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Protein

Protein transport protein HofB homolog

Gene

hofB

Organism
Escherichia coli (strain K12)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi222 – 2298ATPSequence analysis

GO - Molecular functioni

GO - Biological processi

  • plasmid maintenance Source: EcoCyc
  • transport Source: UniProtKB-KW
Complete GO annotation...

Keywords - Biological processi

Transport

Keywords - Ligandi

ATP-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciEcoCyc:EG12106-MONOMER.
ECOL316407:JW0103-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Protein transport protein HofB homolog
Gene namesi
Name:hofB
Synonyms:hopB
Ordered Locus Names:b0107, JW0103
OrganismiEscherichia coli (strain K12)
Taxonomic identifieri83333 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeEscherichia
Proteomesi
  • UP000000318 Componenti: Chromosome
  • UP000000625 Componenti: Chromosome

Organism-specific databases

EcoGeneiEG12106. hofB.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 461461Protein transport protein HofB homologPRO_0000207305Add
BLAST

Proteomic databases

PaxDbiP36645.
PRIDEiP36645.

Interactioni

Protein-protein interaction databases

BioGridi4261684. 8 interactions.
DIPiDIP-9919N.
IntActiP36645. 5 interactions.
STRINGi511145.b0107.

Structurei

3D structure databases

ProteinModelPortaliP36645.
SMRiP36645. Positions 80-453.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the GSP E family.Curated

Phylogenomic databases

eggNOGiENOG4107QHF. Bacteria.
COG2804. LUCA.
HOGENOMiHOG000008427.
InParanoidiP36645.
KOiK02504.
OMAiLQTWRAP.
OrthoDBiEOG63Z76W.
PhylomeDBiP36645.

Family and domain databases

Gene3Di3.40.50.300. 1 hit.
InterProiIPR007831. GSPII_E_N.
IPR027417. P-loop_NTPase.
IPR001482. T2SS_protein-E.
[Graphical view]
PfamiPF00437. T2SSE. 1 hit.
PF05157. T2SSE_N. 1 hit.
[Graphical view]
SUPFAMiSSF52540. SSF52540. 1 hit.
PROSITEiPS00662. T2SP_E. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P36645-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MNIPQLTALC LRYHGVLLDA SEEVVHVAVV DAPSHELLDA LHFATTKRIE
60 70 80 90 100
ITCWTRQQME GHASRTQQTL PVAVQEKHQP KAELLTRTLQ SALEQRASDI
110 120 130 140 150
HIEPADNAYR IRLRIDGVLH PLPDVSPDAG VALTARLKVL GNLDIAEHRL
160 170 180 190 200
PQDGQFTVEL AGNAVSFRIA TLPCRGGEKV VLRLLQQVGQ ALDVNTLGMQ
210 220 230 240 250
PLQLADFAHA LQQPQGLVLV TGPTGSGKTV TLYSALQKLN TADINICSVE
260 270 280 290 300
DPVEIPIAGL NQTQIHPRAG LTFQGVLRAL LRQDPDVIMI GEIRDGETAE
310 320 330 340 350
IAIKAAQTGH LVLSTLHTNS TCETLVRLQQ MGVARWMLSS ALTLVIAQRL
360 370 380 390 400
VRKLCPHCRR QQGEPIHIPD NVWPSPLPHW QAPGCVHCYH GFYGRTALFE
410 420 430 440 450
VLPITPVIRQ LISANTDVES LETHARQAGM RTLFENGCLA VEQGLTTFEE
460
LIRVLGMPHG E
Length:461
Mass (Da):50,615
Last modified:November 1, 1997 - v3
Checksum:i3E3A72AB05760255
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Sequence conflicti8 – 92AL → EM in AAC36924 (PubMed:7959070).Curated
Sequence conflicti35 – 351H → L in AAC36924 (PubMed:7959070).Curated
Sequence conflicti457 – 4615MPHGE → DAAWQ in AAC36924 (PubMed:7959070).Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
L28105 Genomic DNA. Translation: AAC36924.1.
U00096 Genomic DNA. Translation: AAC73218.1.
AP009048 Genomic DNA. Translation: BAB96676.2.
L20834 Genomic DNA. No translation available.
PIRiC64733.
RefSeqiNP_414649.1. NC_000913.3.
WP_001025145.1. NZ_LN832404.1.

