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Protein

Acid shock protein

Gene

asr

Organism
Escherichia coli (strain K12)
Status
Reviewed-Annotation score: Annotation score: 4 out of 5-Experimental evidence at protein leveli

Functioni

Required for growth and/or survival at acidic conditions (pH 4.5). Needed for the adaptation process at pH 4.5 that enables cells to survive at extremely low pH (pH 2.0).1 Publication

GO - Biological processi

  • response to zinc ion Source: EcoCyc

Enzyme and pathway databases

BioCyciEcoCyc:G6855-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Acid shock protein
Gene namesi
Name:asr
Ordered Locus Names:b1597, JW5826
OrganismiEscherichia coli (strain K12)
Taxonomic identifieri83333 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesEnterobacteriaceaeEscherichia
Proteomesi
  • UP000000318 Componenti: Chromosome
  • UP000000625 Componenti: Chromosome

Organism-specific databases

EcoGeneiEG12149. asr.

Subcellular locationi

GO - Cellular componenti

  • periplasmic space Source: EcoCyc

Keywords - Cellular componenti

Periplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 211 PublicationAdd BLAST21
PropeptideiPRO_000026950322 – 581 PublicationAdd BLAST37
ChainiPRO_000000240259 – 102Acid shock proteinAdd BLAST44

Post-translational modificationi

Proteolytic processing gives rise to the active protein.1 Publication

Proteomic databases

PaxDbiP36560.
PRIDEiP36560.

Expressioni

Inductioni

By high environmental acidity.

Interactioni

Protein-protein interaction databases

BioGridi4259122. 16 interactors.
DIPiDIP-9183N.
IntActiP36560. 5 interactors.
MINTiMINT-1320044.
STRINGi511145.b1597.

Structurei

3D structure databases

ProteinModelPortaliP36560.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the Asr family.Curated

Keywords - Domaini

Signal

Phylogenomic databases

OMAiTTHVKKH.

Family and domain databases

HAMAPiMF_00546. Asr. 1 hit.
InterProiView protein in InterPro
IPR023497. Acid_shock.

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

P36560-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKKVLALVVA AAMGLSSAAF AAETTTTPAP TATTTKAAPA KTTHHKKQHK
60 70 80 90 100
AAPAQKAQAA KKHHKNTKAE QKAPEQKAQA AKKHAKKHSH QQPAKPAAQP

AA
Length:102
Mass (Da):10,591
Last modified:April 27, 2001 - v3
Checksum:i3E92AAE86D3975AF
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF405541 Genomic DNA. Translation: AAA23500.2.
U00096 Genomic DNA. Translation: AAC74669.2.
AP009048 Genomic DNA. Translation: BAA15331.2.
PIRiG64915.
RefSeqiNP_416114.2. NC_000913.3.

Genome annotation databases

EnsemblBacteriaiAAC74669; AAC74669; b1597.
BAA15331; BAA15331; BAA15331.
GeneIDi945103.
KEGGiecj:JW5826.
eco:b1597.
PATRICi32118496. VBIEscCol129921_1668.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF405541 Genomic DNA. Translation: AAA23500.2.
U00096 Genomic DNA. Translation: AAC74669.2.
AP009048 Genomic DNA. Translation: BAA15331.2.
PIRiG64915.
RefSeqiNP_416114.2. NC_000913.3.

3D structure databases

ProteinModelPortaliP36560.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi4259122. 16 interactors.
DIPiDIP-9183N.
IntActiP36560. 5 interactors.
MINTiMINT-1320044.
STRINGi511145.b1597.

Proteomic databases

PaxDbiP36560.
PRIDEiP36560.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAC74669; AAC74669; b1597.
BAA15331; BAA15331; BAA15331.
GeneIDi945103.
KEGGiecj:JW5826.
eco:b1597.
PATRICi32118496. VBIEscCol129921_1668.

Organism-specific databases

EchoBASEiEB2069.
EcoGeneiEG12149. asr.

Phylogenomic databases

OMAiTTHVKKH.

Enzyme and pathway databases

BioCyciEcoCyc:G6855-MONOMER.

Miscellaneous databases

PROiPR:P36560.

Family and domain databases

HAMAPiMF_00546. Asr. 1 hit.
InterProiView protein in InterPro
IPR023497. Acid_shock.
ProtoNetiSearch...

Entry informationi

Entry nameiASR_ECOLI
AccessioniPrimary (citable) accession number: P36560
Secondary accession number(s): P77267
Entry historyiIntegrated into UniProtKB/Swiss-Prot: June 1, 1994
Last sequence update: April 27, 2001
Last modified: February 15, 2017
This is version 117 of the entry and version 3 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Direct protein sequencing, Reference proteome

Documents

  1. Escherichia coli
    Escherichia coli (strain K12): entries and cross-references to EcoGene
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.