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P36909

- CHIT_STRLI

UniProt

P36909 - CHIT_STRLI

Protein

Chitinase C

Gene

chiC

Organism
Streptomyces lividans
Status
Reviewed - Annotation score: 3 out of 5- Experimental evidence at transcript leveli
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    • History
      Entry version 92 (01 Oct 2014)
      Sequence version 1 (01 Jun 1994)
      Previous versions | rss
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    Functioni

    Catalytic activityi

    Random hydrolysis of N-acetyl-beta-D-glucosaminide (1->4)-beta-linkages in chitin and chitodextrins.

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Active sitei382 – 3821Proton donorPROSITE-ProRule annotation

    GO - Molecular functioni

    1. chitinase activity Source: UniProtKB-EC
    2. chitin binding Source: UniProtKB-KW
    3. polysaccharide binding Source: InterPro

    GO - Biological processi

    1. chitin catabolic process Source: UniProtKB-KW
    2. polysaccharide catabolic process Source: UniProtKB-KW

    Keywords - Molecular functioni

    Glycosidase, Hydrolase

    Keywords - Biological processi

    Carbohydrate metabolism, Chitin degradation, Polysaccharide degradation

    Keywords - Ligandi

    Chitin-binding

    Protein family/group databases

    CAZyiCBM2. Carbohydrate-Binding Module Family 2.
    GH18. Glycoside Hydrolase Family 18.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Chitinase C (EC:3.2.1.14)
    Gene namesi
    Name:chiC
    OrganismiStreptomyces lividans
    Taxonomic identifieri1916 [NCBI]
    Taxonomic lineageiBacteriaActinobacteriaActinobacteridaeActinomycetalesStreptomycineaeStreptomycetaceaeStreptomyces

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Signal peptidei1 – 3030Sequence AnalysisAdd
    BLAST
    Chaini31 – 619589Chitinase CPRO_0000011911Add
    BLAST

    Expressioni

    Inductioni

    By chitin.

    Structurei

    3D structure databases

    ProteinModelPortaliP36909.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Domains and Repeats

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Domaini31 – 134104CBM2Add
    BLAST
    Domaini144 – 22986Fibronectin type-IIIPROSITE-ProRule annotationAdd
    BLAST

    Region

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Regioni240 – 619380CatalyticAdd
    BLAST

    Sequence similaritiesi

    Contains 1 fibronectin type-III domain.PROSITE-ProRule annotation

    Keywords - Domaini

    Signal

    Family and domain databases

    Gene3Di2.60.40.10. 1 hit.
    2.60.40.290. 1 hit.
    3.10.50.10. 1 hit.
    3.20.20.80. 2 hits.
    InterProiIPR008965. Carb-bd_dom.
    IPR012291. CBD_carb-bd_dom.
    IPR018366. CBM2_CS.
    IPR001919. Cellulose-bd_dom_fam2_bac.
    IPR011583. Chitinase_II.
    IPR029070. Chitinase_insertion.
    IPR003961. Fibronectin_type3.
    IPR001223. Glyco_hydro18cat.
    IPR001579. Glyco_hydro_18_chit_AS.
    IPR013781. Glyco_hydro_catalytic_dom.
    IPR017853. Glycoside_hydrolase_SF.
    IPR013783. Ig-like_fold.
    [Graphical view]
    PfamiPF00553. CBM_2. 1 hit.
    PF00041. fn3. 1 hit.
    PF00704. Glyco_hydro_18. 1 hit.
    [Graphical view]
    SMARTiSM00637. CBD_II. 1 hit.
    SM00060. FN3. 1 hit.
    SM00636. Glyco_18. 1 hit.
    [Graphical view]
    SUPFAMiSSF49265. SSF49265. 1 hit.
    SSF49384. SSF49384. 1 hit.
    SSF51445. SSF51445. 2 hits.
    SSF54556. SSF54556. 1 hit.
    PROSITEiPS51173. CBM2. 1 hit.
    PS00561. CBM2_A. 1 hit.
    PS01095. CHITINASE_18. 1 hit.
    PS00018. EF_HAND_1. 1 hit.
    PS50853. FN3. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Sequence processingi: The displayed sequence is further processed into a mature form.

