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Protein

Endoplasmin homolog

Gene
N/A
Organism
Hordeum vulgare (Barley)
Status
Reviewed-Annotation score: Annotation score: 5 out of 5-Experimental evidence at transcript leveli

Functioni

May have a molecular chaperone role in the processing of secreted materials.By similarity

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei111 – 1111ATPBy similarity
Binding sitei155 – 1551ATPBy similarity
Binding sitei168 – 1681ATPBy similarity
Binding sitei174 – 1741ATPBy similarity
Binding sitei200 – 2001ATP; via amide nitrogenBy similarity
Binding sitei453 – 4531ATPBy similarity

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-KW

GO - Biological processi

  1. gluconeogenesis Source: EnsemblPlants/Gramene
  2. glycolytic process Source: EnsemblPlants/Gramene
  3. Golgi organization Source: EnsemblPlants/Gramene
  4. hyperosmotic response Source: EnsemblPlants/Gramene
  5. N-terminal protein myristoylation Source: EnsemblPlants/Gramene
  6. protein folding Source: EnsemblPlants/Gramene
  7. protein secretion Source: EnsemblPlants/Gramene
  8. regulation of meristem growth Source: EnsemblPlants/Gramene
  9. regulation of meristem structural organization Source: EnsemblPlants/Gramene
  10. response to endoplasmic reticulum stress Source: EnsemblPlants/Gramene
  11. response to heat Source: EnsemblPlants/Gramene
  12. response to high light intensity Source: EnsemblPlants/Gramene
  13. response to hydrogen peroxide Source: EnsemblPlants/Gramene
  14. response to salt stress Source: EnsemblPlants/Gramene
  15. response to water deprivation Source: EnsemblPlants/Gramene
  16. water transport Source: EnsemblPlants/Gramene
Complete GO annotation...

Keywords - Molecular functioni

Chaperone

Keywords - Ligandi

ATP-binding, Calcium, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Endoplasmin homolog
Alternative name(s):
Glucose-regulated protein 94 homolog
Short name:
GRP-94 homolog
OrganismiHordeum vulgare (Barley)
Taxonomic identifieri4513 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaLiliopsidaPoalesPoaceaeBEP cladePooideaeTriticeaeHordeum

Organism-specific databases

GrameneiP36183.

Subcellular locationi

GO - Cellular componenti

  1. apoplast Source: EnsemblPlants/Gramene
  2. chloroplast Source: EnsemblPlants/Gramene
  3. endoplasmic reticulum lumen Source: UniProtKB-SubCell
  4. mitochondrion Source: EnsemblPlants/Gramene
  5. nucleus Source: EnsemblPlants/Gramene
  6. plasma membrane Source: EnsemblPlants/Gramene
  7. plasmodesma Source: EnsemblPlants/Gramene
  8. vacuolar membrane Source: EnsemblPlants/Gramene
Complete GO annotation...

Keywords - Cellular componenti

Endoplasmic reticulum

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Signal peptidei1 – 1818Sequence AnalysisAdd
BLAST
Chaini19 – 809791Endoplasmin homologPRO_0000013603Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Glycosylationi111 – 1111N-linked (GlcNAc...)Sequence Analysis
Glycosylationi410 – 4101N-linked (GlcNAc...)Sequence Analysis
Glycosylationi450 – 4501N-linked (GlcNAc...)Sequence Analysis
Glycosylationi617 – 6171N-linked (GlcNAc...)Sequence Analysis

Keywords - PTMi

Glycoprotein

Proteomic databases

PRIDEiP36183.

Expressioni

Inductioni

Accumulates rapidly in leaves upon heat shock treatment and during infection by a pathogen.

Gene expression databases

ExpressionAtlasiP36183. baseline.
GenevestigatoriP36183.

Interactioni

Protein-protein interaction databases

DIPiDIP-737N.

Structurei

3D structure databases

ProteinModelPortaliP36183.
SMRiP36183. Positions 77-287.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Motif

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Motifi806 – 8094Prevents secretion from ER

Sequence similaritiesi

Belongs to the heat shock protein 90 family.Curated

Keywords - Domaini

Signal

Family and domain databases

Gene3Di3.30.565.10. 1 hit.
HAMAPiMF_00505. HSP90.
InterProiIPR003594. HATPase_C.
IPR019805. Heat_shock_protein_90_CS.
IPR001404. Hsp90_fam.
IPR020575. Hsp90_N.
IPR020568. Ribosomal_S5_D2-typ_fold.
[Graphical view]
PANTHERiPTHR11528. PTHR11528. 1 hit.
PfamiPF00183. HSP90. 1 hit.
[Graphical view]
PIRSFiPIRSF002583. Hsp90. 1 hit.
PRINTSiPR00775. HEATSHOCK90.
SMARTiSM00387. HATPase_c. 1 hit.
[Graphical view]
SUPFAMiSSF54211. SSF54211. 1 hit.
SSF55874. SSF55874. 1 hit.
PROSITEiPS00014. ER_TARGET. 1 hit.
PS00298. HSP90. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

