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Protein

UPF0716 protein FxsA

Gene

fxsA

Organism
Escherichia coli (strain K12)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Overexpression alleviates the exclusion of phage T7 in cells harboring the F plasmid.

Enzyme and pathway databases

BioCyciEcoCyc:G7832-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
UPF0716 protein FxsA
Alternative name(s):
Suppressor of F exclusion of phage T7
Gene namesi
Name:fxsA
Synonyms:yjeG
Ordered Locus Names:b4140, JW4100
OrganismiEscherichia coli (strain K12)
Taxonomic identifieri83333 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesEnterobacteriaceaeEscherichia
Proteomesi
  • UP000000318 Componenti: Chromosome
  • UP000000625 Componenti: Chromosome

Organism-specific databases

EcoGeneiEG12382 fxsA

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Topological domaini1 – 16CytoplasmicSequence analysisAdd BLAST16
Transmembranei17 – 37HelicalSequence analysisAdd BLAST21
Topological domaini38 – 78PeriplasmicSequence analysisAdd BLAST41
Transmembranei79 – 99HelicalSequence analysisAdd BLAST21
Topological domaini100 – 158CytoplasmicSequence analysisAdd BLAST59

GO - Cellular componenti

  • integral component of membrane Source: EcoCyc
  • plasma membrane Source: EcoCyc

Keywords - Cellular componenti

Cell inner membrane, Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000873941 – 158UPF0716 protein FxsAAdd BLAST158

Proteomic databases

PaxDbiP37147
PRIDEiP37147

Interactioni

Protein-protein interaction databases

BioGridi4262196, 13 interactors
IntActiP37147, 3 interactors
STRINGi316385.ECDH10B_4333

Structurei

3D structure databases

ProteinModelPortaliP37147
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the UPF0716 (FxsA) family.Curated

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiENOG4108YH1 Bacteria
COG3030 LUCA
HOGENOMiHOG000272432
InParanoidiP37147
KOiK07113
OMAiEIGLFIQ

Family and domain databases

InterProiView protein in InterPro
IPR007313 FxsA
PANTHERiPTHR35335 PTHR35335, 1 hit
PfamiView protein in Pfam
PF04186 FxsA, 1 hit

Sequencei

Sequence statusi: Complete.

P37147-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MRWLPFIAIF LYVYIEISIF IQVAHVLGVL LTLVLVIFTS VIGMSLVRNQ
60 70 80 90 100
GFKNFVLMQQ KMAAGENPAA EMIKSVSLII AGLLLLLPGF FTDFLGLLLL
110 120 130 140 150
LPPVQKHLTV KLMPHLRFSR MPGGGFSAGT GGGNTFDGEY QRKDDERDRL

DHKDDRQD
Length:158
Mass (Da):17,692
Last modified:February 1, 1995 - v2
Checksum:iDB2338BFE146076D
GO

Sequence cautioni

The sequence AAA97039 differs from that shown. Reason: Erroneous initiation. Translation N-terminally extended.Curated
The sequence CAA27700 differs from that shown. Reason: Erroneous initiation. Translation N-terminally extended.Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U78484 Genomic DNA Translation: AAB36686.1
U14003 Genomic DNA Translation: AAA97039.1 Different initiation.
U00096 Genomic DNA Translation: AAC77100.2
AP009048 Genomic DNA Translation: BAE78142.1
X04066 Genomic DNA Translation: CAA27700.1 Different initiation.
PIRiS56368
RefSeqiNP_418564.2, NC_000913.3
WP_001267448.1, NZ_LN832404.1

Genome annotation databases

EnsemblBacteriaiAAC77100; AAC77100; b4140
BAE78142; BAE78142; BAE78142
GeneIDi948657
KEGGiecj:JW4100
eco:b4140
PATRICifig|1411691.4.peg.2560

Similar proteinsi

Entry informationi

Entry nameiFXSA_ECOLI
AccessioniPrimary (citable) accession number: P37147
Secondary accession number(s): P76797, Q2M6G4
Entry historyiIntegrated into UniProtKB/Swiss-Prot: October 1, 1994
Last sequence update: February 1, 1995
Last modified: March 28, 2018
This is version 119 of the entry and version 2 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome
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Main funding by: National Institutes of Health