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P36183 (ENPL_HORVU) Reviewed, UniProtKB/Swiss-Prot

Last modified March 19, 2014. Version 92. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Endoplasmin homolog
Alternative name(s):
Glucose-regulated protein 94 homolog
Short name=GRP-94 homolog
OrganismHordeum vulgare (Barley)
Taxonomic identifier4513 [NCBI]
Taxonomic lineageEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaLiliopsidaPoalesPoaceaeBEP cladePooideaeTriticeaeHordeum

Protein attributes

Sequence length809 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is further processed into a mature form.
Protein existenceEvidence at transcript level

General annotation (Comments)

Function

May have a molecular chaperone role in the processing of secreted materials By similarity. HAMAP-Rule MF_00505

Subcellular location

Endoplasmic reticulum lumen HAMAP-Rule MF_00505.

Induction

Accumulates rapidly in leaves upon heat shock treatment and during infection by a pathogen. HAMAP-Rule MF_00505

Sequence similarities

Belongs to the heat shock protein 90 family.

Ontologies

Keywords
   Cellular componentEndoplasmic reticulum
   DomainSignal
   LigandATP-binding
Calcium
Nucleotide-binding
   Molecular functionChaperone
   PTMGlycoprotein
Gene Ontology (GO)
   Biological_processprotein folding

Inferred from electronic annotation. Source: InterPro

protein secretion

Inferred from electronic annotation. Source: EnsemblPlants/Gramene

regulation of meristem growth

Inferred from electronic annotation. Source: EnsemblPlants/Gramene

regulation of meristem structural organization

Inferred from electronic annotation. Source: EnsemblPlants/Gramene

response to cadmium ion

Inferred from electronic annotation. Source: EnsemblPlants/Gramene

response to cold

Inferred from electronic annotation. Source: EnsemblPlants/Gramene

response to salt stress

Inferred from electronic annotation. Source: EnsemblPlants/Gramene

response to water deprivation

Inferred from electronic annotation. Source: EnsemblPlants/Gramene

   Cellular_componentapoplast

Inferred from electronic annotation. Source: EnsemblPlants/Gramene

chloroplast

Inferred from electronic annotation. Source: EnsemblPlants/Gramene

endoplasmic reticulum lumen

Inferred from electronic annotation. Source: UniProtKB-SubCell

mitochondrion

Inferred from electronic annotation. Source: EnsemblPlants/Gramene

nucleus

Inferred from electronic annotation. Source: EnsemblPlants/Gramene

plasma membrane

Inferred from electronic annotation. Source: EnsemblPlants/Gramene

plasmodesma

Inferred from electronic annotation. Source: EnsemblPlants/Gramene

vacuolar membrane

Inferred from electronic annotation. Source: EnsemblPlants/Gramene

   Molecular_functionATP binding

Inferred from electronic annotation. Source: UniProtKB-KW

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Signal peptide1 – 1818 Potential
Chain19 – 809791Endoplasmin homolog HAMAP-Rule MF_00505
PRO_0000013603

Regions

Motif806 – 8094Prevents secretion from ER HAMAP-Rule MF_00505

Sites

Binding site1111ATP By similarity
Binding site1551ATP By similarity
Binding site1681ATP By similarity
Binding site1741ATP By similarity
Binding site2001ATP; via amide nitrogen By similarity
Binding site4531ATP By similarity

Amino acid modifications

Glycosylation1111N-linked (GlcNAc...) Potential
Glycosylation4101N-linked (GlcNAc...) Potential
Glycosylation4501N-linked (GlcNAc...) Potential
Glycosylation6171N-linked (GlcNAc...) Potential

Sequences

Sequence LengthMass (Da)Tools
P36183 [UniParc].

