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P36520

- RM10_YEAST

UniProt

P36520 - RM10_YEAST

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Protein

54S ribosomal protein L10, mitochondrial

Gene

MRPL10

Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Status
Reviewed - Annotation score: 3 out of 5- Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

  1. structural constituent of ribosome Source: SGD

GO - Biological processi

  1. mitochondrial translation Source: SGD
Complete GO annotation...

Keywords - Molecular functioni

Ribonucleoprotein, Ribosomal protein

Enzyme and pathway databases

BioCyciYEAST:G3O-33275-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
54S ribosomal protein L10, mitochondrial
Alternative name(s):
YmL10/YmL18
Gene namesi
Name:MRPL10
Synonyms:MRPL18
Ordered Locus Names:YNL284C
ORF Names:N0580
OrganismiSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Taxonomic identifieri559292 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces
ProteomesiUP000002311: Chromosome XIV

Organism-specific databases

CYGDiYNL284c.
SGDiS000005228. MRPL10.

Subcellular locationi

Mitochondrion 2 Publications

GO - Cellular componenti

  1. mitochondrial large ribosomal subunit Source: SGD
Complete GO annotation...

Keywords - Cellular componenti

Mitochondrion

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transit peptidei1 – 5757Mitochondrion1 PublicationAdd
BLAST
Chaini58 – 32226554S ribosomal protein L10, mitochondrialPRO_0000030468Add
BLAST

Proteomic databases

MaxQBiP36520.
PaxDbiP36520.

Expressioni

Gene expression databases

GenevestigatoriP36520.

Interactioni

Subunit structurei

Component of the mitochondrial large ribosomal subunit. Mature mitochondrial ribosomes consist of a small (37S) and a large (54S) subunit. The 37S subunit contains at least 33 different proteins and 1 molecule of RNA (15S). The 54S subunit contains at least 45 different proteins and 1 molecule of RNA (21S).2 Publications

Protein-protein interaction databases

BioGridi35556. 48 interactions.
DIPiDIP-6771N.
IntActiP36520. 37 interactions.
MINTiMINT-613283.
STRINGi4932.YNL284C.

Structurei

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
1VW4electron microscopy3.20J1-322[»]
ProteinModelPortaliP36520.
SMRiP36520. Positions 58-277.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the ribosomal protein L15P family.Curated

Keywords - Domaini

Transit peptide

Phylogenomic databases

eggNOGiCOG0200.
GeneTreeiENSGT00390000009040.
HOGENOMiHOG000231264.
InParanoidiP36520.
KOiK02876.
OMAiPHWFLEK.
OrthoDBiEOG7C2RBK.

Family and domain databases

HAMAPiMF_01341. Ribosomal_L15.
InterProiIPR005749. Ribosomal_L15_bac-type.
IPR021131. Ribosomal_L18e/L15P.
[Graphical view]
PANTHERiPTHR12934. PTHR12934. 1 hit.
PfamiPF00828. Ribosomal_L18e. 1 hit.
[Graphical view]
SUPFAMiSSF52080. SSF52080. 1 hit.
TIGRFAMsiTIGR01071. rplO_bact. 1 hit.

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

P36520-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MKAERQTGLR NSFTTVIGRK LINTFVPSMM LTSVAGNDIF FRGLFKSPVL
60 70 80 90 100
AFQSYRYVSI LGQLKPSDGS TKSFKRLGRG PSSGLGKTSG RGQKGQKARG
110 120 130 140 150
KVKSWFEGGQ TPIYKLFPKI GFTNVGAKPL KELNLKRIQW FHDKNRLHLQ
160 170 180 190 200
PGEVLDMNKM RKLGLVTGPI KYGVKILASG KFHYNLPIAL EASRASAKAI
210 220 230 240 250
AAIEKAGGKF TARYYTPLGL RAHLNPQWFL EKRGRVPLQA RPTKRRDIDF
260 270 280 290 300
YSKEEKRGYL VMEKDKLLQD IKEAQNKGSR HFLKQNVKKS SLEIELEELS
310 320
PEKDWVPVVS NSKVMNIKAL DH
Length:322
Mass (Da):36,347
Last modified:October 1, 1996 - v2
Checksum:iFD56AB98F62B4A07
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Sequence conflicti68 – 681D → K AA sequence (PubMed:2060626)Curated
Sequence conflicti71 – 711T → G AA sequence (PubMed:2060626)Curated
Sequence conflicti182 – 1821F → I AA sequence (PubMed:9151978)Curated
Sequence conflicti188 – 1881I → K AA sequence (PubMed:9151978)Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
Z71560 Genomic DNA. Translation: CAA96198.1.
BK006947 Genomic DNA. Translation: DAA10276.1.
PIRiS63258.
RefSeqiNP_014115.1. NM_001183122.1.

Genome annotation databases

EnsemblFungiiYNL284C; YNL284C; YNL284C.
GeneIDi855436.
KEGGisce:YNL284C.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
Z71560 Genomic DNA. Translation: CAA96198.1 .
BK006947 Genomic DNA. Translation: DAA10276.1 .
PIRi S63258.
RefSeqi NP_014115.1. NM_001183122.1.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
Entry Method Resolution (Å) Chain Positions PDBsum
1VW4 electron microscopy 3.20 J 1-322 [» ]
ProteinModelPortali P36520.
SMRi P36520. Positions 58-277.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

BioGridi 35556. 48 interactions.
DIPi DIP-6771N.
IntActi P36520. 37 interactions.
MINTi MINT-613283.
STRINGi 4932.YNL284C.