P36183-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MRKWALSCAL LLVLLLTTLP DPAKKLQVNA EESSDEVGDF PKVEEKLGAV
60 70 80 90 100
PHGLSTDSEV VQRESESISR KTLRNSAEKF EFQAEVSRLM DIIINSLYSN
110 120 130 140 150
KDIFLRELIS NASDALDKIR FLALTDKEVM GEGDTAKLEI QIKLDKENKI
160 170 180 190 200
LSIRDRGVGM TKEDLIKNLG TIAKSGTSAF VEKMQTGGDL NLIGQFGVGF
210 220 230 240 250
YSVYLVADYV EVVSKHNDDK QYVWESKADG SFAISEDTWN EPLGRGTEIK
260 270 280 290 300
LHLRDEAKEY LEEGKLKDLV KKYSEFINFP IYLWATKEVD VEVPADEEES
310 320 330 340 350
NEEEESTTET TEEEETEDDE EKKPKTKTVK ETTTEWELLN DMKAVWLRSP
360 370 380 390 400
KEVTEEEYAK FYHSLAKDFG DDKPMSWSHF SAEGDVEFKA LLFVPPKAPH
410 420 430 440 450
DLYESYYNAN KSNLKLYVRR VFISDEFDDL LPKYLSFLMG IVDSDTLPLN
460 470 480 490 500
VSREMLQQHS SLKTIKKKLI RKALDMIRKL AEEDPDEYSN KEKTDDEKSA
510 520 530 540 550
MEEKKGQYAK FWNEFGKSVK LGIIEDATNR NRLAKLLRFE SSKSDGKLVS
560 570 580 590 600
LDEYISRMKS GQKDIFYLTG SSKEQLEKSP FLEQLTKKNY EVIYFTDPVD
610 620 630 640 650
EYLMQYLMDY EDKKFQNVSK EGLKLGKDSK LKDLKESFKE LTDWWKKALD
660 670 680 690 700
TEGIDSVKIS NRLHNTPCVV VTSKYGWSSN MEKIMQAQTL SDASKQAYMR
710 720 730 740 750
GKRVLEINPR HPIIKELRDK VAQDSDSEGL KQTARLVYQT ALMESGFNLP
760 770 780 790 800
DPKDFASSIY RSVQKSLDLS PDAAVEEEEE VEEPEVEEKE SAKQEAEEPE

HEQYDKDEL
Length:809
Mass (Da):92,917
Last modified:June 1, 1994 - v1
Checksum:i79798FDBC15B44D0
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X67960 mRNA. Translation: CAA48143.1.
PIRiS33533.
UniGeneiHv.26181.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X67960 mRNA. Translation: CAA48143.1.
PIRiS33533.
UniGeneiHv.26181.

3D structure databases

ProteinModelPortaliP36183.
SMRiP36183. Positions 77-287.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

DIPiDIP-737N.

Proteomic databases

PRIDEiP36183.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Organism-specific databases

GrameneiP36183.

Gene expression databases

ExpressionAtlasiP36183. baseline.
GenevestigatoriP36183.

Family and domain databases

Gene3Di3.30.565.10. 1 hit.
HAMAPiMF_00505. HSP90.
InterProiIPR003594. HATPase_C.
IPR019805. Heat_shock_protein_90_CS.
IPR001404. Hsp90_fam.
IPR020575. Hsp90_N.
IPR020568. Ribosomal_S5_D2-typ_fold.
[Graphical view]
PANTHERiPTHR11528. PTHR11528. 1 hit.
PfamiPF00183. HSP90. 1 hit.
[Graphical view]
PIRSFiPIRSF002583. Hsp90. 1 hit.
PRINTSiPR00775. HEATSHOCK90.
SMARTiSM00387. HATPase_c. 1 hit.
[Graphical view]
SUPFAMiSSF54211. SSF54211. 1 hit.
SSF55874. SSF55874. 1 hit.
PROSITEiPS00014. ER_TARGET. 1 hit.
PS00298. HSP90. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "A pathogen-induced gene of barley encodes a HSP90 homologue showing striking similarity to vertebrate forms resident in the endoplasmic reticulum."
    Walther-Larsen H., Brandt J., Collinge D.B., Thordal-Christensen H.
    Plant Mol. Biol. 21:1097-1108(1993) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [MRNA].
    Strain: cv. Pallas / P-01.
    Tissue: Leaf.

Entry informationi

Entry nameiENPL_HORVU
AccessioniPrimary (citable) accession number: P36183
Entry historyi
Integrated into UniProtKB/Swiss-Prot: June 1, 1994
Last sequence update: June 1, 1994
Last modified: January 7, 2015
This is version 97 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.