Reviewed, UniProtKB/Swiss-Prot P36713 (HEX8_ADE12)

Names and origin

Protein names

Recommended name:
    Hexon-associated protein
Alternative name(s):
    Protein VIII
      Short name=pVIII

Gene names

Name:

PVIII

Organism

Human adenovirus A serotype 12 (HAdV-12) (Human adenovirus 12)

Taxonomic identifier

28282 [NCBI]

Taxonomic lineage

Viruses › dsDNA viruses, no RNA stage › Adenoviridae › Mastadenovirus › Human adenovirus A

Virus host

Homo sapiens (Human) [TaxID: 9606]

Protein attributes

Sequence length	233 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is further processed into a mature form.
Protein existence	Evidence at protein level.

General annotation (Comments)

Sequence similarities

Belongs to the adenoviridae pVIII family.

Ontologies

Keywords
Molecular function	Hexon-associated protein
Technical term	Direct protein sequencing
Gene Ontology (GO)
Molecular function	hexon binding Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Propeptide	1 – 111	111	By similarity		PRO_0000036497
	Chain	112 – 233	122	Hexon-associated protein		PRO_0000036498
Sites
	Site	111 – 112	2	Cleavage; by adenovirus protease

Sequences

	Sequence		Length	Mass (Da)
	P36713-1 [UniParc]. Last modified June 1, 1994. Version 1. Checksum: 63111557E3D83CAF	FASTA	233	25,254
	10 20 30 40 50 60 MSKDIPTPYM WSFQPQMGLA AGAAQDYSSK MNWLSAGPHM ISRVNGVRAR RNQILLEQAA 70 80 90 100 110 120 LTATPRNQLN PPSWPAALIY QENPPPTTVL LPRDAQAEVH MTNAGAQLAG GARHSFRYKG 130 140 150 160 170 180 RTEPYPSPAI KRVLIRGKGI QLNDEVTSPL GVRPDGVFQL GGSGRSSFTA RQAYLTLQSS 190 200 210 220 230 SSAPRSGGIG TLQFVEEFTP SVYFNPFSGS PGHYPDAFIP NFDAVSESVD GYD

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Nucleotide sequence of human adenovirus type 12 DNA: comparative functional analysis." Sprengel J., Schmitz B., Heuss-Neitzel D., Zock C., Doerfler W. J. Virol. 68:379-389(1994) [PubMed: 8254750] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
[2]	"Human adenovirus serotype 12 virion precursors pMu and pVI are cleaved at amino-terminal and carboxy-terminal sites that conform to the adenovirus 2 endoproteinase cleavage consensus sequence." Freimuth P., Anderson C.W. Virology 193:348-355(1993) [PubMed: 8438575] [Abstract] Cited for: PROTEIN SEQUENCE OF 139-156 AND 165-178. Strain: Huie.

Cross-references

Sequence databases
EMBLGenBankDDBJ	X73487 Genomic DNA. Translation: CAA51895.1.
PIR	S33946.
RefSeq	NP_040928.1.
3D structure databases
ModBase	Search...
Genome annotation databases
GeneID	1460842.
Family and domain databases
InterPro	IPR000646. Adeno_PVIII. [Graphical view]
Pfam	PF01310. Adeno_PVIII. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

HEX8_ADE12

Accession

Primary (citable) accession number: P36713

Entry history

Integrated into UniProtKB/Swiss-Prot:	June 1, 1994
Last sequence update:	June 1, 1994
Last modified:	July 28, 2009
This is version 37 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

Virus (Virus annotation project)