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P36550

- CWLL_BACLI

UniProt

P36550 - CWLL_BACLI

Protein

N-acetylmuramoyl-L-alanine amidase CwlL

Gene

cwlL

Organism
Bacillus licheniformis
Status
Reviewed - Annotation score: 3 out of 5- Protein inferred from homologyi
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    • History
      Entry version 67 (01 Oct 2014)
      Sequence version 1 (01 Jun 1994)
      Previous versions | rss
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    Functioni

    Catalytic activityi

    Hydrolyzes the link between N-acetylmuramoyl residues and L-amino acid residues in certain cell-wall glycopeptides.

    GO - Molecular functioni

    1. N-acetylmuramoyl-L-alanine amidase activity Source: UniProtKB-EC

    GO - Biological processi

    1. peptidoglycan catabolic process Source: InterPro

    Keywords - Molecular functioni

    Hydrolase

    Keywords - Biological processi

    Cell wall biogenesis/degradation

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    N-acetylmuramoyl-L-alanine amidase CwlL (EC:3.5.1.28)
    Alternative name(s):
    Autolysin
    Cell wall hydrolase
    Gene namesi
    Name:cwlL
    OrganismiBacillus licheniformis
    Taxonomic identifieri1402 [NCBI]
    Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesBacillaceaeBacillus

    Subcellular locationi

    Secreted Curated

    GO - Cellular componenti

    1. extracellular region Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Secreted

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Signal peptidei1 – 3939By similarityAdd
    BLAST
    Chaini40 – 360321N-acetylmuramoyl-L-alanine amidase CwlLPRO_0000006455Add
    BLAST

    Structurei

    3D structure databases

    ProteinModelPortaliP36550.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Domains and Repeats

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Repeati166 – 191261-1Add
    BLAST
    Repeati196 – 259642-1Add
    BLAST
    Repeati265 – 289251-2Add
    BLAST
    Repeati291 – 355652-2Add
    BLAST

    Region

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Regioni166 – 2891242 X approximate repeatsAdd
    BLAST
    Regioni196 – 3551602 X approximate repeatsAdd
    BLAST

    Sequence similaritiesi

    Keywords - Domaini

    Repeat, Signal

    Family and domain databases

    Gene3Di1.10.101.10. 2 hits.
    3.40.80.10. 1 hit.
    InterProiIPR002502. Amidase_domain.
    IPR002477. Peptidoglycan-bd-like.
    [Graphical view]
    PfamiPF01510. Amidase_2. 1 hit.
    PF01471. PG_binding_1. 2 hits.
    [Graphical view]
    SMARTiSM00644. Ami_2. 1 hit.
    [Graphical view]
    SUPFAMiSSF47090. SSF47090. 2 hits.
    SSF55846. SSF55846. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    Sequence processingi: The displayed sequence is further processed into a mature form.

    P36550-1 [UniParc]FASTAAdd to Basket

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    MVKVVKNFVK VNQYTRPGLK LAGVKGIVMH YTATPGASAL NERDYFNGTC    50
    IAIKRKASSA HYFVDRKEAQ HIIPENEVAY HAHDKNRCYV SFLKPNANTK 100
    SISVEMCVEK DGMIHSETVQ NAAELVADLC KRYGLSTNKI VRHYDVTNKI 150
    CPAPWVSDSS QLTTFRKKVD SLLGNKTVSK TTSSTSQSSK STGTILKKGA 200
    SGSQVKALQK RLIAAGFSLP KYGADGSYEN ETVQAVKALQ KKAGIAVDGI 250
    YGPATEKALA AIGAKKKKPS SNGKKTSYPL PSGIYKVKSP LMKGTGVRQI 300
    QEALAALYFY PDKGAKNNGI DGYYGPKTAN AVKRFQLMHG LSADGIYGSD 350
    TKAKLKTLLK 360
    Length:360
    Mass (Da):38,996
    Last modified:June 1, 1994 - v1
    Checksum:i37C07B4A084364DA
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    D13377 Genomic DNA. Translation: BAA02647.1.
    PIRiS39916.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    D13377 Genomic DNA. Translation: BAA02647.1 .
    PIRi S39916.

    3D structure databases

    ProteinModelPortali P36550.
    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Family and domain databases

    Gene3Di 1.10.101.10. 2 hits.
    3.40.80.10. 1 hit.
    InterProi IPR002502. Amidase_domain.
    IPR002477. Peptidoglycan-bd-like.
    [Graphical view ]
    Pfami PF01510. Amidase_2. 1 hit.
    PF01471. PG_binding_1. 2 hits.
    [Graphical view ]
    SMARTi SM00644. Ami_2. 1 hit.
    [Graphical view ]
    SUPFAMi SSF47090. SSF47090. 2 hits.
    SSF55846. SSF55846. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. "Molecular cloning, sequence analysis, and characterization of a new cell wall hydrolase, CwlL, of Bacillus licheniformis."
      Oda Y., Nakayama R., Kuroda A., Sekiguchi J.
      Mol. Gen. Genet. 241:380-388(1993) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
      Strain: FD0120.

    Entry informationi

    Entry nameiCWLL_BACLI
    AccessioniPrimary (citable) accession number: P36550
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: June 1, 1994
    Last sequence update: June 1, 1994
    Last modified: October 1, 2014
    This is version 67 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Documents

    1. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3