Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

P37267

- CBP4_YEAST

UniProt

P37267 - CBP4_YEAST

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein

Assembly factor CBP4

Gene

CBP4

Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Status
Reviewed - Annotation score: 3 out of 5- Experimental evidence at protein leveli

Functioni

Essential for the assembly of ubiquinol-cytochrome c reductase. It has a direct effect on the correct occurrence of the Rieske protein, core 4, core 5 and apocytochrome b.2 Publications

GO - Biological processi

  1. mitochondrial respiratory chain complex III assembly Source: SGD
Complete GO annotation...

Keywords - Molecular functioni

Chaperone

Enzyme and pathway databases

BioCyciYEAST:G3O-30870-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Assembly factor CBP4
Alternative name(s):
Cytochrome b mRNA-processing protein 4
Gene namesi
Name:CBP4
Ordered Locus Names:YGR174C
ORF Names:G7122
OrganismiSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Taxonomic identifieri559292 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces
ProteomesiUP000002311: Chromosome VII

Organism-specific databases

CYGDiYGR174c.
SGDiS000003406. CBP4.

Subcellular locationi

GO - Cellular componenti

  1. integral component of mitochondrial membrane Source: SGD
  2. mitochondrial inner membrane Source: UniProtKB-KW
  3. mitochondrion Source: SGD
Complete GO annotation...

Keywords - Cellular componenti

Membrane, Mitochondrion, Mitochondrion inner membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 147147Assembly factor CBP4PRO_0000020845Add
BLAST

Proteomic databases

MaxQBiP37267.
PaxDbiP37267.

Expressioni

Gene expression databases

GenevestigatoriP37267.

Interactioni

Protein-protein interaction databases

BioGridi33427. 88 interactions.
DIPiDIP-4216N.
IntActiP37267. 2 interactions.
MINTiMINT-574347.

Structurei

Transmembrane

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei5 – 2723HelicalSequence AnalysisAdd
BLAST

Family & Domainsi

Sequence similaritiesi

Belongs to the CBP4 family.Curated

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiNOG83063.
HOGENOMiHOG000065984.
InParanoidiP37267.
OrthoDBiEOG7CZKKB.

Family and domain databases

InterProiIPR012420. Cbp4.
[Graphical view]
PfamiPF07960. CBP4. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P37267-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MERPLWVRWL KVYAIGGAII GSGFLLFKYT TPTDQQLISQ LSPELRLQYE
60 70 80 90 100
REKKLRQSEQ QALMKIVKET SQSDDPIWKT GPLQSPWERN GDNVQSRDHF
110 120 130 140
AKVRAEEVQK EELARIRNEL SQLRSETEEK TKEIVQDKQV KSWWRFW
Length:147
Mass (Da):17,532
Last modified:October 2, 2007 - v3
Checksum:i27CD71BD4C7CE8BB
GO

Sequence cautioni

The sequence AAA61566.1 differs from that shown. Reason: Erroneous initiation. Translation N-terminally shortened.
The sequence AAT93181.1 differs from that shown. Reason: Erroneous initiation. Translation N-terminally shortened.
The sequence CAA97200.1 differs from that shown. Reason: Erroneous initiation. Translation N-terminally shortened.
The sequence DAA08269.1 differs from that shown. Reason: Erroneous initiation. Translation N-terminally shortened.

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Sequence conflicti42 – 421S → F in AAA61566. (PubMed:8063753)Curated

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
U10700 Genomic DNA. Translation: AAA61566.1. Different initiation.
Z72959 Genomic DNA. Translation: CAA97200.1. Different initiation.
AY693162 Genomic DNA. Translation: AAT93181.1. Different initiation.
AY389299 mRNA. Translation: AAQ97231.1.
AY389298 mRNA. Translation: AAQ97230.1.
BK006941 Genomic DNA. Translation: DAA08269.1. Different initiation.
PIRiS64488.
RefSeqiNP_011690.3. NM_001181303.3.

Genome annotation databases

GeneIDi853085.
KEGGisce:YGR174C.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
U10700 Genomic DNA. Translation: AAA61566.1 . Different initiation.
Z72959 Genomic DNA. Translation: CAA97200.1 . Different initiation.
AY693162 Genomic DNA. Translation: AAT93181.1 . Different initiation.
AY389299 mRNA. Translation: AAQ97231.1 .
AY389298 mRNA. Translation: AAQ97230.1 .
BK006941 Genomic DNA. Translation: DAA08269.1 . Different initiation.
PIRi S64488.
RefSeqi NP_011690.3. NM_001181303.3.

3D structure databases

ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

BioGridi 33427. 88 interactions.
DIPi DIP-4216N.
IntActi P37267. 2 interactions.
MINTi MINT-574347.

Proteomic databases

MaxQBi P37267.
PaxDbi P37267.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

GeneIDi 853085.
KEGGi sce:YGR174C.

