P36710 (E434_ADE12) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names	Recommended name: Early E4 34 kDa protein
Organism	Human adenovirus A serotype 12 (HAdV-12) (Human adenovirus 12)
Taxonomic identifier	28282 [NCBI]
Taxonomic lineage	Viruses › dsDNA viruses, no RNA stage › Adenoviridae › Mastadenovirus › Human adenovirus A
Virus host	Homo sapiens (Human) [TaxID: 9606]

Protein attributes

Sequence length	291 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Sequence similarities

Belongs to the adenoviridae E4 30 to 34 kDa protein family.

Ontologies

Keywords
Developmental stage	Early protein
Gene Ontology (GO)
None. [Check GOA]

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 291	291	Early E4 34 kDa protein		PRO_0000221778
Experimental info
	Sequence conflict	228 – 229	2	CA → WP in CAB57854. Ref.2

Sequences

	Sequence		Length	Mass (Da)
	P36710 [UniParc]. Last modified June 1, 1994. Version 1. Checksum: CD1A07D37FBB5E96	FASTA	291	34,383
	10 20 30 40 50 60 MQRDRRYRYR LAPYNKYQLP PCEEQSKATL STSENSLWPE CNSLTLHNVS EVRGIPSCVG 70 80 90 100 110 120 FTVLQEWPIP WDMILTDYEM FILKKYMSVC MCCATINVEV TQLLHGHERW LIHCHCQRPG 130 140 150 160 170 180 SLQCMSAGML LGRWFKMAVY GALINKRCFW YREVVNHLMP KEVMYVGSTF VRGRHLIYFK 190 200 210 220 230 240 IMYDGHAWLA LEKVSFGWSA FNYGILNNML VLCCDYCKDL SEIRMRCCAR RTRLLMLKVV 250 260 270 280 290 QVIAENTVRP LKHSRHERYR QQLLKGLIMH HRAILFGDYN QRENPWAADG H

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Nucleotide sequence of human adenovirus type 12 DNA: comparative functional analysis." Sprengel J., Schmitz B., Heuss-Neitzel D., Zock C., Doerfler W. J. Virol. 68:379-389(1994) [PubMed: 8254750] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
[2]	"Nucleotide sequence of the right 10% of adenovirus type 12 DNA encoding the entire region E4." Hogenkamp T., Esche H. Nucleic Acids Res. 18:3065-3066(1990) [PubMed: 2349112] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	X73487 Genomic DNA. Translation: CAA51901.1. X51800 Genomic DNA. Translation: CAB57854.1.
PIR	S10867.
RefSeq	NP_040934.1. NC_001460.1.
3D structure databases
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	1460865.
Phylogenomic databases
ProtClustDB	CLSP2513892.
Family and domain databases
InterPro	IPR007615. Adenovirus_E4. [Graphical view]
Pfam	PF04528. Adeno_E4_34. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

E434_ADE12

Accession

Primary (citable) accession number: P36710

Entry history

Integrated into UniProtKB/Swiss-Prot:	June 1, 1994
Last sequence update:	June 1, 1994
Last modified:	March 8, 2011
This is version 39 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Viral Protein Annotation Program