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Protein

Outer membrane protein slp

Gene

slp

Organism
Escherichia coli (strain K12)
Status
Reviewed-Annotation score: Annotation score: 4 out of 5-Experimental evidence at protein leveli

Functioni

The induction of slp may help to stabilize the outer membrane during carbon starvation and stationary phase.

GO - Molecular functioni

  • identical protein binding Source: IntAct
Complete GO annotation...

Enzyme and pathway databases

BioCyciEcoCyc:EG11890-MONOMER.
ECOL316407:JW3474-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Outer membrane protein slp
Gene namesi
Name:slp
Ordered Locus Names:b3506, JW3474
OrganismiEscherichia coli (strain K12)
Taxonomic identifieri83333 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeEscherichia
Proteomesi
  • UP000000318 Componenti: Chromosome
  • UP000000625 Componenti: Chromosome

Organism-specific databases

EcoGeneiEG11890. slp.

Subcellular locationi

GO - Cellular componenti

  • cell outer membrane Source: UniProtKB-SubCell
  • outer membrane Source: EcoCyc
Complete GO annotation...

Keywords - Cellular componenti

Cell outer membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Signal peptidei1 – 1818Add
BLAST
Chaini19 – 188170Outer membrane protein slpPRO_0000018187Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Lipidationi19 – 191N-palmitoyl cysteinePROSITE-ProRule annotation1 Publication
Lipidationi19 – 191S-diacylglycerol cysteinePROSITE-ProRule annotation1 Publication

Keywords - PTMi

Lipoprotein, Palmitate

Proteomic databases

PaxDbiP37194.
PRIDEiP37194.

Expressioni

Inductioni

Induced upon starvation and slowed growth. cAMP/CRP-independent.

Interactioni

Subunit structurei

Forms homooligomers.1 Publication

Binary interactionsi

WithEntry#Exp.IntActNotes
itself2EBI-907245,EBI-907245

GO - Molecular functioni

  • identical protein binding Source: IntAct

Protein-protein interaction databases

BioGridi4261141. 145 interactions.
IntActiP37194. 4 interactions.
STRINGi511145.b3506.

Structurei

3D structure databases

ProteinModelPortaliP37194.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Keywords - Domaini

Signal

Phylogenomic databases

eggNOGiENOG4105Y4Z. Bacteria.
COG3065. LUCA.
HOGENOMiHOG000277549.
InParanoidiP37194.
KOiK07285.
OMAiFIACRAG.
PhylomeDBiP37194.

Family and domain databases

InterProiIPR004658. OMP_Slp.
[Graphical view]
PfamiPF03843. Slp. 1 hit.
[Graphical view]
PIRSFiPIRSF004982. SlP. 1 hit.
TIGRFAMsiTIGR00752. slp. 1 hit.
PROSITEiPS51257. PROKAR_LIPOPROTEIN. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

P37194-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MNMTKGALIL SLSFLLAACS SIPQNIKGNN QPDIQKSFVA VHNQPGLYVG
60 70 80 90 100
QQARFGGKVI NVINGKTDTL LEISVLPLDS YAKPDIEANY QGRLLARQSG
110 120 130 140 150
FLDPVNYRNH FVTILGTIQG EQPGFINKVP YNFLEVNMQG IQVWHLREVV
160 170 180
NTTYNLWDYG YGAFWPEPGW GAPYYTNAVS QVTPELVK
Length:188
Mass (Da):20,964
Last modified:October 1, 1994 - v1
Checksum:iB2CDBC40E05ADB30
GO

Sequence cautioni

The sequence AAB18482 differs from that shown. Reason: Erroneous initiation. Translation N-terminally shortened.Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
L23635 Genomic DNA. Translation: AAA60370.1.
U00039 Genomic DNA. Translation: AAB18482.1. Different initiation.
U00096 Genomic DNA. Translation: AAC76531.2.
AP009048 Genomic DNA. Translation: BAE77788.1.
PIRiS47726.
RefSeqiNP_417963.4. NC_000913.3.
WP_001350553.1. NZ_LN832404.1.

Genome annotation databases

EnsemblBacteriaiAAC76531; AAC76531; b3506.
BAE77788; BAE77788; BAE77788.
GeneIDi948022.
KEGGiecj:JW3474.
eco:b3506.
PATRICi32122470. VBIEscCol129921_3613.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
L23635 Genomic DNA. Translation: AAA60370.1.
U00039 Genomic DNA. Translation: AAB18482.1. Different initiation.
U00096 Genomic DNA. Translation: AAC76531.2.
AP009048 Genomic DNA. Translation: BAE77788.1.
PIRiS47726.
RefSeqiNP_417963.4. NC_000913.3.
WP_001350553.1. NZ_LN832404.1.

3D structure databases

ProteinModelPortaliP37194.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi4261141. 145 interactions.
IntActiP37194. 4 interactions.
STRINGi511145.b3506.

Proteomic databases

PaxDbiP37194.
PRIDEiP37194.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAC76531; AAC76531; b3506.
BAE77788; BAE77788; BAE77788.
GeneIDi948022.
KEGGiecj:JW3474.
eco:b3506.
PATRICi32122470. VBIEscCol129921_3613.

Organism-specific databases

EchoBASEiEB1836.
EcoGeneiEG11890. slp.

Phylogenomic databases

eggNOGiENOG4105Y4Z. Bacteria.
COG3065. LUCA.
HOGENOMiHOG000277549.
InParanoidiP37194.
KOiK07285.
OMAiFIACRAG.
PhylomeDBiP37194.

Enzyme and pathway databases

BioCyciEcoCyc:EG11890-MONOMER.
ECOL316407:JW3474-MONOMER.

Miscellaneous databases

PROiP37194.

Family and domain databases

InterProiIPR004658. OMP_Slp.
[Graphical view]
PfamiPF03843. Slp. 1 hit.
[Graphical view]
PIRSFiPIRSF004982. SlP. 1 hit.
TIGRFAMsiTIGR00752. slp. 1 hit.
PROSITEiPS51257. PROKAR_LIPOPROTEIN. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiSLP_ECOLI
AccessioniPrimary (citable) accession number: P37194
Secondary accession number(s): P76709, Q2M7G8
Entry historyi
Integrated into UniProtKB/Swiss-Prot: October 1, 1994
Last sequence update: October 1, 1994
Last modified: September 7, 2016
This is version 117 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Escherichia coli
    Escherichia coli (strain K12): entries and cross-references to EcoGene

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.