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Protein

54S ribosomal protein L10, mitochondrial

Gene

MRPL10

Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

  • structural constituent of ribosome Source: SGD

GO - Biological processi

  • mitochondrial translation Source: SGD
Complete GO annotation...

Keywords - Molecular functioni

Ribonucleoprotein, Ribosomal protein

Enzyme and pathway databases

BioCyciYEAST:G3O-33275-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
54S ribosomal protein L10, mitochondrial
Alternative name(s):
YmL10/YmL18
Gene namesi
Name:MRPL10
Synonyms:MRPL18
Ordered Locus Names:YNL284C
ORF Names:N0580
OrganismiSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Taxonomic identifieri559292 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces
Proteomesi
  • UP000002311 Componenti: Chromosome XIV

Organism-specific databases

EuPathDBiFungiDB:YNL284C.
SGDiS000005228. MRPL10.

Subcellular locationi

GO - Cellular componenti

  • mitochondrial large ribosomal subunit Source: SGD
Complete GO annotation...

Keywords - Cellular componenti

Mitochondrion

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transit peptidei1 – 57Mitochondrion1 PublicationAdd BLAST57
ChainiPRO_000003046858 – 32254S ribosomal protein L10, mitochondrialAdd BLAST265

Proteomic databases

MaxQBiP36520.
PRIDEiP36520.

Interactioni

Subunit structurei

Component of the mitochondrial large ribosomal subunit. Mature mitochondrial ribosomes consist of a small (37S) and a large (54S) subunit. The 37S subunit contains at least 33 different proteins and 1 molecule of RNA (15S). The 54S subunit contains at least 45 different proteins and 1 molecule of RNA (21S).2 Publications

Protein-protein interaction databases

BioGridi35556. 50 interactors.
DIPiDIP-6771N.
IntActiP36520. 37 interactors.
MINTiMINT-613283.

Structurei

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
3J6Belectron microscopy3.20J1-322[»]
ProteinModelPortaliP36520.
SMRiP36520.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the ribosomal protein L15P family.Curated

Keywords - Domaini

Transit peptide

Phylogenomic databases

GeneTreeiENSGT00390000009040.
HOGENOMiHOG000231264.
InParanoidiP36520.
KOiK02876.
OMAiYLIMEND.
OrthoDBiEOG092C509P.

Family and domain databases

HAMAPiMF_01341. Ribosomal_L15. 1 hit.
InterProiIPR030878. Ribosomal_L15.
IPR005749. Ribosomal_L15_bac-type.
IPR021131. Ribosomal_L18e/L15P.
[Graphical view]
PANTHERiPTHR12934. PTHR12934. 1 hit.
PfamiPF00828. Ribosomal_L27A. 1 hit.
[Graphical view]
SUPFAMiSSF52080. SSF52080. 1 hit.
TIGRFAMsiTIGR01071. rplO_bact. 1 hit.

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

P36520-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKAERQTGLR NSFTTVIGRK LINTFVPSMM LTSVAGNDIF FRGLFKSPVL
60 70 80 90 100
AFQSYRYVSI LGQLKPSDGS TKSFKRLGRG PSSGLGKTSG RGQKGQKARG
110 120 130 140 150
KVKSWFEGGQ TPIYKLFPKI GFTNVGAKPL KELNLKRIQW FHDKNRLHLQ
160 170 180 190 200
PGEVLDMNKM RKLGLVTGPI KYGVKILASG KFHYNLPIAL EASRASAKAI
210 220 230 240 250
AAIEKAGGKF TARYYTPLGL RAHLNPQWFL EKRGRVPLQA RPTKRRDIDF
260 270 280 290 300
YSKEEKRGYL VMEKDKLLQD IKEAQNKGSR HFLKQNVKKS SLEIELEELS
310 320
PEKDWVPVVS NSKVMNIKAL DH
Length:322
Mass (Da):36,347
Last modified:October 1, 1996 - v2
Checksum:iFD56AB98F62B4A07
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti68D → K AA sequence (PubMed:2060626).Curated1
Sequence conflicti71T → G AA sequence (PubMed:2060626).Curated1
Sequence conflicti182F → I AA sequence (PubMed:9151978).Curated1
Sequence conflicti188I → K AA sequence (PubMed:9151978).Curated1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
Z71560 Genomic DNA. Translation: CAA96198.1.
BK006947 Genomic DNA. Translation: DAA10276.1.
PIRiS63258.
RefSeqiNP_014115.1. NM_001183122.1.

Genome annotation databases

EnsemblFungiiYNL284C; YNL284C; YNL284C.
GeneIDi855436.
KEGGisce:YNL284C.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
Z71560 Genomic DNA. Translation: CAA96198.1.
BK006947 Genomic DNA. Translation: DAA10276.1.
PIRiS63258.
RefSeqiNP_014115.1. NM_001183122.1.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
3J6Belectron microscopy3.20J1-322[»]
ProteinModelPortaliP36520.
SMRiP36520.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi35556. 50 interactors.
DIPiDIP-6771N.
IntActiP36520. 37 interactors.
MINTiMINT-613283.

Proteomic databases

MaxQBiP36520.
PRIDEiP36520.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblFungiiYNL284C; YNL284C; YNL284C.
GeneIDi855436.
KEGGisce:YNL284C.

Organism-specific databases

EuPathDBiFungiDB:YNL284C.
SGDiS000005228. MRPL10.

Phylogenomic databases

GeneTreeiENSGT00390000009040.
HOGENOMiHOG000231264.
InParanoidiP36520.
KOiK02876.
OMAiYLIMEND.
OrthoDBiEOG092C509P.

Enzyme and pathway databases

BioCyciYEAST:G3O-33275-MONOMER.

Miscellaneous databases

PROiP36520.

Family and domain databases

HAMAPiMF_01341. Ribosomal_L15. 1 hit.
InterProiIPR030878. Ribosomal_L15.
IPR005749. Ribosomal_L15_bac-type.
IPR021131. Ribosomal_L18e/L15P.
[Graphical view]
PANTHERiPTHR12934. PTHR12934. 1 hit.
PfamiPF00828. Ribosomal_L27A. 1 hit.
[Graphical view]
SUPFAMiSSF52080. SSF52080. 1 hit.
TIGRFAMsiTIGR01071. rplO_bact. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiRM10_YEAST
AccessioniPrimary (citable) accession number: P36520
Secondary accession number(s): D6W0R0, P36524
Entry historyi
Integrated into UniProtKB/Swiss-Prot: June 1, 1994
Last sequence update: October 1, 1996
Last modified: November 2, 2016
This is version 137 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Miscellaneous

Present with 5350 molecules/cell in log phase SD medium.1 Publication

Keywords - Technical termi

3D-structure, Complete proteome, Direct protein sequencing, Reference proteome

Documents

  1. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  2. Ribosomal proteins
    Ribosomal proteins families and list of entries
  3. SIMILARITY comments
    Index of protein domains and families
  4. Yeast
    Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD
  5. Yeast chromosome XIV
    Yeast (Saccharomyces cerevisiae) chromosome XIV: entries and gene names

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.