ID RL10_MYCGE Reviewed; 162 AA. AC P36263; DT 01-JUN-1994, integrated into UniProtKB/Swiss-Prot. DT 01-FEB-1996, sequence version 2. DT 27-MAR-2024, entry version 122. DE RecName: Full=Large ribosomal subunit protein uL10 {ECO:0000305}; DE AltName: Full=50S ribosomal protein L10; GN Name=rplJ; Synonyms=rpl10; OrderedLocusNames=MG361; OS Mycoplasma genitalium (strain ATCC 33530 / DSM 19775 / NCTC 10195 / G37) OS (Mycoplasmoides genitalium). OC Bacteria; Mycoplasmatota; Mycoplasmoidales; Mycoplasmoidaceae; OC Mycoplasmoides. OX NCBI_TaxID=243273; RN [1] RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=ATCC 33530 / DSM 19775 / NCTC 10195 / G37; RX PubMed=7569993; DOI=10.1126/science.270.5235.397; RA Fraser C.M., Gocayne J.D., White O., Adams M.D., Clayton R.A., RA Fleischmann R.D., Bult C.J., Kerlavage A.R., Sutton G.G., Kelley J.M., RA Fritchman J.L., Weidman J.F., Small K.V., Sandusky M., Fuhrmann J.L., RA Nguyen D.T., Utterback T.R., Saudek D.M., Phillips C.A., Merrick J.M., RA Tomb J.-F., Dougherty B.A., Bott K.F., Hu P.-C., Lucier T.S., RA Peterson S.N., Smith H.O., Hutchison C.A. III, Venter J.C.; RT "The minimal gene complement of Mycoplasma genitalium."; RL Science 270:397-403(1995). RN [2] RP NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 92-162. RC STRAIN=ATCC 33530 / DSM 19775 / NCTC 10195 / G37; RX PubMed=8253680; DOI=10.1128/jb.175.24.7918-7930.1993; RA Peterson S.N., Hu P.-C., Bott K.F., Hutchison C.A. III; RT "A survey of the Mycoplasma genitalium genome by using random sequencing."; RL J. Bacteriol. 175:7918-7930(1993). CC -!- FUNCTION: Forms part of the ribosomal stalk, playing a central role in CC the interaction of the ribosome with GTP-bound translation factors. CC {ECO:0000250}. CC -!- SUBUNIT: Part of the ribosomal stalk of the 50S ribosomal subunit. The CC N-terminus interacts with L11 and the large rRNA to form the base of CC the stalk. The C-terminus forms an elongated spine to which L12 dimers CC bind in a sequential fashion forming a multimeric L10(L12)X complex (By CC similarity). {ECO:0000250}. CC -!- SIMILARITY: Belongs to the universal ribosomal protein uL10 family. CC {ECO:0000305}. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; L43967; AAC71587.1; -; Genomic_DNA. DR EMBL; U02206; AAD12496.1; -; Genomic_DNA. DR PIR; I64239; I64239. DR RefSeq; WP_009885818.1; NZ_AAGX01000006.1. DR AlphaFoldDB; P36263; -. DR SMR; P36263; -. DR STRING; 243273.MG_361; -. DR KEGG; mge:MG_361; -. DR eggNOG; COG0244; Bacteria. DR HOGENOM; CLU_092227_1_2_14; -. DR InParanoid; P36263; -. DR OrthoDB; 9808307at2; -. DR BioCyc; MGEN243273:G1GJ2-454-MONOMER; -. DR Proteomes; UP000000807; Chromosome. DR GO; GO:0022625; C:cytosolic large ribosomal subunit; IBA:GO_Central. DR GO; GO:0070180; F:large ribosomal subunit rRNA binding; IEA:UniProtKB-UniRule. DR GO; GO:0003735; F:structural constituent of ribosome; IBA:GO_Central. DR GO; GO:0006412; P:translation; IBA:GO_Central. DR CDD; cd05797; Ribosomal_L10; 1. DR Gene3D; 3.30.70.1730; -; 1. DR Gene3D; 6.10.250.290; -; 1. DR HAMAP; MF_00362; Ribosomal_uL10; 1. DR InterPro; IPR001790; Ribosomal_uL10. DR InterPro; IPR043141; Ribosomal_uL10-like_sf. DR InterPro; IPR022973; Ribosomal_uL10_bac. DR InterPro; IPR047865; Ribosomal_uL10_bac_type. DR InterPro; IPR002363; Ribosomal_uL10_CS_bac. DR PANTHER; PTHR11560; 39S RIBOSOMAL PROTEIN L10, MITOCHONDRIAL; 1. DR PANTHER; PTHR11560:SF8; 39S RIBOSOMAL PROTEIN L10, MITOCHONDRIAL; 1. DR Pfam; PF00466; Ribosomal_L10; 1. DR SUPFAM; SSF160369; Ribosomal protein L10-like; 1. DR PROSITE; PS01109; RIBOSOMAL_L10; 1. PE 3: Inferred from homology; KW Reference proteome; Ribonucleoprotein; Ribosomal protein; RNA-binding; KW rRNA-binding. FT CHAIN 1..162 FT /note="Large ribosomal subunit protein uL10" FT /id="PRO_0000154665" SQ SEQUENCE 162 AA; 18261 MW; AC4CC72724389AEC CRC64; MVDSKKNKKQ QVTDFSNLLS QSKGFVIFDY SGMSAVDATL MRKKLFNKGS KIKIVKNNIL RRALKTSNFE GVDESVIKGK IAVAVGINEI LETLKVVDSV VKEKELMKFV CGHFDNRIFN SDDLQKIAKL PGRNELYGMF LSVLQAPLRK FLYALQAVRN AK //