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Protein

Arrestin-C

Gene

Arr3

Organism
Rattus norvegicus (Rat)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at transcript leveli

Functioni

May play a role in an as yet undefined retina-specific signal transduction. Could binds to photoactivated-phosphorylated red/green opsins.

GO - Molecular functioni

  • protein domain specific binding Source: RGD

GO - Biological processi

  • negative regulation of signal transduction Source: RGD
  • signal transduction Source: InterPro
  • visual perception Source: RGD
Complete GO annotation...

Keywords - Biological processi

Sensory transduction, Vision

Names & Taxonomyi

Protein namesi
Recommended name:
Arrestin-C
Alternative name(s):
Cone arrestin
Short name:
cArr
Retinal cone arrestin-3
Gene namesi
Name:Arr3
Synonyms:Car
OrganismiRattus norvegicus (Rat)
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeRattus
Proteomesi
  • UP000002494 Componenti: Unplaced

Organism-specific databases

RGDi621385. Arr3.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini‹1 – 92›92Arrestin-CPRO_0000205205Add
BLAST

Proteomic databases

PaxDbiP36576.

Expressioni

Tissue specificityi

Retina and pineal gland.

Interactioni

Subunit structurei

Interacts with CXCR4; the interaction is dependent on the C-terminal phosphorylation of CXCR4 and modulates the calcium ion mobilization activity of CXCR4.By similarity

GO - Molecular functioni

  • protein domain specific binding Source: RGD

Protein-protein interaction databases

STRINGi10116.ENSRNOP00000003946.

Structurei

3D structure databases

ProteinModelPortaliP36576.
SMRiP36576. Positions 1-86.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the arrestin family.Curated

Phylogenomic databases

eggNOGiKOG3865. Eukaryota.
ENOG410XR0F. LUCA.
HOGENOMiHOG000231319.
InParanoidiP36576.

Family and domain databases

Gene3Di2.60.40.640. 1 hit.
InterProiIPR033042. ARR3.
IPR000698. Arrestin.
IPR014752. Arrestin_C.
IPR014756. Ig_E-set.
[Graphical view]
PANTHERiPTHR11792. PTHR11792. 1 hit.
PTHR11792:SF19. PTHR11792:SF19. 1 hit.
SUPFAMiSSF81296. SSF81296. 1 hit.

Sequencei

Sequence statusi: Fragment.

P36576-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
LKHEDTNLAS STILRPGMNK ELLGILVSYK VKVNLMVSYG GILGGLPASD
60 70 80 90
VGVELPLILI HPKPPHGERA VATSSEDIVV EEFTQQNSQT QS
Length:92
Mass (Da):9,878
Last modified:June 1, 1994 - v1
Checksum:i88F0C948643C83B9
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Non-terminal residuei1 – 11

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U03628 mRNA. Translation: AAA17552.1.
PIRiI70113.
UniGeneiRn.20297.

Genome annotation databases

UCSCiRGD:621385. rat.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U03628 mRNA. Translation: AAA17552.1.
PIRiI70113.
UniGeneiRn.20297.

3D structure databases

ProteinModelPortaliP36576.
SMRiP36576. Positions 1-86.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10116.ENSRNOP00000003946.

Proteomic databases

PaxDbiP36576.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

UCSCiRGD:621385. rat.

Organism-specific databases

RGDi621385. Arr3.

Phylogenomic databases

eggNOGiKOG3865. Eukaryota.
ENOG410XR0F. LUCA.
HOGENOMiHOG000231319.
InParanoidiP36576.

Family and domain databases

Gene3Di2.60.40.640. 1 hit.
InterProiIPR033042. ARR3.
IPR000698. Arrestin.
IPR014752. Arrestin_C.
IPR014756. Ig_E-set.
[Graphical view]
PANTHERiPTHR11792. PTHR11792. 1 hit.
PTHR11792:SF19. PTHR11792:SF19. 1 hit.
SUPFAMiSSF81296. SSF81296. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiARRC_RAT
AccessioniPrimary (citable) accession number: P36576
Entry historyi
Integrated into UniProtKB/Swiss-Prot: June 1, 1994
Last sequence update: June 1, 1994
Last modified: April 13, 2016
This is version 89 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.