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Protein

HTH-type transcriptional regulator eutR

Gene

eutR

Organism
Escherichia coli (strain K12)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Activates the transcription of the eut operon. Also positively regulates its own transcription. Probably binds ethanolamine and vitamin B12 as effectors (By similarity).By similarity

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
DNA bindingi259 – 278H-T-H motifPROSITE-ProRule annotationAdd BLAST20

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionActivator, DNA-binding
Biological processTranscription, Transcription regulation

Enzyme and pathway databases

BioCyciEcoCyc:EG12190-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
HTH-type transcriptional regulator eutR
Alternative name(s):
Ethanolamine operon regulatory protein
Gene namesi
Name:eutR
Synonyms:yfeG
Ordered Locus Names:b2437, JW2430
OrganismiEscherichia coli (strain K12)
Taxonomic identifieri83333 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesEnterobacteriaceaeEscherichia
Proteomesi

Organism-specific databases

EcoGeneiEG12190 eutR

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001945091 – 350HTH-type transcriptional regulator eutRAdd BLAST350

Proteomic databases

PaxDbiP36547
PRIDEiP36547

Interactioni

Protein-protein interaction databases

IntActiP36547, 3 interactors
STRINGi316385.ECDH10B_2602

Structurei

3D structure databases

ProteinModelPortaliP36547
SMRiP36547
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Phylogenomic databases

eggNOGiENOG4108K3Z Bacteria
ENOG410ZX7Q LUCA
HOGENOMiHOG000117033
KOiK04033
OMAiFLHHPER
PhylomeDBiP36547

Family and domain databases

InterProiView protein in InterPro
IPR009057 Homeobox-like_sf
IPR018060 HTH_AraC
IPR018062 HTH_AraC-typ_CS
PfamiView protein in Pfam
PF12833 HTH_18, 1 hit
SMARTiView protein in SMART
SM00342 HTH_ARAC, 1 hit
SUPFAMiSSF46689 SSF46689, 1 hit
PROSITEiView protein in PROSITE
PS00041 HTH_ARAC_FAMILY_1, 1 hit
PS01124 HTH_ARAC_FAMILY_2, 1 hit

Sequencei

Sequence statusi: Complete.

P36547-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKKTRTANLH HLYHEPLPEN LKLTPKVEVD NVHQRQTTDV YEHALTITAW
60 70 80 90 100
QQIYDQLHPG KFHGEFTEIL LDDIQVFREY TGLALRQSCL VWPNSFWFGI
110 120 130 140 150
PATRGEQGFI GSQCLGSAEI ATRPGGTEFE LSTPDDYTIL GVVLSEDVIT
160 170 180 190 200
RQANFLHNPD RVLHMLRNQS ALEVKEQHKA ALWGFVQQAL ATFCENPENL
210 220 230 240 250
HQPAVRKVLG DNLLMAMGAM LEEAQPMVTA ESISHQSYRR LLSRAREYVL
260 270 280 290 300
ENMSEPVTVL DLCNQLHVSR RTLQNAFHAI LGIGPNAWLK RIRLNAVRRE
310 320 330 340 350
LISPWSQSMT VKDAAMQWGF WHLGQFATDY QQLFSEKPSL TLHQRMREWG
Length:350
Mass (Da):40,160
Last modified:November 1, 1997 - v2
Checksum:i1281A43DC31DE845
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti276A → R in CAA53168 (PubMed:8300522).Curated1
Sequence conflicti285P → R in CAA53168 (PubMed:8300522).Curated1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X75413 Genomic DNA Translation: CAA53168.1
U00096 Genomic DNA Translation: AAC75490.1
AP009048 Genomic DNA Translation: BAA16320.1
PIRiD65018
RefSeqiNP_416932.1, NC_000913.3
WP_000753690.1, NZ_LN832404.1

Genome annotation databases

EnsemblBacteriaiAAC75490; AAC75490; b2437
BAA16320; BAA16320; BAA16320
GeneIDi946911
KEGGiecj:JW2430
eco:b2437
PATRICifig|1411691.4.peg.4294

Similar proteinsi

Entry informationi

Entry nameiEUTR_ECOLI
AccessioniPrimary (citable) accession number: P36547
Secondary accession number(s): P77451
Entry historyiIntegrated into UniProtKB/Swiss-Prot: June 1, 1994
Last sequence update: November 1, 1997
Last modified: March 28, 2018
This is version 128 of the entry and version 2 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Escherichia coli
    Escherichia coli (strain K12): entries and cross-references to EcoGene

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