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P36528

- RM17_YEAST

UniProt

P36528 - RM17_YEAST

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Protein

54S ribosomal protein L17, mitochondrial

Gene

MRPL17

Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Status
Reviewed - Annotation score: 3 out of 5- Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

  1. structural constituent of ribosome Source: SGD

GO - Biological processi

  1. mitochondrial translation Source: SGD
Complete GO annotation...

Keywords - Molecular functioni

Ribonucleoprotein, Ribosomal protein

Enzyme and pathway databases

BioCyciYEAST:G3O-33249-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
54S ribosomal protein L17, mitochondrial
Alternative name(s):
YmL17/YmL30
Gene namesi
Name:MRPL17
Synonyms:MRPL30
Ordered Locus Names:YNL252C
ORF Names:N0864
OrganismiSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Taxonomic identifieri559292 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces
ProteomesiUP000002311: Chromosome XIV

Organism-specific databases

CYGDiYNL252c.
SGDiS000005196. MRPL17.

Subcellular locationi

Mitochondrion 2 Publications

GO - Cellular componenti

  1. mitochondrial large ribosomal subunit Source: SGD
Complete GO annotation...

Keywords - Cellular componenti

Mitochondrion

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transit peptidei1 – 1919Mitochondrion1 PublicationAdd
BLAST
Chaini20 – 28126254S ribosomal protein L17, mitochondrialPRO_0000030578Add
BLAST

Proteomic databases

MaxQBiP36528.
PaxDbiP36528.

Expressioni

Gene expression databases

GenevestigatoriP36528.

Interactioni

Subunit structurei

Component of the mitochondrial large ribosomal subunit. Mature mitochondrial ribosomes consist of a small (37S) and a large (54S) subunit. The 37S subunit contains at least 33 different proteins and 1 molecule of RNA (15S). The 54S subunit contains at least 45 different proteins and 1 molecule of RNA (21S).3 Publications

Protein-protein interaction databases

BioGridi35587. 42 interactions.
DIPiDIP-4278N.
IntActiP36528. 7 interactions.
MINTiMINT-487311.
STRINGi4932.YNL252C.

Structurei

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
1VW4electron microscopy3.2061-281[»]
ProteinModelPortaliP36528.
SMRiP36528. Positions 23-280.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the ribosomal protein L46 family.Curated

Keywords - Domaini

Transit peptide

Phylogenomic databases

eggNOGiNOG256490.
HOGENOMiHOG000248758.
InParanoidiP36528.
KOiK17427.
OMAiLKGRIMA.
OrthoDBiEOG780RXX.

Family and domain databases

InterProiIPR021757. Ribosomal_L46.
[Graphical view]
PfamiPF11788. MRP-L46. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

P36528-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MKVNLMLKRG LATATATASS APPKIKVGVL LSRIPIIKSE LNELEKKYYE
60 70 80 90 100
YQSELEKRLM WTFPAYFYFK KGTVAEHKFL SLQKGPISKK NGIWFPRGIP
110 120 130 140 150
DIKHGRERST KQEVKLSDDS TVAFSNNQKE QSKDDVNRPV IPNDRITEAD
160 170 180 190 200
RSNDMKSLER QLSRTLYLLV KDKSGTWKFP NFDLSDESKP LHVHAENELK
210 220 230 240 250
LLSGDQIYTW SVSATPIGVL QDERNRTAEF IVKSHILAGK FDLVASKNDA
260 270 280
FEDFAWLTKG EISEYVPKDY FNKTEFLLAD N
Length:281
Mass (Da):32,213
Last modified:October 1, 1996 - v2
Checksum:iBD4F2B6D7C2F44DB
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X96722 Genomic DNA. Translation: CAA65492.1.
Z71528 Genomic DNA. Translation: CAA96159.1.
AY558015 Genomic DNA. Translation: AAS56341.1.
BK006947 Genomic DNA. Translation: DAA10307.1.
PIRiS63225.
RefSeqiNP_014147.1. NM_001183090.1.

Genome annotation databases

EnsemblFungiiYNL252C; YNL252C; YNL252C.
GeneIDi855469.
KEGGisce:YNL252C.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X96722 Genomic DNA. Translation: CAA65492.1 .
Z71528 Genomic DNA. Translation: CAA96159.1 .
AY558015 Genomic DNA. Translation: AAS56341.1 .
BK006947 Genomic DNA. Translation: DAA10307.1 .
PIRi S63225.
RefSeqi NP_014147.1. NM_001183090.1.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
Entry Method Resolution (Å) Chain Positions PDBsum
1VW4 electron microscopy 3.20 6 1-281 [» ]
ProteinModelPortali P36528.
SMRi P36528. Positions 23-280.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

BioGridi 35587. 42 interactions.
DIPi DIP-4278N.
IntActi P36528. 7 interactions.
MINTi MINT-487311.
STRINGi 4932.YNL252C.

Proteomic databases

MaxQBi P36528.
PaxDbi P36528.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblFungii YNL252C ; YNL252C ; YNL252C .
GeneIDi 855469.
KEGGi sce:YNL252C.

Organism-specific databases

CYGDi YNL252c.
SGDi S000005196. MRPL17.

Phylogenomic databases

eggNOGi NOG256490.
HOGENOMi HOG000248758.
InParanoidi P36528.
KOi K17427.
OMAi LKGRIMA.
OrthoDBi EOG780RXX.

