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Protein

DNA replication and repair protein RecF

Gene

recF

Organism
Streptomyces coelicolor (strain ATCC BAA-471 / A3(2) / M145)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity).By similarity

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi30 – 37ATPSequence analysis8

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Biological processi

DNA damage, DNA repair, DNA replication, SOS response

Keywords - Ligandi

ATP-binding, DNA-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
DNA replication and repair protein RecF
Gene namesi
Name:recF
Ordered Locus Names:SCO3876
ORF Names:SCH18.13c
OrganismiStreptomyces coelicolor (strain ATCC BAA-471 / A3(2) / M145)
Taxonomic identifieri100226 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaStreptomycetalesStreptomycetaceaeStreptomycesStreptomyces albidoflavus group
Proteomesi
  • UP000001973 Componenti: Chromosome

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001964701 – 373DNA replication and repair protein RecFAdd BLAST373

Interactioni

Protein-protein interaction databases

STRINGi100226.SCO3876.

Structurei

3D structure databases

ProteinModelPortaliP36176.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the RecF family.Curated

Phylogenomic databases

eggNOGiENOG4105C3X. Bacteria.
COG1195. LUCA.
HOGENOMiHOG000269561.
InParanoidiP36176.
KOiK03629.
OMAiKVQTFIT.
OrthoDBiPOG091H00U7.
PhylomeDBiP36176.

Family and domain databases

Gene3Di3.40.50.300. 2 hits.
HAMAPiMF_00365. RecF. 1 hit.
InterProiIPR001238. DNA-binding_RecF.
IPR018078. DNA-binding_RecF_CS.
IPR027417. P-loop_NTPase.
IPR003395. RecF/RecN/SMC_N.
[Graphical view]
PANTHERiPTHR32182:SF0. PTHR32182:SF0. 1 hit.
PfamiPF02463. SMC_N. 1 hit.
[Graphical view]
SUPFAMiSSF52540. SSF52540. 1 hit.
TIGRFAMsiTIGR00611. recf. 1 hit.
PROSITEiPS00617. RECF_1. 1 hit.
PS00618. RECF_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P36176-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MHVTHLSLAD FRSYARVEVP LDPGVTAFVG PNGQGKTNLV EAVGYLATLG
60 70 80 90 100
SHRVSSDAPL VRMGAERAVI RAQVRQGERQ QLIELELNPG RANRARVNRS
110 120 130 140 150
SQVKPRDVLG IVRTVLFAPE DLALVKGDPG ERRRFLDELI TARSPRMAGV
160 170 180 190 200
RSDYDRVLKQ RNTLLKSAAL ARRHGGRTMD LSTLDVWDQH LARAGAELLA
210 220 230 240 250
QRLDLIASVQ PLADKAYEQL APGGGPVALE YKPSAPGEAH TREDLYEQLM
260 270 280 290 300
AALAEARKQE IERGVTLVGP HRDDLLLKLG SLPAKGYASH GESWSYALAL
310 320 330 340 350
RLASFDLLRA EGNEPVLVLD DVFAELDARR RERLAELVAP GEQVLVTAAV
360 370
DDDVPHVLAG ARFTVAEGTV ERV
Length:373
Mass (Da):40,743
Last modified:June 1, 1994 - v1
Checksum:iC49CF45717F95C84
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
L27063 Genomic DNA. Translation: AAA65213.1.
AL939118 Genomic DNA. Translation: CAB92996.1.
PIRiT10967.
RefSeqiNP_628063.1. NC_003888.3.
WP_003975056.1. NC_003888.3.

Genome annotation databases

EnsemblBacteriaiCAB92996; CAB92996; CAB92996.
GeneIDi1099312.
KEGGisco:SCO3876.
PATRICi23737536. VBIStrCoe124346_3949.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
L27063 Genomic DNA. Translation: AAA65213.1.
AL939118 Genomic DNA. Translation: CAB92996.1.
PIRiT10967.
RefSeqiNP_628063.1. NC_003888.3.
WP_003975056.1. NC_003888.3.

3D structure databases

ProteinModelPortaliP36176.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi100226.SCO3876.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiCAB92996; CAB92996; CAB92996.
GeneIDi1099312.
KEGGisco:SCO3876.
PATRICi23737536. VBIStrCoe124346_3949.

Phylogenomic databases

eggNOGiENOG4105C3X. Bacteria.
COG1195. LUCA.
HOGENOMiHOG000269561.
InParanoidiP36176.
KOiK03629.
OMAiKVQTFIT.
OrthoDBiPOG091H00U7.
PhylomeDBiP36176.

Family and domain databases

Gene3Di3.40.50.300. 2 hits.
HAMAPiMF_00365. RecF. 1 hit.
InterProiIPR001238. DNA-binding_RecF.
IPR018078. DNA-binding_RecF_CS.
IPR027417. P-loop_NTPase.
IPR003395. RecF/RecN/SMC_N.
[Graphical view]
PANTHERiPTHR32182:SF0. PTHR32182:SF0. 1 hit.
PfamiPF02463. SMC_N. 1 hit.
[Graphical view]
SUPFAMiSSF52540. SSF52540. 1 hit.
TIGRFAMsiTIGR00611. recf. 1 hit.
PROSITEiPS00617. RECF_1. 1 hit.
PS00618. RECF_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiRECF_STRCO
AccessioniPrimary (citable) accession number: P36176
Entry historyi
Integrated into UniProtKB/Swiss-Prot: June 1, 1994
Last sequence update: June 1, 1994
Last modified: September 7, 2016
This is version 104 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.