    P36909-1 [UniParc]FASTAAdd to Basket

    « Hide

    MRFRHKAAAL AATLALPLAG LVGLASPAQA ATSATATFAK TSDWGTGFGG    50
    SWTVKNTGTT SLSSWTVEWD FPTGTKVTSA WDATVTNSGD HWTAKNVGWN 100
    GTLAPGASVS FGFNGSGPGS PSNCKLNGGS CDGTSVPGDA APSAPGTPTA 150
    SNITDTSVKL SWSAATDDKG VKNYDVLRDG AKVATVTGTT YTDNGLTKGT 200
    AYSYSVKARD TADQTGPASG AVKVTTTGGG DGGNPGTGAE VKMGYFTNWG 250
    VYGRNYHVKN LVTSGSADKI THINYAFGNV QGGKCTIGDS YADYDKAYTA 300
    DQSVDGVADT WDQPLRGNFN QLRKLKAKYP NIKILYSFGG WTWSGGFPDA 350
    VKNPAAFAKS CHDLVEDPRW ADVFDGIDLD WEYPNACGLS CDETSAPNAF 400
    SSMMKAMRAE FGQDYLITAA VTADGSDGGK IDAADYGEAS KYIDWYNVMT 450
    YDFFGAWAKN GPTAPHSPLT AYDGIPQQGF NTADAMAKFK SKGVPADKLL 500
    IGIGFYGRGW TGVTQSAPGG TATGPATGTY EAGIEDYKVL KNSCPATGTI 550
    AGTAYAHCGS NWWSYDTPAT IKSKMDWAEQ QGLGGAFFWE FSGDTANGDW 600
    WRHRQRPQVT PAVRTTRRH 619
    Length:619
    Mass (Da):65,200
    Last modified:June 1, 1994 - v1
    Checksum:iA23CEE5B3C5D6F21
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    D12647 Genomic DNA. Translation: BAA02168.1.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    D12647 Genomic DNA. Translation: BAA02168.1 .

    3D structure databases

    ProteinModelPortali P36909.
    ModBasei Search...
    MobiDBi Search...

    Protein family/group databases

    CAZyi CBM2. Carbohydrate-Binding Module Family 2.
    GH18. Glycoside Hydrolase Family 18.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Family and domain databases

    Gene3Di 2.60.40.10. 1 hit.
    2.60.40.290. 1 hit.
    3.10.50.10. 1 hit.
    3.20.20.80. 2 hits.
    InterProi IPR008965. Carb-bd_dom.
    IPR012291. CBD_carb-bd_dom.
    IPR018366. CBM2_CS.
    IPR001919. Cellulose-bd_dom_fam2_bac.
    IPR011583. Chitinase_II.
    IPR029070. Chitinase_insertion.
    IPR003961. Fibronectin_type3.
    IPR001223. Glyco_hydro18cat.
    IPR001579. Glyco_hydro_18_chit_AS.
    IPR013781. Glyco_hydro_catalytic_dom.
    IPR017853. Glycoside_hydrolase_SF.
    IPR013783. Ig-like_fold.
    [Graphical view ]
    Pfami PF00553. CBM_2. 1 hit.
    PF00041. fn3. 1 hit.
    PF00704. Glyco_hydro_18. 1 hit.
    [Graphical view ]
    SMARTi SM00637. CBD_II. 1 hit.
    SM00060. FN3. 1 hit.
    SM00636. Glyco_18. 1 hit.
    [Graphical view ]
    SUPFAMi SSF49265. SSF49265. 1 hit.
    SSF49384. SSF49384. 1 hit.
    SSF51445. SSF51445. 2 hits.
    SSF54556. SSF54556. 1 hit.
    PROSITEi PS51173. CBM2. 1 hit.
    PS00561. CBM2_A. 1 hit.
    PS01095. CHITINASE_18. 1 hit.
    PS00018. EF_HAND_1. 1 hit.
    PS50853. FN3. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Multiple domain structure in a chitinase gene (chiC) of Streptomyces lividans."
      Fujii T., Miyashita K.
      J. Gen. Microbiol. 139:677-686(1993) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].

    Entry informationi

    Entry nameiCHIT_STRLI
    AccessioniPrimary (citable) accession number: P36909
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: June 1, 1994
    Last sequence update: June 1, 1994
    Last modified: October 1, 2014
    This is version 92 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Documents

    1. Glycosyl hydrolases
      Classification of glycosyl hydrolase families and list of entries
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3