Organism-specific databases

CYGDi YGR174c.
SGDi S000003406. CBP4.

Phylogenomic databases

eggNOGi NOG83063.
HOGENOMi HOG000065984.
InParanoidi P37267.
OrthoDBi EOG7CZKKB.

Enzyme and pathway databases

BioCyci YEAST:G3O-30870-MONOMER.

Miscellaneous databases

NextBioi 973061.

Gene expression databases

Genevestigatori P37267.

Family and domain databases

InterProi IPR012420. Cbp4.
[Graphical view ]
Pfami PF07960. CBP4. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "Characterization of CBP4, a new gene essential for the expression of ubiquinol-cytochrome c reductase in Saccharomyces cerevisiae."
    Crivellone M.D.
    J. Biol. Chem. 269:21284-21292(1994) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA], FUNCTION, SUBCELLULAR LOCATION.
  2. "The nucleotide sequence of Saccharomyces cerevisiae chromosome VII."
    Tettelin H., Agostoni-Carbone M.L., Albermann K., Albers M., Arroyo J., Backes U., Barreiros T., Bertani I., Bjourson A.J., Brueckner M., Bruschi C.V., Carignani G., Castagnoli L., Cerdan E., Clemente M.L., Coblenz A., Coglievina M., Coissac E.
    , Defoor E., Del Bino S., Delius H., Delneri D., de Wergifosse P., Dujon B., Durand P., Entian K.-D., Eraso P., Escribano V., Fabiani L., Fartmann B., Feroli F., Feuermann M., Frontali L., Garcia-Gonzalez M., Garcia-Saez M.I., Goffeau A., Guerreiro P., Hani J., Hansen M., Hebling U., Hernandez K., Heumann K., Hilger F., Hofmann B., Indge K.J., James C.M., Klima R., Koetter P., Kramer B., Kramer W., Lauquin G., Leuther H., Louis E.J., Maillier E., Marconi A., Martegani E., Mazon M.J., Mazzoni C., McReynolds A.D.K., Melchioretto P., Mewes H.-W., Minenkova O., Mueller-Auer S., Nawrocki A., Netter P., Neu R., Nombela C., Oliver S.G., Panzeri L., Paoluzi S., Plevani P., Portetelle D., Portillo F., Potier S., Purnelle B., Rieger M., Riles L., Rinaldi T., Robben J., Rodrigues-Pousada C., Rodriguez-Belmonte E., Rodriguez-Torres A.M., Rose M., Ruzzi M., Saliola M., Sanchez-Perez M., Schaefer B., Schaefer M., Scharfe M., Schmidheini T., Schreer A., Skala J., Souciet J.-L., Steensma H.Y., Talla E., Thierry A., Vandenbol M., van der Aart Q.J.M., Van Dyck L., Vanoni M., Verhasselt P., Voet M., Volckaert G., Wambutt R., Watson M.D., Weber N., Wedler E., Wedler H., Wipfli P., Wolf K., Wright L.F., Zaccaria P., Zimmermann M., Zollner A., Kleine K.
    Nature 387:81-84(1997) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 204508 / S288c.
  3. Cited for: GENOME REANNOTATION.
    Strain: ATCC 204508 / S288c.
  4. Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
    Strain: ATCC 204508 / S288c.
  5. "Verification of 3' and 5' ends of S.cerevisiae transcripts."
    Kennedy M.C., Dietrich F.S.
    Submitted (SEP-2003) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 1-43 AND 91-147.
    Strain: ATCC 204511 / S288c / AB972.
  6. Cited for: SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS].
  7. Cited for: LEVEL OF PROTEIN EXPRESSION [LARGE SCALE ANALYSIS].
  8. Cited for: SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS].
    Strain: ATCC 76625 / YPH499.
  9. "Organization of assembly factors Cbp3p and Cbp4p and their effect on bc(1) complex assembly in Saccharomyces cerevisiae."
    Kronekova Z., Rodel G.
    Curr. Genet. 47:203-212(2005) [PubMed] [Europe PMC] [Abstract]
    Cited for: FUNCTION, INTERACTION WITH CBP3.

Entry informationi

Entry nameiCBP4_YEAST
AccessioniPrimary (citable) accession number: P37267
Secondary accession number(s): D6VUV8, Q6TQT9, Q6TQU0
Entry historyi
Integrated into UniProtKB/Swiss-Prot: October 1, 1994
Last sequence update: October 2, 2007
Last modified: October 29, 2014
This is version 112 of the entry and version 3 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Miscellaneous

Present with 704 molecules/cell in log phase SD medium.1 Publication

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. Yeast
    Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD
  3. Yeast chromosome VII
    Yeast (Saccharomyces cerevisiae) chromosome VII: entries and gene names

External Data

Dasty 3