Genome annotation databases

EnsemblBacteriaiAAC73218; AAC73218; b0107.
BAB96676; BAB96676; BAB96676.
GeneIDi947481.
KEGGiecj:JW0103.
eco:b0107.
PATRICi32115315. VBIEscCol129921_0109.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
L28105 Genomic DNA. Translation: AAC36924.1.
U00096 Genomic DNA. Translation: AAC73218.1.
AP009048 Genomic DNA. Translation: BAB96676.2.
L20834 Genomic DNA. No translation available.
PIRiC64733.
RefSeqiNP_414649.1. NC_000913.3.
WP_001025145.1. NZ_LN832404.1.

3D structure databases

ProteinModelPortaliP36645.
SMRiP36645. Positions 80-453.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi4261684. 8 interactions.
DIPiDIP-9919N.
IntActiP36645. 5 interactions.
STRINGi511145.b0107.

Proteomic databases

PaxDbiP36645.
PRIDEiP36645.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAC73218; AAC73218; b0107.
BAB96676; BAB96676; BAB96676.
GeneIDi947481.
KEGGiecj:JW0103.
eco:b0107.
PATRICi32115315. VBIEscCol129921_0109.

Organism-specific databases

EchoBASEiEB2030.
EcoGeneiEG12106. hofB.

Phylogenomic databases

eggNOGiENOG4107QHF. Bacteria.
COG2804. LUCA.
HOGENOMiHOG000008427.
InParanoidiP36645.
KOiK02504.
OMAiLQTWRAP.
OrthoDBiEOG63Z76W.
PhylomeDBiP36645.

Enzyme and pathway databases

BioCyciEcoCyc:EG12106-MONOMER.
ECOL316407:JW0103-MONOMER.

Miscellaneous databases

PROiP36645.

Family and domain databases

Gene3Di3.40.50.300. 1 hit.
InterProiIPR007831. GSPII_E_N.
IPR027417. P-loop_NTPase.
IPR001482. T2SS_protein-E.
[Graphical view]
PfamiPF00437. T2SSE. 1 hit.
PF05157. T2SSE_N. 1 hit.
[Graphical view]
SUPFAMiSSF52540. SSF52540. 1 hit.
PROSITEiPS00662. T2SP_E. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. "Escherichia coli contains a set of genes homologous to those involved in protein secretion, DNA uptake and the assembly of type-4 fimbriae in other bacteria."
    Whitchurch C.B., Mattick J.S.
    Gene 150:9-15(1994) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
    Strain: K12.
  2. "Systematic sequencing of the Escherichia coli genome: analysis of the 2.4-4.1 min (110,917-193,643 bp) region."
    Fujita N., Mori H., Yura T., Ishihama A.
    Nucleic Acids Res. 22:1637-1639(1994) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: K12 / W3110 / ATCC 27325 / DSM 5911.
  3. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: K12 / MG1655 / ATCC 47076.
  4. "Highly accurate genome sequences of Escherichia coli K-12 strains MG1655 and W3110."
    Hayashi K., Morooka N., Yamamoto Y., Fujita K., Isono K., Choi S., Ohtsubo E., Baba T., Wanner B.L., Mori H., Horiuchi T.
    Mol. Syst. Biol. 2:E1-E5(2006) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA], SEQUENCE REVISION.
    Strain: K12 / W3110 / ATCC 27325 / DSM 5911.
  5. Bhatia R.S.
    Submitted (NOV-1993) to the EMBL/GenBank/DDBJ databases
    Cited for: PRELIMINARY NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 1-283.
    Strain: K12.
  6. Rudd K.R.
    Unpublished observations (JAN-1994)
    Cited for: IDENTIFICATION.

Entry informationi

Entry nameiHOFB_ECOLI
AccessioniPrimary (citable) accession number: P36645
Secondary accession number(s): P75649, Q47022
Entry historyi
Integrated into UniProtKB/Swiss-Prot: June 1, 1994
Last sequence update: November 1, 1997
Last modified: May 11, 2016
This is version 115 of the entry and version 3 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Escherichia coli
    Escherichia coli (strain K12): entries and cross-references to EcoGene
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.