Reviewed,
UniProtKB/Swiss-Prot P36910 (CHIE_BETVU)
Last modified
September 22, 2009.
Version 63.
History...
Clusters with 100%,
90%,
50% identity |
Documents (2) |
Third-party data |
Customize display | text xml rdf/xml gff fasta |
Names and origin
| Protein names | Recommended name: Acidic endochitinase SE2 EC=3.2.1.14 | ||
| Gene names |
| ||
| Organism | Beta vulgaris (Sugar beet) | ||
| Taxonomic identifier | 161934 [NCBI] | ||
| Taxonomic lineage | Eukaryota › Viridiplantae › Streptophyta › Embryophyta › Tracheophyta › Spermatophyta › Magnoliophyta › eudicotyledons › core eudicotyledons › Caryophyllales › Amaranthaceae › Beta |
Protein attributes
| Sequence length | 293 AA. |
| Sequence status | Complete. |
| Sequence processing | The displayed sequence is further processed into a mature form. |
| Protein existence | Evidence at protein level. |
General annotation (Comments)
| Function | This protein functions as a defense against chitin containing fungal pathogens. This endochitinase also exhibits exochitinase activity, i.e., it is capable of hydrolyzing chito-oligosaccharides, including chitobiose. |
| Catalytic activity | Random hydrolysis of N-acetyl-beta-D-glucosaminide (1->4)-beta-linkages in chitin and chitodextrins. |
| Subcellular location | Secreted › extracellular space. Note: Intercellular fluid of leaves. |
| Tissue specificity | Accumulates in leaves during infection. |
| Induction | By fungal infection. |
| Sequence similarities | Belongs to the glycosyl hydrolase 18 family. Chitinase class II subfamily. |
Ontologies
| Keywords | |
|---|---|
| Biological process | Carbohydrate metabolism Chitin degradation Polysaccharide degradation |
| Cellular component | Secreted |
| Domain | Signal |
| Molecular function | Glycosidase Hydrolase |
| PTM | Disulfide bond |
| Technical term | Direct protein sequencing |
| Gene Ontology (GO) | |
| Biological process | chitin catabolic process Inferred from electronic annotation. Source: UniProtKB-KW |
| Cellular component | extracellular space Inferred from electronic annotation. Source: UniProtKB-SubCell |
| Molecular function | cation binding Inferred from electronic annotation. Source: InterPro chitinase activityInferred from electronic annotation. Source: EC |
| Complete GO annotation... | |
Sequence annotation (Features)
| Feature key | Position(s) | Length | Description | Graphical view | Feature identifier | ||||||
Molecule processing | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| Signal peptide | 1 – 25 | 25 | |||||||||
| Chain | 26 – 293 | 268 | Acidic endochitinase SE2 | PRO_0000011914 | |||||||
Sites | |||||||||||
| Active site | 151 | 1 | Proton donor By similarity | ||||||||
Amino acid modifications | |||||||||||
| Disulfide bond | 45 ↔ 91 | By similarity | |||||||||
| Disulfide bond | 75 ↔ 81 | By similarity | |||||||||
| Disulfide bond | 183 ↔ 212 | By similarity | |||||||||
Sequences
| ||||||||||||||||||
References
| [1] | "An acidic class III chitinase in sugar beet: induction by Cercospora beticola, characterization, and expression in transgenic tobacco plants." Nielsen K.K., Mikkelsen J.D., Kragh K.M., Bojsen K. Mol. Plant Microbe Interact. 6:495-506(1993) [PubMed: 8400378] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [MRNA], PARTIAL PROTEIN SEQUENCE. Strain: cv. Monova. Tissue: Leaf. |
Cross-references
Sequence databases | |
|---|---|
| S66038 mRNA. Translation: AAB28479.1. | |
3D structure databases | |
| HSSP | HSSP built from PDB template 2HVM based on UniProtKB P23472. |
| ModBase | Search... |
Protein family/group databases | |
| CAZy | GH18. Glycoside Hydrolase Family 18. |
Enzyme and pathway databases | |
| BRENDA | 3.2.1.14. 124. |
Family and domain databases | |
| InterPro | IPR001223. Glyco_hydro18cat. IPR001579. Glyco_hydro_18_chit_AS. IPR013781. Glyco_hydro_sg_catalytic. [Graphical view] |
| Gene3D | G3DSA:3.20.20.80. Glyco_hydro_cat. 1 hit. |
| Pfam | PF00704. Glyco_hydro_18. 1 hit. [Graphical view] |
| PROSITE | PS01095. CHITINASE_18. 1 hit. [Graphical view] |
| ProtoNet | Search... |
Entry information
| Entry name | CHIE_BETVU | ||||||||
| Accession | Primary (citable) accession number: P36910 | ||||||||
| Entry history |
| ||||||||
| Entry status | Reviewed (UniProtKB/Swiss-Prot) | ||||||||
| Annotation project | PPAP (Plant Proteome Annotation Project) | ||||||||
Relevant documents
| Glycosyl hydrolases Classification of glycosyl hydrolase families and list of entries |
| SIMILARITY comments Index of protein domains and families |

Clusters with


