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Protein

HTH-type transcriptional regulator DctR

Gene

dctR

Organism
Escherichia coli (strain K12)
Status
Reviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

May act as a transcriptional regulator of dctA.1 Publication

Miscellaneous

Overexpression causes filamentous biofilm formation.

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
DNA bindingi133 – 152H-T-H motifPROSITE-ProRule annotationAdd BLAST20

GO - Molecular functioni

GO - Biological processi

  • regulation of cellular carbohydrate catabolic process Source: EcoCyc
  • regulation of transcription, DNA-templated Source: UniProtKB-KW
  • transcription, DNA-templated Source: UniProtKB-KW

Keywordsi

Molecular functionDNA-binding
Biological processTranscription, Transcription regulation

Enzyme and pathway databases

BioCyciEcoCyc:EG11889-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
HTH-type transcriptional regulator DctR
Gene namesi
Name:dctR
Synonyms:yhiF
Ordered Locus Names:b3507, JW3475
OrganismiEscherichia coli (strain K12)
Taxonomic identifieri83333 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesEnterobacteriaceaeEscherichia
Proteomesi

Organism-specific databases

EcoGeneiEG11889 dctR

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001841451 – 176HTH-type transcriptional regulator DctRAdd BLAST176

Proteomic databases

PaxDbiP37195
PRIDEiP37195

Expressioni

Inductioni

By acidic conditions. Could be induced by EvgA via the induction of YdeO.2 Publications

Interactioni

Protein-protein interaction databases

BioGridi4261143, 13 interactors
DIPiDIP-12362N
IntActiP37195, 10 interactors
STRINGi316385.ECDH10B_3683

Structurei

3D structure databases

ProteinModelPortaliP37195
SMRiP37195
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini109 – 174HTH luxR-typePROSITE-ProRule annotationAdd BLAST66

Phylogenomic databases

eggNOGiCOG2771 LUCA
HOGENOMiHOG000125804
KOiK21901
OMAiCPAPEAD

Family and domain databases

CDDicd06170 LuxR_C_like, 1 hit
Gene3Di1.10.10.10, 1 hit
InterProiView protein in InterPro
IPR016032 Sig_transdc_resp-reg_C-effctor
IPR000792 Tscrpt_reg_LuxR_C
IPR036388 WH-like_DNA-bd_sf
PfamiView protein in Pfam
PF00196 GerE, 1 hit
SMARTiView protein in SMART
SM00421 HTH_LUXR, 1 hit
SUPFAMiSSF46894 SSF46894, 1 hit
PROSITEiView protein in PROSITE
PS50043 HTH_LUXR_2, 1 hit

Sequencei

Sequence statusi: Complete.

P37195-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MFLIITRDTM FFTAMKNILS KGNVVHIQNE EEIDVMLHQN AFVIIDTLMN
60 70 80 90 100
NVFHSNFLTQ IERLKPVHVI IFSPFNIKRC LGKVPVTFVP RTITIIDFVA
110 120 130 140 150
LINGSYCSVP EAAVSLSRKQ HQVLSCIANQ MTTEDILEKL KISLKTFYCH
160 170
KHNIMMILNL KRINELVRHQ HIDYLV
Length:176
Mass (Da):20,408
Last modified:October 1, 1994 - v1
Checksum:iF87354C3AB82BB83
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti163 – 176INELV…IDYLV → DQ in AAA60371 (PubMed:8022277).CuratedAdd BLAST14

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
L23635 Genomic DNA Translation: AAA60371.1
U00039 Genomic DNA Translation: AAB18483.1
U00096 Genomic DNA Translation: AAC76532.1
AP009048 Genomic DNA Translation: BAE77787.1
PIRiS47727
RefSeqiNP_417964.1, NC_000913.3
WP_000478619.1, NZ_LN832404.1

Genome annotation databases

EnsemblBacteriaiAAC76532; AAC76532; b3507
BAE77787; BAE77787; BAE77787
GeneIDi948021
KEGGiecj:JW3475
eco:b3507
PATRICifig|1411691.4.peg.3212

Entry informationi

Entry nameiDCTR_ECOLI
AccessioniPrimary (citable) accession number: P37195
Secondary accession number(s): Q2M7G9
Entry historyiIntegrated into UniProtKB/Swiss-Prot: October 1, 1994
Last sequence update: October 1, 1994
Last modified: April 25, 2018
This is version 135 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Escherichia coli
    Escherichia coli (strain K12): entries and cross-references to EcoGene

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