Proteomic databases

MaxQBi P36520.
PaxDbi P36520.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblFungii YNL284C ; YNL284C ; YNL284C .
GeneIDi 855436.
KEGGi sce:YNL284C.

Organism-specific databases

CYGDi YNL284c.
SGDi S000005228. MRPL10.

Phylogenomic databases

eggNOGi COG0200.
GeneTreei ENSGT00390000009040.
HOGENOMi HOG000231264.
InParanoidi P36520.
KOi K02876.
OMAi PHWFLEK.
OrthoDBi EOG7C2RBK.

Enzyme and pathway databases

BioCyci YEAST:G3O-33275-MONOMER.

Miscellaneous databases

NextBioi 979320.
PROi P36520.

Gene expression databases

Genevestigatori P36520.

Family and domain databases

HAMAPi MF_01341. Ribosomal_L15.
InterProi IPR005749. Ribosomal_L15_bac-type.
IPR021131. Ribosomal_L18e/L15P.
[Graphical view ]
PANTHERi PTHR12934. PTHR12934. 1 hit.
Pfami PF00828. Ribosomal_L18e. 1 hit.
[Graphical view ]
SUPFAMi SSF52080. SSF52080. 1 hit.
TIGRFAMsi TIGR01071. rplO_bact. 1 hit.
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "The nucleotide sequence of Saccharomyces cerevisiae chromosome XIV and its evolutionary implications."
    Philippsen P., Kleine K., Poehlmann R., Duesterhoeft A., Hamberg K., Hegemann J.H., Obermaier B., Urrestarazu L.A., Aert R., Albermann K., Altmann R., Andre B., Baladron V., Ballesta J.P.G., Becam A.-M., Beinhauer J.D., Boskovic J., Buitrago M.J.
    , Bussereau F., Coster F., Crouzet M., D'Angelo M., Dal Pero F., De Antoni A., del Rey F., Doignon F., Domdey H., Dubois E., Fiedler T.A., Fleig U., Floeth M., Fritz C., Gaillardin C., Garcia-Cantalejo J.M., Glansdorff N., Goffeau A., Gueldener U., Herbert C.J., Heumann K., Heuss-Neitzel D., Hilbert H., Hinni K., Iraqui Houssaini I., Jacquet M., Jimenez A., Jonniaux J.-L., Karpfinger-Hartl L., Lanfranchi G., Lepingle A., Levesque H., Lyck R., Maftahi M., Mallet L., Maurer C.T.C., Messenguy F., Mewes H.-W., Moestl D., Nasr F., Nicaud J.-M., Niedenthal R.K., Pandolfo D., Pierard A., Piravandi E., Planta R.J., Pohl T.M., Purnelle B., Rebischung C., Remacha M.A., Revuelta J.L., Rinke M., Saiz J.E., Sartorello F., Scherens B., Sen-Gupta M., Soler-Mira A., Urbanus J.H.M., Valle G., Van Dyck L., Verhasselt P., Vierendeels F., Vissers S., Voet M., Volckaert G., Wach A., Wambutt R., Wedler H., Zollner A., Hani J.
    Nature 387:93-98(1997) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 204508 / S288c.
  2. Cited for: GENOME REANNOTATION.
    Strain: ATCC 204508 / S288c.
  3. "Extended N-terminal sequencing of proteins of the large ribosomal subunit from yeast mitochondria."
    Grohmann L., Graack H.-R., Kruft V., Choli T., Goldschmidt-Reisin S., Kitakawa M.
    FEBS Lett. 284:51-56(1991) [PubMed] [Europe PMC] [Abstract]
    Cited for: PROTEIN SEQUENCE OF 58-71, SUBUNIT.
    Strain: 07173.
  4. "Identification and characterization of the genes for mitochondrial ribosomal proteins of Saccharomyces cerevisiae."
    Kitakawa M., Graack H.-R., Grohmann L., Goldschmidt-Reisin S., Herfurth E., Wittmann-Liebold B., Nishimura T., Isono K.
    Eur. J. Biochem. 245:449-456(1997) [PubMed] [Europe PMC] [Abstract]
    Cited for: PROTEIN SEQUENCE OF 182-195 AND 247-253, SUBUNIT.
    Strain: 07173.
  5. Cited for: SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS].
  6. Cited for: LEVEL OF PROTEIN EXPRESSION [LARGE SCALE ANALYSIS].
  7. Cited for: SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS].
    Strain: ATCC 76625 / YPH499.

Entry informationi

Entry nameiRM10_YEAST
AccessioniPrimary (citable) accession number: P36520
Secondary accession number(s): D6W0R0, P36524
Entry historyi
Integrated into UniProtKB/Swiss-Prot: June 1, 1994
Last sequence update: October 1, 1996
Last modified: October 29, 2014
This is version 122 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Miscellaneous

Present with 5350 molecules/cell in log phase SD medium.1 Publication

Keywords - Technical termi

3D-structure, Complete proteome, Direct protein sequencing, Reference proteome

Documents

  1. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  2. Ribosomal proteins
    Ribosomal proteins families and list of entries
  3. SIMILARITY comments
    Index of protein domains and families
  4. Yeast
    Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD
  5. Yeast chromosome XIV
    Yeast (Saccharomyces cerevisiae) chromosome XIV: entries and gene names

External Data

Dasty 3