., Guerreiro P., Hani J., Hansen M., Hebling U., Hernandez K., Heumann K., Hilger F., Hofmann B., Indge K.J., James C.M., Klima R., Koetter P., Kramer B., Kramer W., Lauquin G., Leuther H., Louis E.J., Maillier E., Marconi A., Martegani E., Mazon M.J., Mazzoni C., McReynolds A.D.K., Melchioretto P., Mewes H.-W., Minenkova O., Mueller-Auer S., Nawrocki A., Netter P., Neu R., Nombela C., Oliver S.G., Panzeri L., Paoluzi S., Plevani P., Portetelle D., Portillo F., Potier S., Purnelle B., Rieger M., Riles L., Rinaldi T., Robben J., Rodrigues-Pousada C., Rodriguez-Belmonte E., Rodriguez-Torres A.M., Rose M., Ruzzi M., Saliola M., Sanchez-Perez M., Schaefer B., Schaefer M., Scharfe M., Schmidheini T., Schreer A., Skala J., Souciet J.-L., Steensma H.Y., Talla E., Thierry A., Vandenbol M., van der Aart Q.J.M., Van Dyck L., Vanoni M., Verhasselt P., Voet M., Volckaert G., Wambutt R., Watson M.D., Weber N., Wedler E., Wedler H., Wipfli P., Wolf K., Wright L.F., Zaccaria P., Zimmermann M., Zollner A., Kleine K.
      Nature 387:81-84(1997) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: ATCC 204508 / S288c.
    3. Cited for: GENOME REANNOTATION.
      Strain: ATCC 204508 / S288c.
    4. Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
      Strain: ATCC 204508 / S288c.
    5. "Verification of 3' and 5' ends of S.cerevisiae transcripts."
      Kennedy M.C., Dietrich F.S.
      Submitted (SEP-2003) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 1-43 AND 91-147.
      Strain: ATCC 204511 / S288c / AB972.
    6. Cited for: SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS].
    7. Cited for: LEVEL OF PROTEIN EXPRESSION [LARGE SCALE ANALYSIS].
    8. Cited for: SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS].
      Strain: ATCC 76625 / YPH499.
    9. "Organization of assembly factors Cbp3p and Cbp4p and their effect on bc(1) complex assembly in Saccharomyces cerevisiae."
      Kronekova Z., Rodel G.
      Curr. Genet. 47:203-212(2005) [PubMed] [Europe PMC] [Abstract]
      Cited for: FUNCTION, INTERACTION WITH CBP3.

    Entry informationi

    Entry nameiCBP4_YEAST
    AccessioniPrimary (citable) accession number: P37267
    Secondary accession number(s): D6VUV8, Q6TQT9, Q6TQU0
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: October 1, 1994
    Last sequence update: October 2, 2007
    Last modified: October 1, 2014
    This is version 111 of the entry and version 3 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programFungal Protein Annotation Program

    Miscellaneousi

    Miscellaneous

    Present with 704 molecules/cell in log phase SD medium.1 Publication

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. SIMILARITY comments
      Index of protein domains and families
    2. Yeast
      Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD
    3. Yeast chromosome VII
      Yeast (Saccharomyces cerevisiae) chromosome VII: entries and gene names

    External Data

    Dasty 3