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P36528

- RM17_YEAST

UniProt

P36528 - RM17_YEAST

Protein

54S ribosomal protein L17, mitochondrial

Gene

MRPL17

Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Status
Reviewed - Annotation score: 3 out of 5- Experimental evidence at protein leveli
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    • History
      Entry version 112 (01 Oct 2014)
      Sequence version 2 (01 Oct 1996)
      Previous versions | rss
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    Functioni

    GO - Molecular functioni

    1. structural constituent of ribosome Source: SGD

    GO - Biological processi

    1. mitochondrial translation Source: SGD

    Keywords - Molecular functioni

    Ribonucleoprotein, Ribosomal protein

    Enzyme and pathway databases

    BioCyciYEAST:G3O-33249-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    54S ribosomal protein L17, mitochondrial
    Alternative name(s):
    YmL17/YmL30
    Gene namesi
    Name:MRPL17
    Synonyms:MRPL30
    Ordered Locus Names:YNL252C
    ORF Names:N0864
    OrganismiSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
    Taxonomic identifieri559292 [NCBI]
    Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces
    ProteomesiUP000002311: Chromosome XIV

    Organism-specific databases

    CYGDiYNL252c.
    SGDiS000005196. MRPL17.

    Subcellular locationi

    Mitochondrion 2 Publications

    GO - Cellular componenti

    1. mitochondrial large ribosomal subunit Source: SGD

    Keywords - Cellular componenti

    Mitochondrion

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Transit peptidei1 – 1919Mitochondrion1 PublicationAdd
    BLAST
    Chaini20 – 28126254S ribosomal protein L17, mitochondrialPRO_0000030578Add
    BLAST

    Proteomic databases

    MaxQBiP36528.
    PaxDbiP36528.

    Expressioni

    Gene expression databases

    GenevestigatoriP36528.

    Interactioni

    Subunit structurei

    Component of the mitochondrial large ribosomal subunit. Mature mitochondrial ribosomes consist of a small (37S) and a large (54S) subunit. The 37S subunit contains at least 33 different proteins and 1 molecule of RNA (15S). The 54S subunit contains at least 45 different proteins and 1 molecule of RNA (21S).3 Publications

    Protein-protein interaction databases

    BioGridi35587. 42 interactions.
    DIPiDIP-4278N.
    IntActiP36528. 7 interactions.
    MINTiMINT-487311.
    STRINGi4932.YNL252C.

    Structurei

    3D structure databases

    Select the link destinations:
    PDBe
    RCSB PDB
    PDBj
    Links Updated
    EntryMethodResolution (Å)ChainPositionsPDBsum
    1VW4electron microscopy3.2061-281[»]
    ProteinModelPortaliP36528.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the ribosomal protein L46 family.Curated

    Keywords - Domaini

    Transit peptide

    Phylogenomic databases

    eggNOGiNOG256490.
    HOGENOMiHOG000248758.
    KOiK17427.
    OMAiLKGRIMA.
    OrthoDBiEOG780RXX.

    Family and domain databases

    InterProiIPR021757. Ribosomal_L46.
    [Graphical view]
    PfamiPF11788. MRP-L46. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Sequence processingi: The displayed sequence is further processed into a mature form.

    P36528-1 [UniParc]FASTAAdd to Basket

    « Hide

    MKVNLMLKRG LATATATASS APPKIKVGVL LSRIPIIKSE LNELEKKYYE    50
    YQSELEKRLM WTFPAYFYFK KGTVAEHKFL SLQKGPISKK NGIWFPRGIP 100
    DIKHGRERST KQEVKLSDDS TVAFSNNQKE QSKDDVNRPV IPNDRITEAD 150
    RSNDMKSLER QLSRTLYLLV KDKSGTWKFP NFDLSDESKP LHVHAENELK 200
    LLSGDQIYTW SVSATPIGVL QDERNRTAEF IVKSHILAGK FDLVASKNDA 250
    FEDFAWLTKG EISEYVPKDY FNKTEFLLAD N 281
    Length:281
    Mass (Da):32,213
    Last modified:October 1, 1996 - v2
    Checksum:iBD4F2B6D7C2F44DB
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    X96722 Genomic DNA. Translation: CAA65492.1.
    Z71528 Genomic DNA. Translation: CAA96159.1.
    AY558015 Genomic DNA. Translation: AAS56341.1.
    BK006947 Genomic DNA. Translation: DAA10307.1.
    PIRiS63225.
    RefSeqiNP_014147.1. NM_001183090.1.

    Genome annotation databases

    EnsemblFungiiYNL252C; YNL252C; YNL252C.
    GeneIDi855469.
    KEGGisce:YNL252C.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    X96722 Genomic DNA. Translation: CAA65492.1 .
    Z71528 Genomic DNA. Translation: CAA96159.1 .
    AY558015 Genomic DNA. Translation: AAS56341.1 .
    BK006947 Genomic DNA. Translation: DAA10307.1 .
    PIRi S63225.
    RefSeqi NP_014147.1. NM_001183090.1.

    3D structure databases

    Select the link destinations:
    PDBe
    RCSB PDB
    PDBj
    Links Updated
    Entry Method Resolution (Å) Chain Positions PDBsum
    1VW4 electron microscopy 3.20 6 1-281 [» ]
    ProteinModelPortali P36528.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    BioGridi 35587. 42 interactions.
    DIPi DIP-4278N.
    IntActi P36528. 7 interactions.
    MINTi MINT-487311.
    STRINGi 4932.YNL252C.

    Proteomic databases

    MaxQBi P36528.
    PaxDbi P36528.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblFungii YNL252C ; YNL252C ; YNL252C .
    GeneIDi 855469.
    KEGGi sce:YNL252C.

