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Protein

Putative attaching and effacing protein homolog

Gene

eaeH

Organism
Escherichia coli (strain K12)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein uncertaini

Functioni

GO - Biological processi

Complete GO annotation...

Enzyme and pathway databases

BioCyciEcoCyc:EG12161-MONOMER.
ECOL316407:JW0291-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Putative attaching and effacing protein homolog
Gene namesi
Name:eaeH
Ordered Locus Names:b0297, JW0291
OrganismiEscherichia coli (strain K12)
Taxonomic identifieri83333 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeEscherichia
Proteomesi
  • UP000000318 Componenti: Chromosome
  • UP000000625 Componenti: Chromosome

Organism-specific databases

EcoGeneiEG12161. eaeH.

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Signal peptidei1 – 2525Sequence analysisAdd
BLAST
Chaini26 – 295270Putative attaching and effacing protein homologPRO_0000016468Add
BLAST

Proteomic databases

PRIDEiP36943.

Interactioni

Protein-protein interaction databases

BioGridi4259795. 126 interactions.
IntActiP36943. 5 interactions.
STRINGi316407.85674442.

Structurei

3D structure databases

ProteinModelPortaliP36943.
SMRiP36943. Positions 112-292.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the intimin/invasin family.Curated

Keywords - Domaini

Signal

Phylogenomic databases

HOGENOMiHOG000054880.
KOiK13735.
OMAiEAHPANG.

Family and domain databases

InterProiIPR003535. Intimin/invasin_bac.
IPR024519. Invasin_beta.
[Graphical view]
PfamiPF11924. Invasin_beta. 1 hit.
[Graphical view]
PRINTSiPR01369. INTIMIN.

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

P36943-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSHYKTGHKQ PRFRYSVLAR CVAWANISVQ VLFPLAVTFT PVMAARAQHA
60 70 80 90 100
VQPRLSMGNT TVTADNNVEK NVASFAANAG TFLSSQPDSD ATRNFITGMA
110 120 130 140 150
TAKANQEIQE WLGKYGTARV KLNVDKDFSL KDSSLEMLYP IYDTPTNMLF
160 170 180 190 200
TQGAIHRTDD RTQSNIGFGW RHFSGNDWMA GVNTFIDHDL SRSHTRIGVG
210 220 230 240 250
AEYWRDYLKL SANGYIRASG WKKSPDIEDY QERPANGWDI RAEGYLPAWP
260 270 280 290
QLGASLMYEQ YYGDEVGLFG KDKRQKDPHA ISAEVTYTPV PLTQQ
Length:295
Mass (Da):33,175
Last modified:November 1, 1997 - v2
Checksum:i93DAD573CCCB2F45
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Sequence conflicti48 – 503QHA → SMR (Ref. 4) Curated
Sequence conflicti292 – 2954LTQQ → KVLGSLSTLLACQHIHIPYQ QKFQP (Ref. 4) Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U73857 Genomic DNA. Translation: AAB18025.1.
U00096 Genomic DNA. No translation available.
AP009048 Genomic DNA. Translation: BAE76082.1.
D12594 Genomic DNA. No translation available.
PIRiA64756.
RefSeqiWP_000020224.1. NZ_LN832404.1.

Genome annotation databases

EnsemblBacteriaiBAE76082; BAE76082; BAE76082.
KEGGiecj:JW0291.
PATRICi48659800. VBIEscCol107702_0295.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U73857 Genomic DNA. Translation: AAB18025.1.
U00096 Genomic DNA. No translation available.
AP009048 Genomic DNA. Translation: BAE76082.1.
D12594 Genomic DNA. No translation available.
PIRiA64756.
RefSeqiWP_000020224.1. NZ_LN832404.1.

3D structure databases

ProteinModelPortaliP36943.
SMRiP36943. Positions 112-292.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi4259795. 126 interactions.
IntActiP36943. 5 interactions.
STRINGi316407.85674442.

Proteomic databases

PRIDEiP36943.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiBAE76082; BAE76082; BAE76082.
KEGGiecj:JW0291.
PATRICi48659800. VBIEscCol107702_0295.

Organism-specific databases

EchoBASEiEB2080.
EcoGeneiEG12161. eaeH.

Phylogenomic databases

HOGENOMiHOG000054880.
KOiK13735.
OMAiEAHPANG.

Enzyme and pathway databases

BioCyciEcoCyc:EG12161-MONOMER.
ECOL316407:JW0291-MONOMER.

Family and domain databases

InterProiIPR003535. Intimin/invasin_bac.
IPR024519. Invasin_beta.
[Graphical view]
PfamiPF11924. Invasin_beta. 1 hit.
[Graphical view]
PRINTSiPR01369. INTIMIN.
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. "Sequence of minutes 4-25 of Escherichia coli."
    Chung E., Allen E., Araujo R., Aparicio A.M., Davis K., Duncan M., Federspiel N., Hyman R., Kalman S., Komp C., Kurdi O., Lew H., Lin D., Namath A., Oefner P., Roberts D., Schramm S., Davis R.W.
    Submitted (JAN-1997) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: K12 / MG1655 / ATCC 47076.
  2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: K12 / MG1655 / ATCC 47076.
  3. "Highly accurate genome sequences of Escherichia coli K-12 strains MG1655 and W3110."
    Hayashi K., Morooka N., Yamamoto Y., Fujita K., Isono K., Choi S., Ohtsubo E., Baba T., Wanner B.L., Mori H., Horiuchi T.
    Mol. Syst. Biol. 2:E1-E5(2006) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: K12 / W3110 / ATCC 27325 / DSM 5911.
  4. Umeda M., Ohtsubo E.
    Submitted (JUL-1992) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 48-295.

Entry informationi

Entry nameiEAEH_ECOLI
AccessioniPrimary (citable) accession number: P36943
Secondary accession number(s): P77261, Q2MCC4
Entry historyi
Integrated into UniProtKB/Swiss-Prot: June 1, 1994
Last sequence update: November 1, 1997
Last modified: June 8, 2016
This is version 98 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Caution

Could be the product of a pseudogene.Curated

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Escherichia coli
    Escherichia coli (strain K12): entries and cross-references to EcoGene
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.