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Protein

Uncharacterized fimbrial-like protein YadN

Gene

yadN

Organism
Escherichia coli (strain K12)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at transcript leveli

Functioni

Part of the yadCKLM-htrE-yadVN fimbrial operon. Could contribute to adhesion to various surfaces in specific environmental niches.1 Publication

GO - Biological processi

  • cell adhesion Source: EcoCyc
Complete GO annotation...

Enzyme and pathway databases

BioCyciEcoCyc:EG12328-MONOMER.
ECOL316407:JW0137-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Uncharacterized fimbrial-like protein YadN
Gene namesi
Name:yadN
Ordered Locus Names:b0141, JW0137
OrganismiEscherichia coli (strain K12)
Taxonomic identifieri83333 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesEnterobacteriaceaeEscherichia
Proteomesi
  • UP000000318 Componenti: Chromosome
  • UP000000625 Componenti: Chromosome

Organism-specific databases

EcoGeneiEG12328. yadN.

Subcellular locationi

GO - Cellular componenti

  • pilus Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Fimbrium

Pathology & Biotechi

Disruption phenotypei

Deletion of the operon under classical laboratory conditions does not result in any major effect on E.coli capacity to form biofilms compared with the wild-type strain.1 Publication

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 23Sequence analysisAdd BLAST23
ChainiPRO_000000925224 – 194Uncharacterized fimbrial-like protein YadNAdd BLAST171

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Disulfide bondi41 ↔ 86Sequence analysis

Keywords - PTMi

Disulfide bond

Proteomic databases

PaxDbiP37050.
PRIDEiP37050.

Expressioni

Inductioni

Repressed by H-NS.1 Publication

Interactioni

Protein-protein interaction databases

BioGridi4259737. 6 interactors.
STRINGi511145.b0141.

Structurei

3D structure databases

ProteinModelPortaliP37050.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the fimbrial protein family.Curated

Keywords - Domaini

Signal

Phylogenomic databases

HOGENOMiHOG000260127.
OMAiINNPGDI.

Family and domain databases

Gene3Di2.60.40.1090. 1 hit.
InterProiIPR008966. Adhesion_dom.
IPR000259. Adhesion_dom_fimbrial.
[Graphical view]
PfamiPF00419. Fimbrial. 1 hit.
[Graphical view]
SUPFAMiSSF49401. SSF49401. 1 hit.

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

P37050-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSKKLGFALS GLMLAMVAGT ASADMDGGQL NISGLVVDNT CETRVDGGNK
60 70 80 90 100
DGLILLQTAT VGEIDAGVLN DTVGAKAKPF SITVDCSKAN PNPGSTAKMT
110 120 130 140 150
FGSVFFGNSK GTLNNDMSIN NPSDGVNIAL HNIDGSTIKQ VQINNPGDVY
160 170 180 190
TKALDATTKS AVYDFKASYV RAVADQTATA GYVKTNTAYT ITYQ
Length:194
Mass (Da):20,118
Last modified:June 1, 1994 - v1
Checksum:i7FACE37E1447B247
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U00096 Genomic DNA. Translation: AAC73252.1.
AP009048 Genomic DNA. Translation: BAB96717.2.
PIRiE64737.
RefSeqiNP_414683.1. NC_000913.3.
WP_000038438.1. NZ_LN832404.1.

Genome annotation databases

EnsemblBacteriaiAAC73252; AAC73252; b0141.
BAB96717; BAB96717; BAB96717.
GeneIDi944841.
KEGGiecj:JW0137.
eco:b0141.
PATRICi32115389. VBIEscCol129921_0146.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U00096 Genomic DNA. Translation: AAC73252.1.
AP009048 Genomic DNA. Translation: BAB96717.2.
PIRiE64737.
RefSeqiNP_414683.1. NC_000913.3.
WP_000038438.1. NZ_LN832404.1.

3D structure databases

ProteinModelPortaliP37050.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi4259737. 6 interactors.
STRINGi511145.b0141.

Proteomic databases

PaxDbiP37050.
PRIDEiP37050.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAC73252; AAC73252; b0141.
BAB96717; BAB96717; BAB96717.
GeneIDi944841.
KEGGiecj:JW0137.
eco:b0141.
PATRICi32115389. VBIEscCol129921_0146.

Organism-specific databases

EchoBASEiEB2232.
EcoGeneiEG12328. yadN.

Phylogenomic databases

HOGENOMiHOG000260127.
OMAiINNPGDI.

Enzyme and pathway databases

BioCyciEcoCyc:EG12328-MONOMER.
ECOL316407:JW0137-MONOMER.

Miscellaneous databases

PROiP37050.

Family and domain databases

Gene3Di2.60.40.1090. 1 hit.
InterProiIPR008966. Adhesion_dom.
IPR000259. Adhesion_dom_fimbrial.
[Graphical view]
PfamiPF00419. Fimbrial. 1 hit.
[Graphical view]
SUPFAMiSSF49401. SSF49401. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiYADN_ECOLI
AccessioniPrimary (citable) accession number: P37050
Secondary accession number(s): Q8KH05
Entry historyi
Integrated into UniProtKB/Swiss-Prot: June 1, 1994
Last sequence update: June 1, 1994
Last modified: November 2, 2016
This is version 111 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Miscellaneous

The operon is cryptic under classical laboratory conditions, but is functional when constitutively expressed.1 Publication

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Escherichia coli
    Escherichia coli (strain K12): entries and cross-references to EcoGene
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.