    Organism-specific databases

    CYGDi YNL252c.
    SGDi S000005196. MRPL17.

    Phylogenomic databases

    eggNOGi NOG256490.
    HOGENOMi HOG000248758.
    KOi K17427.
    OMAi LKGRIMA.
    OrthoDBi EOG780RXX.

    Enzyme and pathway databases

    BioCyci YEAST:G3O-33249-MONOMER.

    Miscellaneous databases

    NextBioi 979412.

    Gene expression databases

    Genevestigatori P36528.

    Family and domain databases

    InterProi IPR021757. Ribosomal_L46.
    [Graphical view ]
    Pfami PF11788. MRP-L46. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Sequence analysis of the 33 kb long region between ORC5 and SUI1 from the left arm of chromosome XIV from Saccharomyces cerevisiae."
      Sen-Gupta M., Gueldener U., Beinhauer J.D., Fiedler T.A., Hegemann J.H.
      Yeast 13:849-860(1997) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
      Strain: ATCC 96604 / S288c / FY1679.
    2. "The nucleotide sequence of Saccharomyces cerevisiae chromosome XIV and its evolutionary implications."
      Philippsen P., Kleine K., Poehlmann R., Duesterhoeft A., Hamberg K., Hegemann J.H., Obermaier B., Urrestarazu L.A., Aert R., Albermann K., Altmann R., Andre B., Baladron V., Ballesta J.P.G., Becam A.-M., Beinhauer J.D., Boskovic J., Buitrago M.J.
      , Bussereau F., Coster F., Crouzet M., D'Angelo M., Dal Pero F., De Antoni A., del Rey F., Doignon F., Domdey H., Dubois E., Fiedler T.A., Fleig U., Floeth M., Fritz C., Gaillardin C., Garcia-Cantalejo J.M., Glansdorff N., Goffeau A., Gueldener U., Herbert C.J., Heumann K., Heuss-Neitzel D., Hilbert H., Hinni K., Iraqui Houssaini I., Jacquet M., Jimenez A., Jonniaux J.-L., Karpfinger-Hartl L., Lanfranchi G., Lepingle A., Levesque H., Lyck R., Maftahi M., Mallet L., Maurer C.T.C., Messenguy F., Mewes H.-W., Moestl D., Nasr F., Nicaud J.-M., Niedenthal R.K., Pandolfo D., Pierard A., Piravandi E., Planta R.J., Pohl T.M., Purnelle B., Rebischung C., Remacha M.A., Revuelta J.L., Rinke M., Saiz J.E., Sartorello F., Scherens B., Sen-Gupta M., Soler-Mira A., Urbanus J.H.M., Valle G., Van Dyck L., Verhasselt P., Vierendeels F., Vissers S., Voet M., Volckaert G., Wach A., Wambutt R., Wedler H., Zollner A., Hani J.
      Nature 387:93-98(1997) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: ATCC 204508 / S288c.
    3. Cited for: GENOME REANNOTATION.
      Strain: ATCC 204508 / S288c.
    4. Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
      Strain: ATCC 204508 / S288c.
    5. "Extended N-terminal sequencing of proteins of the large ribosomal subunit from yeast mitochondria."
      Grohmann L., Graack H.-R., Kruft V., Choli T., Goldschmidt-Reisin S., Kitakawa M.
      FEBS Lett. 284:51-56(1991) [PubMed] [Europe PMC] [Abstract]
      Cited for: PROTEIN SEQUENCE OF 20-40, SUBUNIT.
      Strain: 07173.
    6. "Identification and characterization of the genes for mitochondrial ribosomal proteins of Saccharomyces cerevisiae."
      Kitakawa M., Graack H.-R., Grohmann L., Goldschmidt-Reisin S., Herfurth E., Wittmann-Liebold B., Nishimura T., Isono K.
      Eur. J. Biochem. 245:449-456(1997) [PubMed] [Europe PMC] [Abstract]
      Cited for: PROTEIN SEQUENCE OF 157-169, SUBUNIT.
      Strain: 07173.
    7. "Tag-mediated isolation of yeast mitochondrial ribosome and mass spectrometric identification of its new components."
      Gan X., Kitakawa M., Yoshino K., Oshiro N., Yonezawa K., Isono K.
      Eur. J. Biochem. 269:5203-5214(2002) [PubMed] [Europe PMC] [Abstract]
      Cited for: IDENTIFICATION IN THE MITOCHONDRIAL RIBOSOMAL LARGE COMPLEX, IDENTIFICATION BY MASS SPECTROMETRY.
    8. Cited for: SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS].
    9. Cited for: LEVEL OF PROTEIN EXPRESSION [LARGE SCALE ANALYSIS].
    10. Cited for: SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS].
      Strain: ATCC 76625 / YPH499.

    Entry informationi

    Entry nameiRM17_YEAST
    AccessioniPrimary (citable) accession number: P36528
    Secondary accession number(s): D6W0U1
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: June 1, 1994
    Last sequence update: October 1, 1996
    Last modified: October 1, 2014
    This is version 112 of the entry and version 2 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programFungal Protein Annotation Program

    Miscellaneousi

    Miscellaneous

    Present with 7400 molecules/cell in log phase SD medium.1 Publication

    Keywords - Technical termi

    3D-structure, Complete proteome, Direct protein sequencing, Reference proteome

    Documents

    1. PDB cross-references
      Index of Protein Data Bank (PDB) cross-references
    2. Ribosomal proteins
      Ribosomal proteins families and list of entries
    3. SIMILARITY comments
      Index of protein domains and families
    4. Yeast
      Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD
    5. Yeast chromosome XIV
      Yeast (Saccharomyces cerevisiae) chromosome XIV: entries and gene names

    External Data

    Dasty 3