Enzyme and pathway databases

BioCyci YEAST:G3O-33249-MONOMER.

Miscellaneous databases

NextBioi 979412.

Gene expression databases

Genevestigatori P36528.

Family and domain databases

InterProi IPR021757. Ribosomal_L46.
[Graphical view ]
Pfami PF11788. MRP-L46. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "Sequence analysis of the 33 kb long region between ORC5 and SUI1 from the left arm of chromosome XIV from Saccharomyces cerevisiae."
    Sen-Gupta M., Gueldener U., Beinhauer J.D., Fiedler T.A., Hegemann J.H.
    Yeast 13:849-860(1997) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
    Strain: ATCC 96604 / S288c / FY1679.
  2. "The nucleotide sequence of Saccharomyces cerevisiae chromosome XIV and its evolutionary implications."
    Philippsen P., Kleine K., Poehlmann R., Duesterhoeft A., Hamberg K., Hegemann J.H., Obermaier B., Urrestarazu L.A., Aert R., Albermann K., Altmann R., Andre B., Baladron V., Ballesta J.P.G., Becam A.-M., Beinhauer J.D., Boskovic J., Buitrago M.J.
    , Bussereau F., Coster F., Crouzet M., D'Angelo M., Dal Pero F., De Antoni A., del Rey F., Doignon F., Domdey H., Dubois E., Fiedler T.A., Fleig U., Floeth M., Fritz C., Gaillardin C., Garcia-Cantalejo J.M., Glansdorff N., Goffeau A., Gueldener U., Herbert C.J., Heumann K., Heuss-Neitzel D., Hilbert H., Hinni K., Iraqui Houssaini I., Jacquet M., Jimenez A., Jonniaux J.-L., Karpfinger-Hartl L., Lanfranchi G., Lepingle A., Levesque H., Lyck R., Maftahi M., Mallet L., Maurer C.T.C., Messenguy F., Mewes H.-W., Moestl D., Nasr F., Nicaud J.-M., Niedenthal R.K., Pandolfo D., Pierard A., Piravandi E., Planta R.J., Pohl T.M., Purnelle B., Rebischung C., Remacha M.A., Revuelta J.L., Rinke M., Saiz J.E., Sartorello F., Scherens B., Sen-Gupta M., Soler-Mira A., Urbanus J.H.M., Valle G., Van Dyck L., Verhasselt P., Vierendeels F., Vissers S., Voet M., Volckaert G., Wach A., Wambutt R., Wedler H., Zollner A., Hani J.
    Nature 387:93-98(1997) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 204508 / S288c.
  3. Cited for: GENOME REANNOTATION.
    Strain: ATCC 204508 / S288c.
  4. Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
    Strain: ATCC 204508 / S288c.
  5. "Extended N-terminal sequencing of proteins of the large ribosomal subunit from yeast mitochondria."
    Grohmann L., Graack H.-R., Kruft V., Choli T., Goldschmidt-Reisin S., Kitakawa M.
    FEBS Lett. 284:51-56(1991) [PubMed] [Europe PMC] [Abstract]
    Cited for: PROTEIN SEQUENCE OF 20-40, SUBUNIT.
    Strain: 07173.
  6. "Identification and characterization of the genes for mitochondrial ribosomal proteins of Saccharomyces cerevisiae."
    Kitakawa M., Graack H.-R., Grohmann L., Goldschmidt-Reisin S., Herfurth E., Wittmann-Liebold B., Nishimura T., Isono K.
    Eur. J. Biochem. 245:449-456(1997) [PubMed] [Europe PMC] [Abstract]
    Cited for: PROTEIN SEQUENCE OF 157-169, SUBUNIT.
    Strain: 07173.
  7. "Tag-mediated isolation of yeast mitochondrial ribosome and mass spectrometric identification of its new components."
    Gan X., Kitakawa M., Yoshino K., Oshiro N., Yonezawa K., Isono K.
    Eur. J. Biochem. 269:5203-5214(2002) [PubMed] [Europe PMC] [Abstract]
    Cited for: IDENTIFICATION IN THE MITOCHONDRIAL RIBOSOMAL LARGE COMPLEX, IDENTIFICATION BY MASS SPECTROMETRY.
  8. Cited for: SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS].
  9. Cited for: LEVEL OF PROTEIN EXPRESSION [LARGE SCALE ANALYSIS].
  10. Cited for: SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS].
    Strain: ATCC 76625 / YPH499.

Entry informationi

Entry nameiRM17_YEAST
AccessioniPrimary (citable) accession number: P36528
Secondary accession number(s): D6W0U1
Entry historyi
Integrated into UniProtKB/Swiss-Prot: June 1, 1994
Last sequence update: October 1, 1996
Last modified: October 29, 2014
This is version 113 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Miscellaneous

Present with 7400 molecules/cell in log phase SD medium.1 Publication

Keywords - Technical termi

3D-structure, Complete proteome, Direct protein sequencing, Reference proteome

Documents

  1. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  2. Ribosomal proteins
    Ribosomal proteins families and list of entries
  3. SIMILARITY comments
    Index of protein domains and families
  4. Yeast
    Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD
  5. Yeast chromosome XIV
    Yeast (Saccharomyces cerevisiae) chromosome XIV: entries and gene names

External Data

Dasty 3