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Protein

Carbohydrate diacid regulator

Gene

cdaR

Organism
Escherichia coli (strain K12)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Seems to regulate the expression of the operons for the enzymes involved in D-galactarate, D-glucarate and D-glycerate utilization.

GO - Molecular functioni

  • DNA binding transcription factor activity Source: EcoCyc

GO - Biological processi

  • positive regulation of transcription, DNA-templated Source: EcoCyc
  • transcription, DNA-templated Source: UniProtKB-KW

Keywordsi

Biological processTranscription, Transcription regulation

Enzyme and pathway databases

BioCyciEcoCyc:EG12335-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
Carbohydrate diacid regulator
Alternative name(s):
Sugar diacid regulator
Gene namesi
Name:cdaR
Synonyms:sdaR, yaeG
Ordered Locus Names:b0162, JW5013
OrganismiEscherichia coli (strain K12)
Taxonomic identifieri83333 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesEnterobacteriaceaeEscherichia
Proteomesi
  • UP000000318 Componenti: Chromosome
  • UP000000625 Componenti: Chromosome

Organism-specific databases

EcoGeneiEG12335 cdaR

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001659441 – 385Carbohydrate diacid regulatorAdd BLAST385

Proteomic databases

PaxDbiP37047
PRIDEiP37047

Interactioni

Protein-protein interaction databases

BioGridi4260992, 14 interactors
DIPiDIP-9258N
STRINGi316385.ECDH10B_0142

Structurei

3D structure databases

ProteinModelPortaliP37047
SMRiP37047
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the CdaR family.Curated

Phylogenomic databases

eggNOGiENOG4108IXP Bacteria
COG3835 LUCA
HOGENOMiHOG000271795
InParanoidiP37047
KOiK02647
OMAiNTRHEGA
PhylomeDBiP37047

Family and domain databases

InterProiView protein in InterPro
IPR008599 Diacid_rec
IPR025736 PucR_C-HTH_dom
PfamiView protein in Pfam
PF05651 Diacid_rec, 1 hit
PF13556 HTH_30, 1 hit

Sequencei

Sequence statusi: Complete.

P37047-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAGWHLDTKM AQDIVARTMR IIDTNINVMD ARGRIIGSGD RERIGELHEG
60 70 80 90 100
ALLVLSQGRV VDIDDAVARH LHGVRQGINL PLRLEGEIVG VIGLTGEPEN
110 120 130 140 150
LRKYGELVCM TAEMMLEQSR LMHLLAQDSR LREELVMNLI QAEENTPALT
160 170 180 190 200
EWAQRLGIDL NQPRVVAIVE VDSGQLGVDS AMAELQQLQN ALTTPERNNL
210 220 230 240 250
VAIVSLTEMV VLKPALNSFG RWDAEDHRKR VEQLITRMKE YGQLRFRVSL
260 270 280 290 300
GNYFTGPGSI ARSYRTAKTT MVVGKQRMPE SRCYFYQDLM LPVLLDSLRG
310 320 330 340 350
DWQANELARP LARLKTMDNN GLLRRTLAAW FRHNVQPLAT SKALFIHRNT
360 370 380
LEYRLNRISE LTGLDLGNFD DRLLLYVALQ LDEER
Length:385
Mass (Da):43,687
Last modified:December 15, 1998 - v2
Checksum:i5FD4EEFB33C44DBB
GO

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Natural varianti292P → S in strain: JA176; unable to grow on galactarate, glucarate and glycerate. 1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U70214 Genomic DNA Translation: AAB08592.1
U00096 Genomic DNA Translation: AAC73273.2
AP009048 Genomic DNA Translation: BAB96739.2
PIRiB64740
RefSeqiNP_414704.4, NC_000913.3
WP_000929443.1, NZ_LN832404.1

Genome annotation databases

EnsemblBacteriaiAAC73273; AAC73273; b0162
BAB96739; BAB96739; BAB96739
GeneIDi944860
KEGGiecj:JW5013
eco:b0162
PATRICifig|1411691.4.peg.2118

Similar proteinsi

Entry informationi

Entry nameiCDAR_ECOLI
AccessioniPrimary (citable) accession number: P37047
Secondary accession number(s): Q8KJQ0
Entry historyiIntegrated into UniProtKB/Swiss-Prot: June 1, 1994
Last sequence update: December 15, 1998
Last modified: March 28, 2018
This is version 132 of the entry and version 2 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

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