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P36528 (RM17_YEAST) Reviewed, UniProtKB/Swiss-Prot

Last modified April 16, 2014. Version 109. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (4) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
54S ribosomal protein L17, mitochondrial
Alternative name(s):
YmL17/YmL30
Gene names
Name:MRPL17
Synonyms:MRPL30
Ordered Locus Names:YNL252C
ORF Names:N0864
OrganismSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) [Reference proteome]
Taxonomic identifier559292 [NCBI]
Taxonomic lineageEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces

Protein attributes

Sequence length281 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is further processed into a mature form.
Protein existenceEvidence at protein level

General annotation (Comments)

Subunit structure

Component of the mitochondrial large ribosomal subunit. Mature mitochondrial ribosomes consist of a small (37S) and a large (54S) subunit. The 37S subunit contains at least 33 different proteins and 1 molecule of RNA (15S). The 54S subunit contains at least 45 different proteins and 1 molecule of RNA (21S). Ref.5 Ref.6 Ref.7

Subcellular location

Mitochondrion Ref.8 Ref.10.

Miscellaneous

Present with 7400 molecules/cell in log phase SD medium.

Sequence similarities

Belongs to the ribosomal protein L46 family.

Ontologies

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Transit peptide1 – 1919Mitochondrion Ref.5
Chain20 – 28126254S ribosomal protein L17, mitochondrial
PRO_0000030578

Sequences

Sequence LengthMass (Da)Tools
P36528 [UniParc].

Last modified October 1, 1996. Version 2.
Checksum: BD4F2B6D7C2F44DB

FASTA28132,213
        10         20         30         40         50         60 
MKVNLMLKRG LATATATASS APPKIKVGVL LSRIPIIKSE LNELEKKYYE YQSELEKRLM 

        70         80         90        100        110        120 
WTFPAYFYFK KGTVAEHKFL SLQKGPISKK NGIWFPRGIP DIKHGRERST KQEVKLSDDS 

       130        140        150        160        170        180 
TVAFSNNQKE QSKDDVNRPV IPNDRITEAD RSNDMKSLER QLSRTLYLLV KDKSGTWKFP 

       190        200        210        220        230        240 
NFDLSDESKP LHVHAENELK LLSGDQIYTW SVSATPIGVL QDERNRTAEF IVKSHILAGK 