Last modified June 1, 1994. Version 1.
Checksum: 79798FDBC15B44D0

FASTA80992,917
        10         20         30         40         50         60 
MRKWALSCAL LLVLLLTTLP DPAKKLQVNA EESSDEVGDF PKVEEKLGAV PHGLSTDSEV 

        70         80         90        100        110        120 
VQRESESISR KTLRNSAEKF EFQAEVSRLM DIIINSLYSN KDIFLRELIS NASDALDKIR 

       130        140        150        160        170        180 
FLALTDKEVM GEGDTAKLEI QIKLDKENKI LSIRDRGVGM TKEDLIKNLG TIAKSGTSAF 

       190        200        210        220        230        240 
VEKMQTGGDL NLIGQFGVGF YSVYLVADYV EVVSKHNDDK QYVWESKADG SFAISEDTWN 

       250        260        270        280        290        300 
EPLGRGTEIK LHLRDEAKEY LEEGKLKDLV KKYSEFINFP IYLWATKEVD VEVPADEEES 

       310        320        330        340        350        360 
NEEEESTTET TEEEETEDDE EKKPKTKTVK ETTTEWELLN DMKAVWLRSP KEVTEEEYAK 

       370        380        390        400        410        420 
FYHSLAKDFG DDKPMSWSHF SAEGDVEFKA LLFVPPKAPH DLYESYYNAN KSNLKLYVRR 

       430        440        450        460        470        480 
VFISDEFDDL LPKYLSFLMG IVDSDTLPLN VSREMLQQHS SLKTIKKKLI RKALDMIRKL 

       490        500        510        520        530        540 
AEEDPDEYSN KEKTDDEKSA MEEKKGQYAK FWNEFGKSVK LGIIEDATNR NRLAKLLRFE 

       550        560        570        580        590        600 
SSKSDGKLVS LDEYISRMKS GQKDIFYLTG SSKEQLEKSP FLEQLTKKNY EVIYFTDPVD 

       610        620        630        640        650        660 
EYLMQYLMDY EDKKFQNVSK EGLKLGKDSK LKDLKESFKE LTDWWKKALD TEGIDSVKIS 

       670        680        690        700        710        720 
NRLHNTPCVV VTSKYGWSSN MEKIMQAQTL SDASKQAYMR GKRVLEINPR HPIIKELRDK 

       730        740        750        760        770        780 
VAQDSDSEGL KQTARLVYQT ALMESGFNLP DPKDFASSIY RSVQKSLDLS PDAAVEEEEE 

       790        800 
VEEPEVEEKE SAKQEAEEPE HEQYDKDEL 

« Hide

References

[1]"A pathogen-induced gene of barley encodes a HSP90 homologue showing striking similarity to vertebrate forms resident in the endoplasmic reticulum."
Walther-Larsen H., Brandt J., Collinge D.B., Thordal-Christensen H.
Plant Mol. Biol. 21:1097-1108(1993) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [MRNA].
Strain: cv. Pallas / P-01.
Tissue: Leaf.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
X67960 mRNA. Translation: CAA48143.1.
PIRS33533.
UniGeneHv.26181.

3D structure databases

ProteinModelPortalP36183.
SMRP36183. Positions 77-287.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

DIPDIP-737N.

Proteomic databases

PRIDEP36183.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Organism-specific databases

GrameneP36183.

Gene expression databases

GenevestigatorP36183.

Family and domain databases

Gene3D3.30.565.10. 1 hit.
HAMAPMF_00505. HSP90.
InterProIPR015566. Endoplasmin.
IPR003594. HATPase_ATP-bd.
IPR019805. Heat_shock_protein_90_CS.
IPR001404. Hsp90_fam.
IPR020575. Hsp90_N.
IPR020568. Ribosomal_S5_D2-typ_fold.
[Graphical view]
PANTHERPTHR11528. PTHR11528. 1 hit.
PTHR11528:SF21. PTHR11528:SF21. 1 hit.
PfamPF00183. HSP90. 1 hit.
[Graphical view]
PIRSFPIRSF002583. Hsp90. 1 hit.
PRINTSPR00775. HEATSHOCK90.
SMARTSM00387. HATPase_c. 1 hit.
[Graphical view]
SUPFAMSSF54211. SSF54211. 1 hit.
SSF55874. SSF55874. 1 hit.
PROSITEPS00014. ER_TARGET. 1 hit.
PS00298. HSP90. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameENPL_HORVU
AccessionPrimary (citable) accession number: P36183
Entry history
Integrated into UniProtKB/Swiss-Prot: June 1, 1994
Last sequence update: June 1, 1994
Last modified: March 19, 2014
This is version 92 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families