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Protein

Putative type II secretion system protein M

Gene

gspM

Organism
Escherichia coli (strain K12)
Status
Reviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins.Curated

Miscellaneous

Part of a cryptic operon that encodes proteins involved in type II secretion machinery in other organisms, but is not expressed in strain K12.

GO - Biological processi

Keywordsi

Biological processProtein transport, Transport

Enzyme and pathway databases

BioCyciEcoCyc:EG12173-MONOMER
MetaCyc:EG12173-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
Putative type II secretion system protein M
Short name:
T2SS protein M
Alternative name(s):
Putative general secretion pathway protein M
Transport protein PshM
Gene namesi
Name:gspM
Synonyms:hopZ, pshM
Ordered Locus Names:b3334, JW5704
OrganismiEscherichia coli (strain K12)
Taxonomic identifieri83333 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesEnterobacteriaceaeEscherichia
Proteomesi
  • UP000000318 Componenti: Chromosome
  • UP000000625 Componenti: Chromosome

Organism-specific databases

EcoGeneiEG12173 gspM

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Topological domaini1 – 16CytoplasmicSequence analysisAdd BLAST16
Transmembranei17 – 37HelicalSequence analysisAdd BLAST21
Topological domaini38 – 153PeriplasmicSequence analysisAdd BLAST116

GO - Cellular componenti

Keywords - Cellular componenti

Cell inner membrane, Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002073231 – 153Putative type II secretion system protein MAdd BLAST153

Proteomic databases

PaxDbiP36678
PRIDEiP36678

Expressioni

Inductioni

Silenced by the DNA-binding protein H-NS under standard growth conditions.1 Publication

Interactioni

Protein-protein interaction databases

BioGridi4262464, 145 interactors
STRINGi316385.ECDH10B_3509

Structurei

3D structure databases

ProteinModelPortaliP36678
SMRiP36678
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the GSP M family.Curated

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiENOG410ZA7S LUCA
HOGENOMiHOG000125397
KOiK02462
OMAiKCHERCN

Family and domain databases

InterProiView protein in InterPro
IPR007690 T2SS_M
IPR023229 T2SS_M_periplasmic_sf
PfamiView protein in Pfam
PF04612 T2SSM, 1 hit
SUPFAMiSSF103054 SSF103054, 1 hit

Sequencei

Sequence statusi: Complete.

P36678-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MIKSWWAEKS TSEKQIVAAL AVLSLGVFCW LGVIKPIDTY IAEHQSHAQK
60 70 80 90 100
IKKDIKWMQD QASTHGLLGH PALTQPIKNI LLEEAKRENL AITLENGPDN
110 120 130 140 150
TLTIHPVTAP LENVSRWLTT AQVTYGIVIE DLQFTLAGNE EITLRHLSFR

EQQ
Length:153
Mass (Da):17,234
Last modified:December 15, 1998 - v2
Checksum:i8BF3991FB160383C
GO

Sequence cautioni

The sequence AAA58131 differs from that shown. Reason: Erroneous initiation. Translation N-terminally shortened.Curated
The sequence AAC36927 differs from that shown. Reason: Erroneous initiation. Translation N-terminally shortened.Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
L28106 Genomic DNA Translation: AAC36927.1 Different initiation.
U18997 Genomic DNA Translation: AAA58131.1 Different initiation.
U00096 Genomic DNA Translation: AAC76359.2
AP009048 Genomic DNA Translation: BAE77957.1
PIRiA65127
RefSeqiNP_417793.2, NC_000913.3
WP_001295161.1, NZ_LN832404.1

Genome annotation databases

EnsemblBacteriaiAAC76359; AAC76359; b3334
BAE77957; BAE77957; BAE77957
GeneIDi947841
KEGGiecj:JW5704
eco:b3334
PATRICifig|1411691.4.peg.3397

Similar proteinsi

Entry informationi

Entry nameiGSPM_ECOLI
AccessioniPrimary (citable) accession number: P36678
Secondary accession number(s): Q2M6Z9
Entry historyiIntegrated into UniProtKB/Swiss-Prot: June 1, 1994
Last sequence update: December 15, 1998
Last modified: March 28, 2018
This is version 117 of the entry and version 2 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Escherichia coli
    Escherichia coli (strain K12): entries and cross-references to EcoGene
  2. SIMILARITY comments
    Index of protein domains and families

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