       250        260        270        280 
FDLVASKNDA FEDFAWLTKG EISEYVPKDY FNKTEFLLAD N 

« Hide

References

« Hide 'large scale' references
[1]"Sequence analysis of the 33 kb long region between ORC5 and SUI1 from the left arm of chromosome XIV from Saccharomyces cerevisiae."
Sen-Gupta M., Gueldener U., Beinhauer J.D., Fiedler T.A., Hegemann J.H.
Yeast 13:849-860(1997) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
Strain: ATCC 96604 / S288c / FY1679.
[2]"The nucleotide sequence of Saccharomyces cerevisiae chromosome XIV and its evolutionary implications."
Philippsen P., Kleine K., Poehlmann R., Duesterhoeft A., Hamberg K., Hegemann J.H., Obermaier B., Urrestarazu L.A., Aert R., Albermann K., Altmann R., Andre B., Baladron V., Ballesta J.P.G., Becam A.-M., Beinhauer J.D., Boskovic J., Buitrago M.J. expand/collapse author list , Bussereau F., Coster F., Crouzet M., D'Angelo M., Dal Pero F., De Antoni A., del Rey F., Doignon F., Domdey H., Dubois E., Fiedler T.A., Fleig U., Floeth M., Fritz C., Gaillardin C., Garcia-Cantalejo J.M., Glansdorff N., Goffeau A., Gueldener U., Herbert C.J., Heumann K., Heuss-Neitzel D., Hilbert H., Hinni K., Iraqui Houssaini I., Jacquet M., Jimenez A., Jonniaux J.-L., Karpfinger-Hartl L., Lanfranchi G., Lepingle A., Levesque H., Lyck R., Maftahi M., Mallet L., Maurer C.T.C., Messenguy F., Mewes H.-W., Moestl D., Nasr F., Nicaud J.-M., Niedenthal R.K., Pandolfo D., Pierard A., Piravandi E., Planta R.J., Pohl T.M., Purnelle B., Rebischung C., Remacha M.A., Revuelta J.L., Rinke M., Saiz J.E., Sartorello F., Scherens B., Sen-Gupta M., Soler-Mira A., Urbanus J.H.M., Valle G., Van Dyck L., Verhasselt P., Vierendeels F., Vissers S., Voet M., Volckaert G., Wach A., Wambutt R., Wedler H., Zollner A., Hani J.
Nature 387:93-98(1997) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 204508 / S288c.
[3]Saccharomyces Genome Database
Submitted (DEC-2009) to the EMBL/GenBank/DDBJ databases
Cited for: GENOME REANNOTATION.
Strain: ATCC 204508 / S288c.
[4]"Approaching a complete repository of sequence-verified protein-encoding clones for Saccharomyces cerevisiae."
Hu Y., Rolfs A., Bhullar B., Murthy T.V.S., Zhu C., Berger M.F., Camargo A.A., Kelley F., McCarron S., Jepson D., Richardson A., Raphael J., Moreira D., Taycher E., Zuo D., Mohr S., Kane M.F., Williamson J. expand/collapse author list , Simpson A.J.G., Bulyk M.L., Harlow E., Marsischky G., Kolodner R.D., LaBaer J.
Genome Res. 17:536-543(2007) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
Strain: ATCC 204508 / S288c.
[5]"Extended N-terminal sequencing of proteins of the large ribosomal subunit from yeast mitochondria."
Grohmann L., Graack H.-R., Kruft V., Choli T., Goldschmidt-Reisin S., Kitakawa M.
FEBS Lett. 284:51-56(1991) [PubMed] [Europe PMC] [Abstract]
Cited for: PROTEIN SEQUENCE OF 20-40, SUBUNIT.
Strain: 07173.
[6]"Identification and characterization of the genes for mitochondrial ribosomal proteins of Saccharomyces cerevisiae."
Kitakawa M., Graack H.-R., Grohmann L., Goldschmidt-Reisin S., Herfurth E., Wittmann-Liebold B., Nishimura T., Isono K.
Eur. J. Biochem. 245:449-456(1997) [PubMed] [Europe PMC] [Abstract]
Cited for: PROTEIN SEQUENCE OF 157-169, SUBUNIT.
Strain: 07173.
[7]"Tag-mediated isolation of yeast mitochondrial ribosome and mass spectrometric identification of its new components."
Gan X., Kitakawa M., Yoshino K., Oshiro N., Yonezawa K., Isono K.
Eur. J. Biochem. 269:5203-5214(2002) [PubMed] [Europe PMC] [Abstract]
Cited for: IDENTIFICATION IN THE MITOCHONDRIAL RIBOSOMAL LARGE COMPLEX, IDENTIFICATION BY MASS SPECTROMETRY.
[8]"Global analysis of protein localization in budding yeast."
Huh W.-K., Falvo J.V., Gerke L.C., Carroll A.S., Howson R.W., Weissman J.S., O'Shea E.K.
Nature 425:686-691(2003) [PubMed] [Europe PMC] [Abstract]
Cited for: SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS].
[9]"Global analysis of protein expression in yeast."
Ghaemmaghami S., Huh W.-K., Bower K., Howson R.W., Belle A., Dephoure N., O'Shea E.K., Weissman J.S.
Nature 425:737-741(2003) [PubMed] [Europe PMC] [Abstract]
Cited for: LEVEL OF PROTEIN EXPRESSION [LARGE SCALE ANALYSIS].
[10]"The proteome of Saccharomyces cerevisiae mitochondria."
Sickmann A., Reinders J., Wagner Y., Joppich C., Zahedi R.P., Meyer H.E., Schoenfisch B., Perschil I., Chacinska A., Guiard B., Rehling P., Pfanner N., Meisinger C.
Proc. Natl. Acad. Sci. U.S.A. 100:13207-13212(2003) [PubMed] [Europe PMC] [Abstract]
Cited for: SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS].
Strain: ATCC 76625 / YPH499.
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
X96722 Genomic DNA. Translation: CAA65492.1.
Z71528 Genomic DNA. Translation: CAA96159.1.
AY558015 Genomic DNA. Translation: AAS56341.1.
BK006947 Genomic DNA. Translation: DAA10307.1.
PIRS63225.
RefSeqNP_014147.1. NM_001183090.1.

3D structure databases

ProteinModelPortalP36528.
SMRP36528. Positions 154-214.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

BioGrid35587. 42 interactions.
DIPDIP-4278N.
IntActP36528. 7 interactions.
MINTMINT-487311.
STRING4932.YNL252C.

Proteomic databases

PaxDbP36528.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblFungiYNL252C; YNL252C; YNL252C.
GeneID855469.
KEGGsce:YNL252C.

Organism-specific databases

CYGDYNL252c.
SGDS000005196. MRPL17.

Phylogenomic databases

eggNOGNOG256490.
HOGENOMHOG000248758.
KOK17427.
OMALKGRIMA.
OrthoDBEOG780RXX.

Enzyme and pathway databases

BioCycYEAST:G3O-33249-MONOMER.

Gene expression databases

GenevestigatorP36528.

Family and domain databases

InterProIPR021757. Ribosomal_L46.
[Graphical view]
PfamPF11788. MRP-L46. 1 hit.
[Graphical view]
ProtoNetSearch...

Other

NextBio979412.

Entry information

Entry nameRM17_YEAST
AccessionPrimary (citable) accession number: P36528
Secondary accession number(s): D6W0U1
Entry history
Integrated into UniProtKB/Swiss-Prot: June 1, 1994
Last sequence update: October 1, 1996
Last modified: April 16, 2014
This is version 109 of the entry and version 2 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Relevant documents

Yeast chromosome XIV

Yeast (Saccharomyces cerevisiae) chromosome XIV: entries and gene names

Yeast

Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD

SIMILARITY comments

Index of protein domains and families

Ribosomal proteins

Ribosomal proteins families and list of entries