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Protein

Cysteine-rich protein 2

Gene

Crip2

Organism
Rattus norvegicus (Rat)
Status
Reviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

Keywordsi

LigandMetal-binding, Zinc

Names & Taxonomyi

Protein namesi
Recommended name:
Cysteine-rich protein 2
Short name:
CRP-2
Alternative name(s):
Protein ESP1
Gene namesi
Name:Crip2
Synonyms:Crp2
OrganismiRattus norvegicus (Rat)
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeRattus
Proteomesi
  • UP000002494 Componenti: Chromosome 6

Organism-specific databases

RGDi1302959 Crip2

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000757131 – 208Cysteine-rich protein 2Add BLAST208

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei23N6-acetyllysineBy similarity1
Modified residuei104PhosphoserineBy similarity1
Modified residuei138N6-acetyllysineBy similarity1
Modified residuei144N6-acetyllysineBy similarity1

Keywords - PTMi

Acetylation, Phosphoprotein

Proteomic databases

PaxDbiP36201
PRIDEiP36201

PTM databases

iPTMnetiP36201
PhosphoSitePlusiP36201

Expressioni

Tissue specificityi

Expressed more abundantly in liver and kidney of females than that of males. Equally expressed in brain, lung and heart.

Gene expression databases

BgeeiENSRNOG00000005041
GenevisibleiP36201 RN

Interactioni

Subunit structurei

Interacts with TGFB1I1.By similarity

Protein-protein interaction databases

STRINGi10116.ENSRNOP00000006804

Structurei

3D structure databases

ProteinModelPortaliP36201
SMRiP36201
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini5 – 57LIM zinc-binding 1PROSITE-ProRule annotationAdd BLAST53
Domaini126 – 178LIM zinc-binding 2PROSITE-ProRule annotationAdd BLAST53

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Compositional biasi63 – 73Gly-richAdd BLAST11
Compositional biasi180 – 194Gly-richAdd BLAST15

Keywords - Domaini

LIM domain, Repeat

Phylogenomic databases

eggNOGiENOG410ITI5 Eukaryota
ENOG410XUEW LUCA
GeneTreeiENSGT00550000074548
HOGENOMiHOG000111234
HOVERGENiHBG051143
InParanoidiP36201
OMAiSYIYDKP
OrthoDBiEOG091G11RX
PhylomeDBiP36201
TreeFamiTF313758

Family and domain databases

InterProiView protein in InterPro
IPR001781 Znf_LIM
PfamiView protein in Pfam
PF00412 LIM, 2 hits
SMARTiView protein in SMART
SM00132 LIM, 2 hits
PROSITEiView protein in PROSITE
PS00478 LIM_DOMAIN_1, 2 hits
PS50023 LIM_DOMAIN_2, 2 hits

Sequencei

Sequence statusi: Complete.

P36201-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MASKCPKCDK TVYFAEKVSS LGKDWHKFCL KCERCNKTLT PGGHAEHDGK
60 70 80 90 100
PFCHKPCYAT LFGPKGVNIG GAGSYIYEKP PTEAPQVTGP IEVPVVRTEE
110 120 130 140 150
RKTSGPPKGP SKASSVTTFT GEPNMCPRCN KRVYFAEKVT SLGKDWHRPC
160 170 180 190 200
LRCERCSKTL TPGGHAEHDG QPYCHKPCYG ILFGPKGVNT GAVGSYIYDK

DPEGTVQP
Length:208
Mass (Da):22,696
Last modified:June 1, 1994 - v1
Checksum:i6F3B5F8A8FBBAD19
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
D17512 mRNA Translation: BAA04464.1
BC061774 mRNA Translation: AAH61774.1
PIRiS38745
RefSeqiNP_071946.1, NM_022501.1
UniGeneiRn.4267

Genome annotation databases

EnsembliENSRNOT00000006804; ENSRNOP00000006804; ENSRNOG00000005041
GeneIDi338401
KEGGirno:338401
UCSCiRGD:1302959 rat

Similar proteinsi

Entry informationi

Entry nameiCRIP2_RAT
AccessioniPrimary (citable) accession number: P36201
Entry historyiIntegrated into UniProtKB/Swiss-Prot: June 1, 1994
Last sequence update: June 1, 1994
Last modified: May 23, 2018
This is version 117 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome
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Main funding by: National Institutes of Health