Reviewed, UniProtKB/Swiss-Prot P36879 (YADG_ECOLI)

Names and origin

Protein names

Recommended name:
    Uncharacterized ABC transporter ATP-binding protein yadG

Gene names

Name:	yadG
Ordered Locus Names:	b0127, JW0123

Organism

Escherichia coli (strain K12) [Complete proteome] [HAMAP]

Taxonomic identifier

83333 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Enterobacteriales › Enterobacteriaceae › Escherichia

Protein attributes

Sequence length	308 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Evidence at protein level.

General annotation (Comments)

Sequence similarities

Belongs to the ABC transporter superfamily. Contains 1 ABC transporter domain.

Ontologies

Keywords
Biological process	Transport
Ligand	ATP-binding Nucleotide-binding
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	transport Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	ATP binding Inferred from electronic annotation. Source: UniProtKB-KW ATPase activity Inferred from electronic annotation. Source: InterPro protein binding Inferred from physical interaction. Source: IntAct
Complete GO annotation...

Binary interactions

With	Entry	#Exp.	IntAct	Notes
gadB	P69910	1	EBI-550911,EBI-549514

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 308	308	Uncharacterized ABC transporter ATP-binding protein yadG		PRO_0000093151
Regions
	Domain	5 – 236	232	ABC transporter
	Nucleotide binding	38 – 45	8	ATP Potential

Sequences

	Sequence		Length	Mass (Da)
	P36879-1 [UniParc]. Last modified June 1, 1994. Version 1. Checksum: 9EF43C2BFBFF3F47	FASTA	308	34,647
	10 20 30 40 50 60 MTIALELQQL KKTYPGGVQA LRGIDLQVEA GDFYALLGPN GAGKSTTIGI ISSLVNKTSG 70 80 90 100 110 120 RVSVFGYDLE KDVVNAKRQL GLVPQEFNFN PFETVQQIVV NQAGYYGVER KEAYIRSEKY 130 140 150 160 170 180 LKQLDLWGKR NERARMLSGG MKRRLMIARA LMHEPKLLIL DEPTAGVDIE LRRSMWGFLK 190 200 210 220 230 240 DLNDKGTTII LTTHYLEEAE MLCRNIGIIQ HGELVENTSM KALLAKLKSE TFILDLAPKS 250 260 270 280 290 300 PLPKLDGYQY RLVDTATLEV EVLREQGINS VFTQLSEQGI QVLSMRNKAN RLEELFVSLV NEKQGDRA

References

[1]	"Systematic sequencing of the Escherichia coli genome: analysis of the 2.4-4.1 min (110,917-193,643 bp) region." Fujita N., Mori H., Yura T., Ishihama A. Nucleic Acids Res. 22:1637-1639(1994) [PubMed: 8202364] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: K12 / W3110 / ATCC 27325 / DSM 5911.
[2]	"The complete genome sequence of Escherichia coli K-12." Blattner F.R., Plunkett G. III, Bloch C.A., Perna N.T., Burland V., Riley M., Collado-Vides J., Glasner J.D., Rode C.K., Mayhew G.F., Gregor J., Davis N.W., Kirkpatrick H.A., Goeden M.A., Rose D.J., Mau B., Shao Y. Science 277:1453-1474(1997) [PubMed: 9278503] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: K12 / MG1655 / ATCC 47076.
[3]	"Highly accurate genome sequences of Escherichia coli K-12 strains MG1655 and W3110." Hayashi K., Morooka N., Yamamoto Y., Fujita K., Isono K., Choi S., Ohtsubo E., Baba T., Wanner B.L., Mori H., Horiuchi T. Mol. Syst. Biol. 2:E1-E5(2006) [PubMed: 16738553] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: K12 / W3110 / ATCC 27325 / DSM 5911.

Cross-references

Sequence databases
EMBLGenBankDDBJ	U00096 Genomic DNA. Translation: AAC73238.1. AP009048 Genomic DNA. Translation: BAB96703.1.
PIR	S45204.
RefSeq	AP_000788.1. NP_414669.1.
3D structure databases
ModBase	Search...
Protein-protein interaction databases
DIP	DIP:11185N.
IntAct	P36879. 4 interactions.
STRING	P36879.
Genome annotation databases
GeneID	944833.
GenomeReviews	Gene locus JW0123 in contig AP009048_GR. Gene locus b0127 in contig U00096_GR.
KEGG	ecj:JW0123. eco:b0127.
Organism-specific databases
EchoBASE	EB2225.
EcoGene	EG12320. yadG.
CMR	Search...
Phylogenomic databases
HOGENOM	P36879.
OMA	DKQLEHA
Enzyme and pathway databases
BioCyc	EcoCyc:YADG-MON. ECOL168927:B0127-MON.
Gene expression databases
Genevestigator	P36879.
Family and domain databases
InterPro	IPR003439. ABC_transporter-like. IPR017871. ABC_transporter_CS. IPR003593. ATPase_AAA+_core. [Graphical view]
Pfam	PF00005. ABC_tran. 1 hit. [Graphical view]
SMART	SM00382. AAA. 1 hit. [Graphical view]
PROSITE	PS00211. ABC_TRANSPORTER_1. 1 hit. PS50893. ABC_TRANSPORTER_2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

YADG_ECOLI

Accession

Primary (citable) accession number: P36879

Entry history

Integrated into UniProtKB/Swiss-Prot:	June 1, 1994
Last sequence update:	June 1, 1994
Last modified:	November 24, 2009
This is version 80 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)